[go: up one dir, main page]

CA2211681A1 - Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient - Google Patents

Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient

Info

Publication number
CA2211681A1
CA2211681A1 CA002211681A CA2211681A CA2211681A1 CA 2211681 A1 CA2211681 A1 CA 2211681A1 CA 002211681 A CA002211681 A CA 002211681A CA 2211681 A CA2211681 A CA 2211681A CA 2211681 A1 CA2211681 A1 CA 2211681A1
Authority
CA
Canada
Prior art keywords
halogeno
same
represents hydrogen
salts
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002211681A
Other languages
French (fr)
Other versions
CA2211681C (en
Inventor
Akira Yazaki
Jiro Yoshida
Yoshiko Niino
Yoshihiro Ohshita
Norihiro Hayashi
Hirotaka Amano
Yuzo Hirao
Yasuhiro Kuramoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wakunaga Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2211681A1 publication Critical patent/CA2211681A1/en
Application granted granted Critical
Publication of CA2211681C publication Critical patent/CA2211681C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A pyridonecarboxylic acid derivative represented by general formula (1) or a salt thereof and an antibacterial agent containing the same, wherein R1 represents hydrogen or a carboxy protecting group; R2 represents nitro or optionally substituted amino; R3 represents halogeno; R4 and R5 may be the same or different and each represents hydrogen, halogeno, lower alkyl or lower alkoxy; R6 represents hydrogen, halogeno, hydroxy, lower alkyl or amino; R7 represents hydrogen or halogeno; A represents nitrogen or -CX= (wherein X represents hydrogen, halogeno, lower alkyl or lower alkoxy); and Z represents halogeno or optionally substituted, saturated cyclic amino.
CA002211681A 1995-01-30 1996-01-26 Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient Expired - Fee Related CA2211681C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7-12673 1995-01-30
JP1267395 1995-01-30
PCT/JP1996/000152 WO1996023775A1 (en) 1995-01-30 1996-01-26 Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agent containing the same as active ingredient

Publications (2)

Publication Number Publication Date
CA2211681A1 true CA2211681A1 (en) 1996-01-30
CA2211681C CA2211681C (en) 2003-05-13

Family

ID=11811900

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002211681A Expired - Fee Related CA2211681C (en) 1995-01-30 1996-01-26 Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient

Country Status (4)

Country Link
KR (1) KR100499366B1 (en)
AU (1) AU5260096A (en)
CA (1) CA2211681C (en)
WO (1) WO1996023775A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE222906T1 (en) * 1995-09-22 2002-09-15 Wakunaga Pharma Co Ltd PYRIDONE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL ACTIVE INGREDIENTS
KR20000005398A (en) * 1996-04-16 2000-01-25 기스케 와구나가, 구사이 요시히로 NOVEL PHENYLENEthiamineS AND ITS PREPARING METHOD
EP0897919B1 (en) * 1996-04-19 2004-06-16 Wakunaga Pharmaceutical Co., Ltd. Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing the same as the active ingredient
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
MA24500A1 (en) 1997-03-21 1998-10-01 Lg Life Sciences Ltd CARBOXYLIC ACID SALT DERIVATIVE FROM NAPHTHYRIDINE.
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
MX377642B (en) * 2016-06-15 2025-03-11 Wakunaga Pharma Co Ltd Novel pyridonecarboxylic acid derivative or salt thereof
CN116606279A (en) * 2023-03-13 2023-08-18 广东工业大学 A kind of fluoroquinolone compound and its preparation method and application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8524662D0 (en) * 1985-10-07 1985-11-13 Fujisawa Pharmaceutical Co Quinolone compounds
JPH0348682A (en) * 1989-07-14 1991-03-01 Yoshitomi Pharmaceut Ind Ltd Pyridonecarboxylic acid compound
JPH0366688A (en) * 1989-08-03 1991-03-22 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydro-4-oxonaphthyridine compound
DE3934082A1 (en) * 1989-10-12 1991-04-18 Bayer Ag CHINOLON CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN ANTIVIRAL AGENT

Also Published As

Publication number Publication date
KR100499366B1 (en) 2005-09-08
CA2211681C (en) 2003-05-13
AU5260096A (en) 1996-08-21
KR19980701781A (en) 1998-06-25
WO1996023775A1 (en) 1996-08-08

Similar Documents

Publication Publication Date Title
HUP9902714A2 (en) Novel pyridonecarboxylic acid derivatives or their salts and antibacterial agent comprising the same as the active ingredient
CA2160447A1 (en) Amino(thio)ether derivatives
EP0513387A4 (en) Active oxygen inhibitor
CA2311742A1 (en) 6-amino-9-benzyl-8-hydroxypurine derivatives
MX9606331A (en) Novel compound, process for producing the same, and antitumor agent.
MY105136A (en) Optically active pyridonecarboxylic acid derivatives.
ES2187473T3 (en) TRIARYLIMIDAZOLES.
EP1156045A4 (en) Amide derivatives and drug compositions
CA2171275A1 (en) Stilbene derivatives and pharmaceutical compositions containing them
NZ296594A (en) 1-(aminoalkylphenyl)guanidine and isothiourea derivatives
EP0787720A4 (en) Novel pyridonecarboxylate derivative or salt thereof and antibacterial containing the same as active ingredient
BR9407169A (en) Pyrazole derivatives
ATE170519T1 (en) CONDENSED HETEROCYLENE CONTAINING NITROGEN
AP9801321A0 (en) 2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-h-indole derivatives.
ZA916268B (en) Tricyclic compound or salts thereof,method for producing the same and antimicrobial agent containing the same
CA2327328A1 (en) Quinolonecarboxylic acid derivatives or salts thereof
AU3223801A (en) Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient
CA2211681A1 (en) Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient
ES2093091T3 (en) DERIVED FROM GLUTATION.
MY106904A (en) Herbicidal composition.
EP1134219A4 (en) Cycloalkyl-substituted aminomethylpyrrolidine derivatives
TW427993B (en) New cephem compounds
TW350840B (en) N-acylpiperazine derivative, antibacterial drug and anti-ulcer drug
EP0842931A4 (en) Oxopropionitrile derivatives and insect rest control agents
EP0702014A4 (en) DERIVATIVE DC-89

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed