CA2364730A1 - Lipides comportant un groupe aminoxy - Google Patents

Lipides comportant un groupe aminoxy Download PDF

Info

Publication number: CA2364730A1
Authority: CA; Canada
Prior art keywords: group; compound; lipid; invention according; nmr
Prior art date: 2000-12-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002364730A

Other languages

English (en)

Inventor

Michael Jorgensen

Michael Keller

Andrew David Miller

Eric Perouzel

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Mitsubishi Chemical Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-12

Filing date

2001-12-06

Publication date

2002-06-12

2000-12-12 Priority claimed from PCT/GB2000/004767 external-priority patent/WO2001048233A1/fr

2001-06-06 Priority claimed from GB0113781A external-priority patent/GB2372502B/en

2001-12-05 Priority claimed from CA002364392A external-priority patent/CA2364392A1/fr

2001-12-06 Application filed by Individual filed Critical Individual

2001-12-06 Priority to CA002364730A priority Critical patent/CA2364730A1/fr

2002-06-12 Publication of CA2364730A1 publication Critical patent/CA2364730A1/fr

Status Abandoned legal-status Critical Current

Links

150000002632 lipids Chemical class 0.000 title claims description 37
125000002344 aminooxy group Chemical group [H]N([H])O[*] 0.000 title description 4
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125000003473 lipid group Chemical group 0.000 claims abstract 4
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238000000034 method Methods 0.000 claims description 26
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 24
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125000001424 substituent group Chemical group 0.000 claims description 11
239000002253 acid Substances 0.000 claims description 10
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RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 8
235000012000 cholesterol Nutrition 0.000 claims description 7
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ATHGHQPFGPMSJY-UHFFFAOYSA-N spermidine Chemical compound NCCCCNCCCN ATHGHQPFGPMSJY-UHFFFAOYSA-N 0.000 claims description 6
PFNFFQXMRSDOHW-UHFFFAOYSA-N spermine Chemical compound NCCCNCCCCNCCCN PFNFFQXMRSDOHW-UHFFFAOYSA-N 0.000 claims description 6
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DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 1
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MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
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Landscapes

Steroid Compounds (AREA)

CA002364730A 2000-12-12 2001-12-06 Lipides comportant un groupe aminoxy Abandoned CA2364730A1 (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA002364730A CA2364730A1 (fr)	2000-12-12	2001-12-06	Lipides comportant un groupe aminoxy

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
PCT/GB2000/004767 WO2001048233A1 (fr)	1999-12-23	2000-12-12	Complexes d'administration a base d'acides nucleiques-lipide cationique-proteine noyau virale
WOPCT/GB00/04767		2000-12-12
GB0113781.9		2001-06-06
GB0113781A GB2372502B (en)	2000-12-12	2001-06-06	Carbohydrate compounds containing cholesterol and their use
CA2,364,392		2001-12-05
CA002364392A CA2364392A1 (fr)	2000-12-12	2001-12-05	Compose
CA002364730A CA2364730A1 (fr)	2000-12-12	2001-12-06	Lipides comportant un groupe aminoxy

Publications (1)

Publication Number	Publication Date
CA2364730A1 true CA2364730A1 (fr)	2002-06-12

Family

ID=27427723

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002364730A Abandoned CA2364730A1 (fr)	2000-12-12	2001-12-06	Lipides comportant un groupe aminoxy

Country Status (1)

Country	Link
CA (1)	CA2364730A1 (fr)

2001
- 2001-12-06 CA CA002364730A patent/CA2364730A1/fr not_active Abandoned

Publication	Publication Date	Title
JP4074658B2 (ja)	2008-04-09	自己構築ポリヌクレオチド送達システム
US6989434B1 (en)	2006-01-24	Reagents for intracellular delivery of macromolecules
US6075012A (en)	2000-06-13	Reagents for intracellular delivery of macromolecules
DE69324367T2 (de)	1999-09-23	Kationische lipide
DE60026164T2 (de)	2006-11-16	Virale kernproteine-kationische lipid-nukleinsäure-verabreichungkomplexe
JPH11511757A (ja)	1999-10-12	治療用分子を細胞内投与するためのカチオン両親媒性物質と補助脂質とを含む組成物
Perouzel et al.	2003	Synthesis and formulation of neoglycolipids for the functionalization of liposomes and lipoplexes
EP1351972B1 (fr)	2006-03-01	Lipides comprenant un groupe aminoxy
AU2002222128A1 (en)	2002-08-29	Lipids comprising an aminoxy group
US20020188023A1 (en)	2002-12-12	Compound
US20050064023A1 (en)	2005-03-24	Compound
JPH09512270A (ja)	1997-12-09	細胞形質転換のための組成物および方法
CA2364730A1 (fr)	2002-06-12	Lipides comportant un groupe aminoxy
EP1669366A1 (fr)	2006-06-14	Lipides comprenant un group aminoxy
HK1057048B (en)	2006-07-14	Lipids comprising an aminoxy group
US20050287202A1 (en)	2005-12-29	Compound
GB2372502A (en)	2002-08-28	Cholesterol-carbohydrate compound for treating genetic disorders
WO1998050416A1 (fr)	1998-11-12	Amphiphiles cationiques a groupes lipophiles steroides multiples
WO2025051994A1 (fr)	2025-03-13	Nanoparticules lipidiques ionisables

Legal Events

Date	Code	Title	Description
2003-12-31	EEER	Examination request
2011-12-06	FZDE	Discontinued