CA2207025A1 - Utilisation d'additifs ajoutes a des agents contrastants pour ameliorer l'imagerie - Google Patents
Utilisation d'additifs ajoutes a des agents contrastants pour ameliorer l'imagerieInfo
- Publication number
- CA2207025A1 CA2207025A1 CA 2207025 CA2207025A CA2207025A1 CA 2207025 A1 CA2207025 A1 CA 2207025A1 CA 2207025 CA2207025 CA 2207025 CA 2207025 A CA2207025 A CA 2207025A CA 2207025 A1 CA2207025 A1 CA 2207025A1
- Authority
- CA
- Canada
- Prior art keywords
- inn
- stands
- nuclear
- ultrasonic
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- OINUMRGCICIETD-CGKNXJIZSA-N 3-[(e)-[(3as,4r,5r,6as)-4-[(e,3s)-3-cyclohexyl-3-hydroxyprop-1-enyl]-5-hydroxy-3,3a,4,5,6,6a-hexahydro-1h-pentalen-2-ylidene]methyl]benzoic acid Chemical compound C([C@H]1C[C@@H](O)[C@@H]([C@H]1C1)/C=C/[C@@H](O)C2CCCCC2)\C1=C/C1=CC=CC(C(O)=O)=C1 OINUMRGCICIETD-CGKNXJIZSA-N 0.000 claims description 2
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- ARUGKOZUKWAXDS-SEWALLKFSA-N cicaprost Chemical compound C1\C(=C/COCC(O)=O)C[C@@H]2[C@@H](C#C[C@@H](O)[C@@H](C)CC#CCC)[C@H](O)C[C@@H]21 ARUGKOZUKWAXDS-SEWALLKFSA-N 0.000 claims description 2
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- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 229960003104 ornithine Drugs 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000036593 pulmonary vascular resistance Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- ZEYOIOAKZLALAP-UHFFFAOYSA-M sodium amidotrizoate Chemical compound [Na+].CC(=O)NC1=C(I)C(NC(C)=O)=C(I)C(C([O-])=O)=C1I ZEYOIOAKZLALAP-UHFFFAOYSA-M 0.000 description 1
- 235000009518 sodium iodide Nutrition 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 description 1
- 230000009424 thromboembolic effect Effects 0.000 description 1
- 230000001732 thrombotic effect Effects 0.000 description 1
- RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 description 1
- JIVZKJJQOZQXQB-UHFFFAOYSA-N tolazoline Chemical compound C=1C=CC=CC=1CC1=NCCN1 JIVZKJJQOZQXQB-UHFFFAOYSA-N 0.000 description 1
- 229960002312 tolazoline Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000008359 toxicosis Effects 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/62—Unsaturated compounds containing ether groups, groups, groups, or groups containing rings other than six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention concerne l'utilisation de dérivés de prostacycline, ainsi que celle d'urée pour améliorer l'imagerie dans les diagnostics effectués par radiographie, ultrasons, résonance magnétique ou résonance magnétique nucléaire.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19944446694 DE4446694A1 (de) | 1994-12-09 | 1994-12-09 | Verwendung von Zusätzen zu Kontrastmitteln zur Verbesserung der Bildgebung |
| DEP4446694.3 | 1994-12-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2207025A1 true CA2207025A1 (fr) | 1996-06-13 |
Family
ID=6537194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2207025 Abandoned CA2207025A1 (fr) | 1994-12-09 | 1995-12-08 | Utilisation d'additifs ajoutes a des agents contrastants pour ameliorer l'imagerie |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0789594A1 (fr) |
| JP (1) | JPH10509691A (fr) |
| CA (1) | CA2207025A1 (fr) |
| DE (1) | DE4446694A1 (fr) |
| NO (1) | NO972613L (fr) |
| WO (1) | WO1996017629A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8257305B2 (en) | 2002-09-20 | 2012-09-04 | Bayer Pharma Aktiengesellschaft | Medical device for dispensing medicaments |
| US8389043B2 (en) | 2001-03-26 | 2013-03-05 | Bayer Pharma Aktiengesellschaft | Preparation for restenosis prevention |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE251893T1 (de) * | 1996-01-25 | 2003-11-15 | Schering Ag | Verbesserte kontrastmittenlösungen für die intravasale anwendung |
| EP1106177A4 (fr) * | 1999-06-14 | 2002-03-13 | Toray Industries | Composes facilitant l'accumulation de medicaments dans des tissus tumoraux |
| EP2324867B1 (fr) | 2002-07-12 | 2014-06-18 | Cook Medical Technologies LLC | Ballons d'angioplastie revêtis d'agents pharmaceutiques en forme expansée |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450149A (en) * | 1981-06-15 | 1984-05-22 | Research Corporation | Radiohalogenation method |
| JPH0669966B2 (ja) * | 1989-07-05 | 1994-09-07 | 株式会社ミドリ十字 | 血管造影補助剤 |
| US5334369A (en) * | 1991-06-11 | 1994-08-02 | Medical University Of South Carolina | Platelet receptor antagonists useful in detecting intravascular platelet aggregation |
| DE4135193C1 (fr) * | 1991-10-22 | 1993-03-11 | Schering Ag Berlin Und Bergkamen, 1000 Berlin, De |
-
1994
- 1994-12-09 DE DE19944446694 patent/DE4446694A1/de not_active Withdrawn
-
1995
- 1995-12-08 CA CA 2207025 patent/CA2207025A1/fr not_active Abandoned
- 1995-12-08 WO PCT/EP1995/004826 patent/WO1996017629A1/fr not_active Ceased
- 1995-12-08 EP EP95941697A patent/EP0789594A1/fr not_active Withdrawn
- 1995-12-08 JP JP8510449A patent/JPH10509691A/ja active Pending
-
1997
- 1997-06-06 NO NO972613A patent/NO972613L/no unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8389043B2 (en) | 2001-03-26 | 2013-03-05 | Bayer Pharma Aktiengesellschaft | Preparation for restenosis prevention |
| US9066990B2 (en) | 2001-03-26 | 2015-06-30 | Bayer Intellectual Property Gmbh | Preparation for restenosis prevention |
| US8257305B2 (en) | 2002-09-20 | 2012-09-04 | Bayer Pharma Aktiengesellschaft | Medical device for dispensing medicaments |
| US8439868B2 (en) | 2002-09-20 | 2013-05-14 | Bayer Pharma AG | Medical device for dispersing medicaments |
| US9649476B2 (en) | 2002-09-20 | 2017-05-16 | Bayer Intellectual Property Gmbh | Medical device for dispersing medicaments |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10509691A (ja) | 1998-09-22 |
| EP0789594A1 (fr) | 1997-08-20 |
| WO1996017629A1 (fr) | 1996-06-13 |
| DE4446694A1 (de) | 1996-06-13 |
| NO972613D0 (no) | 1997-06-06 |
| NO972613L (no) | 1997-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |