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CA2364002A1 - Peptides immunogenes derives de mage-3 presentes par le complexe majeur d'histocompatibilte (mch) de categorie ii et utilisations associees - Google Patents

Peptides immunogenes derives de mage-3 presentes par le complexe majeur d'histocompatibilte (mch) de categorie ii et utilisations associees Download PDF

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Publication number
CA2364002A1
CA2364002A1 CA002364002A CA2364002A CA2364002A1 CA 2364002 A1 CA2364002 A1 CA 2364002A1 CA 002364002 A CA002364002 A CA 002364002A CA 2364002 A CA2364002 A CA 2364002A CA 2364002 A1 CA2364002 A1 CA 2364002A1
Authority
CA
Canada
Prior art keywords
cells
peptides
mage
hla
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002364002A
Other languages
English (en)
Inventor
Maria Pia Protti
Paolo Dellabona
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ospedale San Raffaele SRL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2364002A1 publication Critical patent/CA2364002A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des peptides dérivés de la protéine MAGE-3, des compositions pharmaceutiques qui contiennent ces peptides et leurs utilisations dans l'induction de réponse immune contre des tumeurs.
CA002364002A 1999-02-26 2000-02-23 Peptides immunogenes derives de mage-3 presentes par le complexe majeur d'histocompatibilte (mch) de categorie ii et utilisations associees Abandoned CA2364002A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI000396A IT1309584B1 (it) 1999-02-26 1999-02-26 Peptidi immunogenici derivati da mage-3 presentati da mhc di classeii e loro uso.
ITMI99A000396 1999-02-26
PCT/EP2000/001458 WO2000052045A2 (fr) 1999-02-26 2000-02-23 Peptides immunogenes derives de mage-3 presentes par le complexe majeur d'histocompatibilte (mch) de categorie ii et utilisations associees

Publications (1)

Publication Number Publication Date
CA2364002A1 true CA2364002A1 (fr) 2000-09-08

Family

ID=11382063

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002364002A Abandoned CA2364002A1 (fr) 1999-02-26 2000-02-23 Peptides immunogenes derives de mage-3 presentes par le complexe majeur d'histocompatibilte (mch) de categorie ii et utilisations associees

Country Status (6)

Country Link
EP (1) EP1161443A2 (fr)
JP (1) JP2002538166A (fr)
AU (1) AU2913400A (fr)
CA (1) CA2364002A1 (fr)
IT (1) IT1309584B1 (fr)
WO (1) WO2000052045A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001253029A1 (en) * 2000-03-30 2001-10-15 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services T-cell epitope of mage-12 and related nucleic acids, vectors, cells, compositions and methods of inducing an immune response to cancer
US7049413B2 (en) 2001-05-18 2006-05-23 Ludwig Institute For Cancer Research MAGE-A3 peptides presented by HLA class II molecules
US7842480B2 (en) 2001-05-18 2010-11-30 Mayo Foundation For Medical Education And Research Chimeric antigen-specific t cell-activating polypeptides
US20060222656A1 (en) 2005-04-01 2006-10-05 University Of Maryland, Baltimore MAGE-A3/HPV 16 peptide vaccines for head and neck cancer
FR2837837B1 (fr) 2002-03-28 2006-09-29 Roussy Inst Gustave Epitopes peptidiques communs a des antigenes d'une meme famille multigenique
EP1715343B1 (fr) * 2005-04-20 2009-12-09 F. Hoffmann-La Roche Ag Méthode d'identification des épitopes en rapport avec l'immunogénicité des produits bio-pharmaceutiques
WO2008053573A1 (fr) * 2006-10-30 2008-05-08 National University Corporation Hokkaido University Remède pour néoplasme malin
WO2015184224A1 (fr) * 2014-05-30 2015-12-03 Academia Sinica Aptamère ciblant le peptide mage-a3 et utilisations associées
GB201804468D0 (en) 2018-03-21 2018-05-02 Valo Therapeutics Oy PeptiCRAd Cancer Therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5662907A (en) * 1992-08-07 1997-09-02 Cytel Corporation Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes
WO1994020127A1 (fr) * 1993-03-05 1994-09-15 Cytel Corporation Peptides se liant a hla-a2.1 et leurs utilisations
CA2278189A1 (fr) * 1997-01-31 1998-08-06 Epimmune, Inc. Cellules a peptides ou a antigenes charges de peptides
WO1999003972A1 (fr) * 1997-07-15 1999-01-28 Takara Shuzo Co., Ltd. Lymphocytes t cytotoxiques
US5965535A (en) * 1997-09-12 1999-10-12 Ludwig Institute For Cancer Research Mage-3 peptides presented by HLA class II molecules
JP2002507397A (ja) * 1998-03-13 2002-03-12 エピミューン,インコーポレイティド Hla結合ペプチド及びその使用

Also Published As

Publication number Publication date
JP2002538166A (ja) 2002-11-12
EP1161443A2 (fr) 2001-12-12
IT1309584B1 (it) 2002-01-24
ITMI990396A1 (it) 2000-08-26
AU2913400A (en) 2000-09-21
WO2000052045A3 (fr) 2001-01-04
WO2000052045A2 (fr) 2000-09-08

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued