CA2206734A1 - Doseur de medicaments - Google Patents
Doseur de medicamentsInfo
- Publication number
- CA2206734A1 CA2206734A1 CA 2206734 CA2206734A CA2206734A1 CA 2206734 A1 CA2206734 A1 CA 2206734A1 CA 2206734 CA2206734 CA 2206734 CA 2206734 A CA2206734 A CA 2206734A CA 2206734 A1 CA2206734 A1 CA 2206734A1
- Authority
- CA
- Canada
- Prior art keywords
- fluid
- housing
- reservoir
- flow control
- stored energy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003814 drug Substances 0.000 title abstract description 48
- 239000012530 fluid Substances 0.000 claims abstract description 161
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract description 20
- 102000004877 Insulin Human genes 0.000 claims abstract description 10
- 108090001061 Insulin Proteins 0.000 claims abstract description 10
- 229940125396 insulin Drugs 0.000 claims abstract description 10
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 4
- 229940088710 antibiotic agent Drugs 0.000 claims abstract description 4
- 230000000174 oncolytic effect Effects 0.000 claims abstract description 4
- 229920000642 polymer Polymers 0.000 claims description 13
- 239000012528 membrane Substances 0.000 claims description 9
- 230000001413 cellular effect Effects 0.000 claims description 7
- -1 oncolytics Substances 0.000 claims description 6
- 239000006260 foam Substances 0.000 claims description 5
- 238000009826 distribution Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 238000001802 infusion Methods 0.000 claims description 4
- 229920000126 latex Polymers 0.000 claims description 4
- 239000000122 growth hormone Substances 0.000 claims description 2
- 238000007789 sealing Methods 0.000 claims 2
- 229940035676 analgesics Drugs 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 229920005570 flexible polymer Polymers 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 230000000149 penetrating effect Effects 0.000 claims 1
- 238000010276 construction Methods 0.000 description 27
- 239000000463 material Substances 0.000 description 19
- 125000006850 spacer group Chemical group 0.000 description 15
- 230000006870 function Effects 0.000 description 12
- 238000006073 displacement reaction Methods 0.000 description 8
- 229940079593 drug Drugs 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 229920001971 elastomer Polymers 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 239000004033 plastic Substances 0.000 description 5
- 229920003023 plastic Polymers 0.000 description 5
- 235000012431 wafers Nutrition 0.000 description 5
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 150000002500 ions Chemical class 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 239000005060 rubber Substances 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 229920002492 poly(sulfone) Polymers 0.000 description 3
- 239000004417 polycarbonate Substances 0.000 description 3
- 229920000515 polycarbonate Polymers 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 206010067484 Adverse reaction Diseases 0.000 description 2
- 229920002323 Silicone foam Polymers 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 230000006838 adverse reaction Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- GWUSZQUVEVMBPI-UHFFFAOYSA-N nimetazepam Chemical compound N=1CC(=O)N(C)C2=CC=C([N+]([O-])=O)C=C2C=1C1=CC=CC=C1 GWUSZQUVEVMBPI-UHFFFAOYSA-N 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 229920002725 thermoplastic elastomer Polymers 0.000 description 2
- 229920002803 thermoplastic polyurethane Polymers 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 101100205847 Mus musculus Srst gene Proteins 0.000 description 1
- 229920000459 Nitrile rubber Polymers 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920005830 Polyurethane Foam Polymers 0.000 description 1
- 229920006397 acrylic thermoplastic Polymers 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000012790 adhesive layer Substances 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 238000001595 flow curve Methods 0.000 description 1
- 239000006261 foam material Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000036449 good health Effects 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920001195 polyisoprene Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 239000011496 polyurethane foam Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000013514 silicone foam Substances 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Confectionery (AREA)
- Valve Device For Special Equipments (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Doseur (12) de médicaments injectables servant à débiter de façon régulière et contrôlable des médicaments liquides tels qu'insuline, antibiotiques, oncolytiques et produits semblables. Le doseur comporte une source d'énergie emmagasinée (36) consistant en une pièce en élastomère polymère déformable par compression qui fournit la force nécessaire pour produire un écoulement contrôlable du médicament versé à l'avance dans un récipient.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34949694A | 1994-12-02 | 1994-12-02 | |
| US08/349,496 | 1994-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2206734A1 true CA2206734A1 (fr) | 1996-06-06 |
Family
ID=23372647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2206734 Abandoned CA2206734A1 (fr) | 1994-12-02 | 1995-12-01 | Doseur de medicaments |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0796121A4 (fr) |
| JP (1) | JPH10510450A (fr) |
| AU (1) | AU704888B2 (fr) |
| CA (1) | CA2206734A1 (fr) |
| WO (1) | WO1996016691A1 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5743879A (en) * | 1994-12-02 | 1998-04-28 | Science Incorporated | Medicament dispenser |
| US5993421A (en) * | 1994-12-02 | 1999-11-30 | Science Incorporated | Medicament dispenser |
| CA2395349C (fr) * | 1999-12-23 | 2007-11-06 | Arnold Neracher | Dispositif d'injection et systeme de propulsion associe |
| DE20113761U1 (de) * | 2001-08-20 | 2001-12-20 | Lohmann & Rauscher GmbH & Co. KG, 56567 Neuwied | Wundversorgungsprodukt |
| US6802824B2 (en) * | 2002-06-17 | 2004-10-12 | Scimed Life Systems, Inc. | Catheter device and method for delivering a dose internally during minimally-invasive surgery |
| US20090062909A1 (en) | 2005-07-15 | 2009-03-05 | Micell Technologies, Inc. | Stent with polymer coating containing amorphous rapamycin |
| JP5756588B2 (ja) | 2005-07-15 | 2015-07-29 | ミセル テクノロジーズ、インコーポレイテッド | 制御されたモルホロジーの薬剤粉末を含むポリマーコーティング |
| US8852625B2 (en) | 2006-04-26 | 2014-10-07 | Micell Technologies, Inc. | Coatings containing multiple drugs |
| US11426494B2 (en) | 2007-01-08 | 2022-08-30 | MT Acquisition Holdings LLC | Stents having biodegradable layers |
| CN101711137B (zh) | 2007-01-08 | 2014-10-22 | 米歇尔技术公司 | 具有可生物降解层的支架 |
| SG192524A1 (en) | 2008-04-17 | 2013-08-30 | Micell Technologies Inc | Stents having bioabsorbable layers |
| CN102159257B (zh) | 2008-07-17 | 2015-11-25 | 米歇尔技术公司 | 药物递送医疗设备 |
| US9510856B2 (en) | 2008-07-17 | 2016-12-06 | Micell Technologies, Inc. | Drug delivery medical device |
| ES2850948T3 (es) * | 2008-12-09 | 2021-09-01 | Becton Dickinson Co | Sistema de administración de medicación de válvula abierta y cerrada para inyecciones de alta presión |
| US9981072B2 (en) | 2009-04-01 | 2018-05-29 | Micell Technologies, Inc. | Coated stents |
| CA2759015C (fr) | 2009-04-17 | 2017-06-20 | James B. Mcclain | Endoprotheses vasculaires ayant une elution controlee |
| CA2772686C (fr) * | 2009-09-23 | 2018-01-02 | Sanofi-Aventis Deutschland Gmbh | Ensemble et indicateur pour un dispositif de distribution de medicaments |
| EP2531140B1 (fr) | 2010-02-02 | 2017-11-01 | Micell Technologies, Inc. | Endoprothèse et système de pose d'endoprothèse avec une capacité améliorée de pose |
| US10232092B2 (en) | 2010-04-22 | 2019-03-19 | Micell Technologies, Inc. | Stents and other devices having extracellular matrix coating |
| CA2805631C (fr) | 2010-07-16 | 2018-07-31 | Micell Technologies, Inc. | Dispositif medical d'administration de medicament |
| CA2841360A1 (fr) | 2011-07-15 | 2013-01-24 | Micell Technologies, Inc. | Dispositif medical d'administration de medicament |
| ES2566179T5 (es) * | 2011-09-13 | 2019-11-14 | Unitract Syringe Pty Ltd | Conexión de paso de fluido estéril a envases de medicamento para bombas de liberación de medicamento |
| US10188772B2 (en) | 2011-10-18 | 2019-01-29 | Micell Technologies, Inc. | Drug delivery medical device |
| AU2014248508B2 (en) | 2013-03-12 | 2018-11-08 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
| US10272606B2 (en) | 2013-05-15 | 2019-04-30 | Micell Technologies, Inc. | Bioabsorbable biomedical implants |
| EP3380138A1 (fr) * | 2015-11-27 | 2018-10-03 | Sanofi-Aventis Deutschland GmbH | Dispositif d'injection à cavité expansible |
| US11318040B2 (en) | 2018-11-13 | 2022-05-03 | Contraline, Inc. | Systems and methods for delivering biomaterials |
| WO2024006163A2 (fr) * | 2022-06-27 | 2024-01-04 | Contraline, Inc. | Systèmes et procédés de distribution d'une composition |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE902776C (de) * | 1949-08-17 | 1954-01-28 | August Rooseboom | Selbsttaetiger Injektionsapparat mit Ampulle |
| US4209014A (en) * | 1977-12-12 | 1980-06-24 | Canadian Patents And Development Limited | Dispensing device for medicaments |
| DE3163728D1 (en) | 1980-04-08 | 1984-06-28 | Greater Glasgow Health Board | Dispensing device |
| US4592745A (en) | 1984-02-29 | 1986-06-03 | Novo Industri A/S | Dispenser |
| US4636197A (en) * | 1985-02-15 | 1987-01-13 | Ping Chu | Intravenous fluid infusion device |
| SE9301494D0 (sv) * | 1993-04-30 | 1993-04-30 | Kabi Pharmacia Ab | A device for dosing liquid preparation |
-
1995
- 1995-12-01 JP JP8519127A patent/JPH10510450A/ja active Pending
- 1995-12-01 EP EP95942976A patent/EP0796121A4/fr not_active Ceased
- 1995-12-01 AU AU44146/96A patent/AU704888B2/en not_active Ceased
- 1995-12-01 CA CA 2206734 patent/CA2206734A1/fr not_active Abandoned
- 1995-12-01 WO PCT/US1995/015715 patent/WO1996016691A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0796121A4 (fr) | 1998-08-26 |
| AU4414696A (en) | 1996-06-19 |
| EP0796121A1 (fr) | 1997-09-24 |
| AU704888B2 (en) | 1999-05-06 |
| WO1996016691A1 (fr) | 1996-06-06 |
| JPH10510450A (ja) | 1998-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |