CA2378257A1 - Procede permettant d'augmenter l'ecoulement sanguin dans le nerf optique, la retine et la choroide afin de faciliter la preservation de la vue - Google Patents
Procede permettant d'augmenter l'ecoulement sanguin dans le nerf optique, la retine et la choroide afin de faciliter la preservation de la vue Download PDFInfo
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- CA2378257A1 CA2378257A1 CA002378257A CA2378257A CA2378257A1 CA 2378257 A1 CA2378257 A1 CA 2378257A1 CA 002378257 A CA002378257 A CA 002378257A CA 2378257 A CA2378257 A CA 2378257A CA 2378257 A1 CA2378257 A1 CA 2378257A1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention concerne un procédé permettant d'améliorer la fonction visuelle et d'augmenter le plus possible la santé du nerf optique et de la rétine par augmentation de la vitesse de l'écoulement sanguin. Ce procédé consiste à appliquer une quantité efficace d'une préparation d'un agent augmentant les niveaux de GMP cyclique et les niveaux d'oxyde nitrique ou inhibant la phosphodiestérase.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14815099P | 1999-08-10 | 1999-08-10 | |
| US60/148,150 | 1999-08-10 | ||
| PCT/US2000/021929 WO2001010406A2 (fr) | 1999-08-10 | 2000-08-10 | Procede permettant d'augmenter l'ecoulement sanguin dans le nerf optique, la retine et la choroide afin de faciliter la preservation de la vue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2378257A1 true CA2378257A1 (fr) | 2001-02-15 |
Family
ID=22524518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002378257A Abandoned CA2378257A1 (fr) | 1999-08-10 | 2000-08-10 | Procede permettant d'augmenter l'ecoulement sanguin dans le nerf optique, la retine et la choroide afin de faciliter la preservation de la vue |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1246605A2 (fr) |
| JP (1) | JP2003506394A (fr) |
| AU (1) | AU779991B2 (fr) |
| CA (1) | CA2378257A1 (fr) |
| WO (1) | WO2001010406A2 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI265925B (en) | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
| EP1093814A1 (fr) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Utilisation du dipyridamole ou du mopidamol dans la fabrication d'un médicament pour le traitement et la prévention des troubles de la microcirculation dépendants de la fibrine |
| SE0202365D0 (sv) | 2002-08-05 | 2002-08-05 | Pharmacia Ab | New formulation and use thereof |
| AU2004257693B8 (en) | 2003-07-09 | 2009-08-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of nitrite salts for the treatment of cardiovascular conditions |
| EP2052720A3 (fr) * | 2003-11-20 | 2009-05-06 | Othera Holding, Inc. | Utilisation d'au moins un composé d'hydroxylamine pour le traitement de maladies oculaires |
| WO2006058318A2 (fr) * | 2004-11-29 | 2006-06-01 | The University Of Akron | Dispositifs donneurs de monoxyde d'azote topiques et leurs methodes d'utilisation a des fins therapeutiques |
| US8088773B2 (en) * | 2005-05-12 | 2012-01-03 | The Texas A&M University System | Therapeutic compositions and methods |
| US8557300B2 (en) | 2005-05-19 | 2013-10-15 | University Of Cincinnati | Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite |
| JP5162859B2 (ja) * | 2005-08-31 | 2013-03-13 | 大正製薬株式会社 | 眼精疲労の予防又は緩和剤 |
| US20120237617A1 (en) * | 2009-06-18 | 2012-09-20 | Theravasc Inc. | Use of nitrite salts in treating tissue damage |
| JP5791064B2 (ja) * | 2009-07-17 | 2015-10-07 | エア・ウォーター株式会社 | 医薬用組成物 |
| KR20150032552A (ko) | 2012-06-11 | 2015-03-26 | 매큐클리어 인코포레이션 | 치료 제제 및 치료 방법 |
| FR3008618A1 (fr) * | 2013-07-19 | 2015-01-23 | Univ Paris Curie | Utilisation de composes pour restaurer la reponse a la lumiere des cellules de la retine |
| CN115282152A (zh) * | 2015-01-28 | 2022-11-04 | 瑞采生技有限公司 | 用于增强PPARγ表现及核转位之化合物及其医疗用途 |
| SG11201811160XA (en) * | 2016-06-21 | 2019-01-30 | Univ Newcastle | Treatment for myopia |
| EP3949958A1 (fr) * | 2020-08-04 | 2022-02-09 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Composé pour le traitement et la prévention d'une maladie associée à la lipofuscine |
| EP4154888A1 (fr) * | 2021-09-24 | 2023-03-29 | Charité - Universitätsmedizin Berlin | Inhibiteur pde5 destiné à être utilisés dans le traitement d'affections médicales associées à un déficit en complexe v mitochondrial |
| CN114177182A (zh) * | 2021-12-25 | 2022-03-15 | 三维医疗科技有限公司 | 枸橼酸西地那非/他达拉非/伐地那非在制备治疗近视药物中的应用 |
| EP4233867B1 (fr) * | 2022-02-24 | 2025-09-03 | Nicox SA | Inhibiteur de pde5 pour utilisation dans le traitement de la neuropathie optique ischémique antérieure |
| CN118976010A (zh) * | 2022-12-05 | 2024-11-19 | 齐鲁制药有限公司 | 一种司美格鲁肽吸入喷雾剂及其制备方法 |
| WO2024200678A1 (fr) | 2023-03-28 | 2024-10-03 | Charité - Universitätsmedizin Berlin | Inhibiteur de pde5 destiné à être utilisé dans le traitement d'états médicaux associés à un déficit en complexe iv mitochondrial |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0733745A (ja) * | 1993-07-19 | 1995-02-03 | Taiho Yakuhin Kogyo Kk | ２−ニトロイミダゾール化合物 |
| US5780450A (en) * | 1995-11-21 | 1998-07-14 | Alcon Laboratories, Inc. | Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage |
| SI0975347T1 (sl) * | 1997-02-28 | 2008-08-31 | Nycomed Gmbh | Sinergistična kombinacija PDE inhibitorjev in agonistov adenilat ciklaze oziroma agonistov gvanil ciklize |
-
2000
- 2000-08-10 JP JP2001514927A patent/JP2003506394A/ja not_active Withdrawn
- 2000-08-10 EP EP00952721A patent/EP1246605A2/fr not_active Withdrawn
- 2000-08-10 WO PCT/US2000/021929 patent/WO2001010406A2/fr not_active Ceased
- 2000-08-10 AU AU65365/00A patent/AU779991B2/en not_active Ceased
- 2000-08-10 CA CA002378257A patent/CA2378257A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003506394A (ja) | 2003-02-18 |
| AU6536500A (en) | 2001-03-05 |
| AU779991B2 (en) | 2005-02-24 |
| WO2001010406A2 (fr) | 2001-02-15 |
| WO2001010406A3 (fr) | 2002-08-08 |
| EP1246605A2 (fr) | 2002-10-09 |
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