CA2355134A1 - Procedes et produits pour la caracterisation et l'analyse des sequences d'adn peptidique - Google Patents
Procedes et produits pour la caracterisation et l'analyse des sequences d'adn peptidique Download PDFInfo
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- CA2355134A1 CA2355134A1 CA002355134A CA2355134A CA2355134A1 CA 2355134 A1 CA2355134 A1 CA 2355134A1 CA 002355134 A CA002355134 A CA 002355134A CA 2355134 A CA2355134 A CA 2355134A CA 2355134 A1 CA2355134 A1 CA 2355134A1
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- 108010059378 Endopeptidases Proteins 0.000 description 1
- 102000005593 Endopeptidases Human genes 0.000 description 1
- 241000701533 Escherichia virus T4 Species 0.000 description 1
- 108700024394 Exon Proteins 0.000 description 1
- 101710127406 Glycoprotein 5 Proteins 0.000 description 1
- 108091027305 Heteroduplex Proteins 0.000 description 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 description 1
- 108020004485 Nonsense Codon Proteins 0.000 description 1
- 101710163270 Nuclease Proteins 0.000 description 1
- 102100021010 Nucleolin Human genes 0.000 description 1
- 102000043276 Oncogene Human genes 0.000 description 1
- 238000012408 PCR amplification Methods 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 108010090804 Streptavidin Proteins 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N adenyl group Chemical group N1=CN=C2N=CNC2=C1N GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- MGSKVZWGBWPBTF-UHFFFAOYSA-N aebsf Chemical compound NCCC1=CC=C(S(F)(=O)=O)C=C1 MGSKVZWGBWPBTF-UHFFFAOYSA-N 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
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- XMQFTWRPUQYINF-UHFFFAOYSA-N bensulfuron-methyl Chemical compound COC(=O)C1=CC=CC=C1CS(=O)(=O)NC(=O)NC1=NC(OC)=CC(OC)=N1 XMQFTWRPUQYINF-UHFFFAOYSA-N 0.000 description 1
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- 230000002759 chromosomal effect Effects 0.000 description 1
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- 238000013461 design Methods 0.000 description 1
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- 238000005259 measurement Methods 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 108010091212 pepstatin Proteins 0.000 description 1
- FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical compound OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 description 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
- 239000013600 plasmid vector Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 150000003147 proline derivatives Chemical class 0.000 description 1
- 230000001915 proofreading effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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- 239000012588 trypsin Substances 0.000 description 1
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- 229950009811 ubenimex Drugs 0.000 description 1
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- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention concerne un fragment d'acide nucléique incorporé dans un gène artificiel hybride et exprimé dans un ou plusieurs cadres de lecture de manière à produire un ou plusieurs polypeptides hybrides. Les polypeptides sont examinés sous l'angle d'un ou plusieurs paramètres physiques (par exemple, masse ou composition d'acides aminés). Les valeurs des paramètres examinés sont utilisées pour rechercher un ensemble de paramètres prévus résultant de la traduction hypothétique d'une séquence nucléotidique de référence plus importante, de manière à déterminer si le fragment est contenu dans la séquence de référence et, si tel est le cas, de manière à déterminer la séquence et/ou la capacité de codage de ce fragment.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11235198P | 1998-12-16 | 1998-12-16 | |
| US60/112,351 | 1998-12-16 | ||
| PCT/US1999/030104 WO2000036414A1 (fr) | 1998-12-16 | 1999-12-16 | Procedes et produits pour la caracterisation et l'analyse des sequences d'adn peptidique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2355134A1 true CA2355134A1 (fr) | 2000-06-22 |
Family
ID=22343436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002355134A Abandoned CA2355134A1 (fr) | 1998-12-16 | 1999-12-16 | Procedes et produits pour la caracterisation et l'analyse des sequences d'adn peptidique |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1151296A4 (fr) |
| AU (1) | AU2710700A (fr) |
| CA (1) | CA2355134A1 (fr) |
| WO (1) | WO2000036414A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105588909B (zh) * | 2015-12-15 | 2020-08-25 | 中国肉类食品综合研究中心 | 基于液相色谱串联质谱技术测定多种动物源性肉类的方法 |
| CN113945649B (zh) * | 2021-08-18 | 2023-08-18 | 中国农业科学院农业质量标准与检测技术研究所 | 不同加工工艺的牛奶的蛋白组生物标志物及其筛选方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5620848A (en) * | 1990-06-27 | 1997-04-15 | Trustees Of Princeton University | Methods for detecting mutant p53 |
| US5702890A (en) * | 1993-07-26 | 1997-12-30 | K.O. Technology, Inc. | Inhibitors of alternative alleles of genes as a basis for cancer therapeutic agents |
| US6017693A (en) * | 1994-03-14 | 2000-01-25 | University Of Washington | Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry |
| US5876940A (en) * | 1994-11-30 | 1999-03-02 | University Of Utah Research Foundation | Alleles |
| US6207370B1 (en) * | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
-
1999
- 1999-12-16 AU AU27107/00A patent/AU2710700A/en not_active Abandoned
- 1999-12-16 CA CA002355134A patent/CA2355134A1/fr not_active Abandoned
- 1999-12-16 WO PCT/US1999/030104 patent/WO2000036414A1/fr not_active Ceased
- 1999-12-16 EP EP99968909A patent/EP1151296A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1151296A4 (fr) | 2005-01-26 |
| WO2000036414A1 (fr) | 2000-06-22 |
| EP1151296A1 (fr) | 2001-11-07 |
| AU2710700A (en) | 2000-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |