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CA2382852A1 - Polypeptides - Google Patents

Polypeptides Download PDF

Info

Publication number
CA2382852A1
CA2382852A1 CA002382852A CA2382852A CA2382852A1 CA 2382852 A1 CA2382852 A1 CA 2382852A1 CA 002382852 A CA002382852 A CA 002382852A CA 2382852 A CA2382852 A CA 2382852A CA 2382852 A1 CA2382852 A1 CA 2382852A1
Authority
CA
Canada
Prior art keywords
polypeptide
smad
tgf
mixer
interacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002382852A
Other languages
English (en)
Inventor
Stephane Edouard Germain
Caroline Susan Hill
Michael Terence Howell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Technology Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2382852A1 publication Critical patent/CA2382852A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne un polypeptide (polypeptide d'interaction) capable de réagir mutuellement avec un polypeptide Smad, le polypeptide d'interaction comprenant la séquence d'acide aminé PP(T/N)K et comporte moins de 150 acides aminés en longueur ou ne représente pas un Xenopus pleine longueur ou un FAST1 humain ou un fragment de celui-ci, un FAST2 de souris, un Xenopus Milk, un Xenopus Mixer ou un Xenopus Bix2. Le polypeptide Smad peut être un Smad2 ou un Smad3. Les polypeptides d'interaction sont utiles en médecine dans les tests de criblage.
CA002382852A 1999-08-25 2000-08-25 Polypeptides Abandoned CA2382852A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9920000.8 1999-08-25
GBGB9920000.8A GB9920000D0 (en) 1999-08-25 1999-08-25 Polypeptides
PCT/GB2000/003265 WO2001014413A2 (fr) 1999-08-25 2000-08-25 Polypeptides

Publications (1)

Publication Number Publication Date
CA2382852A1 true CA2382852A1 (fr) 2001-03-01

Family

ID=10859702

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002382852A Abandoned CA2382852A1 (fr) 1999-08-25 2000-08-25 Polypeptides

Country Status (5)

Country Link
EP (1) EP1212414A2 (fr)
AU (1) AU6712600A (fr)
CA (1) CA2382852A1 (fr)
GB (1) GB9920000D0 (fr)
WO (1) WO2001014413A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0105063D0 (en) * 2001-03-01 2001-04-18 Imp Cancer Res Tech Polypeptides
CN103558395B (zh) * 2013-10-28 2015-08-26 深圳市第二人民医院 Smad3基因在检测上尿路上皮癌中的应用
CN115960167B (zh) * 2022-08-18 2023-11-07 齐齐哈尔大学 一种玉米抗粘附肽及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184205B1 (en) * 1994-07-22 2001-02-06 University Of North Carolina At Chapel Hill GRB2 SH3 binding peptides and methods of isolating and using same
FR2726471B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins
FR2766192B1 (fr) * 1997-07-17 2001-07-13 Pf Medicament Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
AU774694B2 (en) * 1998-12-16 2004-07-01 Temple University - Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by high molecular weight kininogen domain 3 peptide analogs
AU2736600A (en) * 1999-01-26 2000-08-07 Scripps Research Institute, The Control of virus infection using replication associated proteins, compositions and methods of use
GB9909133D0 (en) * 1999-04-22 1999-06-16 Peptide Therapeutics Ltd Inhibition of endopeptidase by cystatins

Also Published As

Publication number Publication date
WO2001014413A3 (fr) 2001-09-07
WO2001014413A2 (fr) 2001-03-01
EP1212414A2 (fr) 2002-06-12
GB9920000D0 (en) 1999-10-27
AU6712600A (en) 2001-03-19

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Legal Events

Date Code Title Description
FZDE Discontinued