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CA2361575A1 - Formulations a base de l-arginine utilisees dans le traitement de maladies, et leurs procedes d'utilisation - Google Patents

Formulations a base de l-arginine utilisees dans le traitement de maladies, et leurs procedes d'utilisation Download PDF

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Publication number
CA2361575A1
CA2361575A1 CA002361575A CA2361575A CA2361575A1 CA 2361575 A1 CA2361575 A1 CA 2361575A1 CA 002361575 A CA002361575 A CA 002361575A CA 2361575 A CA2361575 A CA 2361575A CA 2361575 A1 CA2361575 A1 CA 2361575A1
Authority
CA
Canada
Prior art keywords
arginine
nos
agonist
nitric oxide
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002361575A
Other languages
English (en)
Inventor
Wayne H. Kaesemeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiogenix Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2361575A1 publication Critical patent/CA2361575A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne un mélange thérapeutique à base de L-arginine et d'agoniste d'oxyde nitrique synthase (NOS), (par exemple, la Doxazosine), utilisé dans le traitement de maladies.
CA002361575A 1999-02-05 2000-02-04 Formulations a base de l-arginine utilisees dans le traitement de maladies, et leurs procedes d'utilisation Abandoned CA2361575A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11890399P 1999-02-05 1999-02-05
US60/118,903 1999-02-05
PCT/US2000/002798 WO2000045809A1 (fr) 1999-02-05 2000-02-04 Formulations a base de l-arginine utilisees dans le traitement de maladies, et leurs procedes d'utilisation

Publications (1)

Publication Number Publication Date
CA2361575A1 true CA2361575A1 (fr) 2000-08-10

Family

ID=22381443

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002361575A Abandoned CA2361575A1 (fr) 1999-02-05 2000-02-04 Formulations a base de l-arginine utilisees dans le traitement de maladies, et leurs procedes d'utilisation

Country Status (6)

Country Link
EP (1) EP1150669A4 (fr)
JP (1) JP2002536325A (fr)
AU (1) AU3356000A (fr)
CA (1) CA2361575A1 (fr)
MX (1) MXPA01007952A (fr)
WO (1) WO2000045809A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6425881B1 (en) * 1994-10-05 2002-07-30 Nitrosystems, Inc. Therapeutic mixture useful in inhibiting lesion formation after vascular injury
US5968983A (en) 1994-10-05 1999-10-19 Nitrosystems, Inc Method and formulation for treating vascular disease
JP2002539257A (ja) 1999-03-19 2002-11-19 イーノス・ファーマシューティカルス・インコーポレーテッド 薬剤の脳内生物学的利用率の増加
JP5065570B2 (ja) * 2002-09-06 2012-11-07 第一三共ヘルスケア株式会社 血管内皮性酸化窒素の合成促進剤
JP2007502135A (ja) * 2003-08-14 2007-02-08 ブルー・メディカル・デバイシーズ・ベスローテン・フェンノートシャップ 治療剤を含んで成る腔内人工器官
EP1591118A1 (fr) * 2004-04-27 2005-11-02 Nutri-Fit GmbH & Co. KG Utilisation de la mélatonine pour prévenir des complications postopératoires
JP2012041296A (ja) * 2010-08-19 2012-03-01 Medience Corp 血管内皮機能改善剤、一酸化窒素産生促進剤、及び飲食品

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758569A (en) * 1987-08-26 1988-07-19 Pfizer Inc. Doxazosin as an anti-atherosclerosis agent
US5270323A (en) * 1990-05-31 1993-12-14 Pfizer Inc. Method of treating impotence
CA2147357A1 (fr) * 1992-11-04 1994-05-11 Nancy M. Gray Methodes et compositions a base de (+)-doxazosine pour le traitement de l'hypertension
WO1994028721A1 (fr) * 1993-06-11 1994-12-22 The Board Of Trustees Of The Leland Stanford Junior University Traitement des maladies vasculaires degeneratives par modulation de l'activite ou de la production d'oxyde nitrique endogene
US5543430A (en) * 1994-10-05 1996-08-06 Kaesemeyer; W. H. Method and formulation of stimulating nitric oxide synthesis
DE69533584T2 (de) * 1995-06-01 2005-02-17 N.V. Nutricia Klinische Nährungszusammensetzung
FR2774593B1 (fr) * 1998-02-12 2000-05-05 Philippe Gorny Obtention d'un medicament destine a combattre les dysfonctions sexuelles feminines
US6277884B1 (en) * 1998-06-01 2001-08-21 Nitromed, Inc. Treatment of sexual dysfunction with N-hydroxyguanidine compounds

Also Published As

Publication number Publication date
EP1150669A4 (fr) 2005-06-22
JP2002536325A (ja) 2002-10-29
MXPA01007952A (es) 2004-03-26
EP1150669A1 (fr) 2001-11-07
WO2000045809A1 (fr) 2000-08-10
AU3356000A (en) 2000-08-25

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Legal Events

Date Code Title Description
FZDE Dead