CA2288649A1 - Formes de preparations pharmaceutiques stables pour peptides, proteines et acides nucleiques - Google Patents
Formes de preparations pharmaceutiques stables pour peptides, proteines et acides nucleiques Download PDFInfo
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- CA2288649A1 CA2288649A1 CA002288649A CA2288649A CA2288649A1 CA 2288649 A1 CA2288649 A1 CA 2288649A1 CA 002288649 A CA002288649 A CA 002288649A CA 2288649 A CA2288649 A CA 2288649A CA 2288649 A1 CA2288649 A1 CA 2288649A1
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- acids
- lyophilized preparations
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
L'invention a pour objet des préparations de biomolécules pharmaceutiques lyophilisées, stables au stockage, caractérisées en ce qu'elles renferment des biomolécules choisies dans le groupe comprenant des protéines, peptides, acides nucléiques et hydrates de carbone; un ou plusieurs aminoacides D ou L basiques, ainsi qu'un ou plusieurs acides aminodicarboxyliques, hydroxycarboxyliques ou dicarboxyliques, ou leurs sels physiologiquement compatibles. Les substances auxiliaires se présentent, dans le lyophilisat, en totalité ou en partie sous forme amorphe.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19716154.5 | 1997-04-18 | ||
| DE19716154A DE19716154A1 (de) | 1997-04-18 | 1997-04-18 | Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren |
| PCT/EP1998/002131 WO1998047490A1 (fr) | 1997-04-18 | 1998-04-11 | Formes de preparations pharmaceutiques stables pour peptides, proteines et acides nucleiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2288649A1 true CA2288649A1 (fr) | 1998-10-29 |
Family
ID=7826847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002288649A Abandoned CA2288649A1 (fr) | 1997-04-18 | 1998-04-11 | Formes de preparations pharmaceutiques stables pour peptides, proteines et acides nucleiques |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0975335A1 (fr) |
| JP (1) | JP2001524090A (fr) |
| KR (1) | KR20010006562A (fr) |
| CN (1) | CN1261271A (fr) |
| AU (1) | AU744777B2 (fr) |
| BR (1) | BR9809103A (fr) |
| CA (1) | CA2288649A1 (fr) |
| DE (1) | DE19716154A1 (fr) |
| TR (1) | TR199902575T2 (fr) |
| WO (1) | WO1998047490A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7276359B1 (en) | 1998-03-13 | 2007-10-02 | Wyeth | Polynucleotide composition, method of preparation, and use thereof |
| ES2239440T3 (es) * | 1998-03-13 | 2005-09-16 | Wyeth | Composicion polinucleotidica, procedimiento para la preparacion y utilizacion de la misma. |
| EP1555033A3 (fr) * | 1998-03-13 | 2005-08-17 | Wyeth | Composition polynucléotidique, procédé de préparation et utilisation |
| DE19840531C2 (de) * | 1998-08-28 | 2003-05-15 | Roboscreen Ges Fuer Molekulare | Mit Nukleinsäuren beschichtete Reaktionsräume, Verfahren zu ihrer Herstellung und ihre Verwendung |
| KR100767473B1 (ko) * | 1999-05-31 | 2007-10-17 | 미쯔비시 가가꾸 가부시끼가이샤 | 간실질세포 증식인자 동결건조 제제 |
| DE10149030A1 (de) * | 2001-10-05 | 2003-04-10 | Viscum Ag | Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin |
| JP2007501224A (ja) * | 2003-08-05 | 2007-01-25 | フジ フォト フィルム ビー．ブイ． | 安定剤としての組換え又は合成ゼラチン様タンパク質の、凍結乾燥医薬組成物中の使用 |
| WO2005116081A2 (fr) * | 2004-05-24 | 2005-12-08 | Genvault Corporation | Stockage proteique stable et stockage d'acides nucleiques stable sous forme recuperable |
| GB0517688D0 (en) * | 2005-08-31 | 2005-10-05 | Cambridge Biostability Ltd | Improvements in the stabilisation of biological materials |
| EP2234603A1 (fr) * | 2007-12-19 | 2010-10-06 | EKR Therapeutics, Inc. | Préparations de peptide natriurétique lyophilisé, stables à température ambiante |
| WO2010031007A2 (fr) | 2008-09-12 | 2010-03-18 | Genvault Corporation | Matrices et support pour le stockage et la stabilisation de biomolécules |
| JP2016109911A (ja) | 2014-12-08 | 2016-06-20 | 三星ディスプレイ株式會社Ｓａｍｓｕｎｇ Ｄｉｓｐｌａｙ Ｃｏ．，Ｌｔｄ． | 表示装置、表示方法、及びプログラム |
| JP2016109914A (ja) | 2014-12-08 | 2016-06-20 | 三星ディスプレイ株式會社Ｓａｍｓｕｎｇ Ｄｉｓｐｌａｙ Ｃｏ．，Ｌｔｄ． | 表示装置、表示方法、及びプログラム |
| KR102369835B1 (ko) | 2014-12-08 | 2022-03-04 | 삼성디스플레이 주식회사 | 표시 장치 및 표시 방법 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63115822A (ja) * | 1986-11-04 | 1988-05-20 | Teijin Ltd | 生理活性ポリペプチド類の経鼻投与用粉末状組成物 |
| DE3729863A1 (de) * | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
| DE4126983A1 (de) * | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke |
| DE4126984A1 (de) * | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, gut vertraeglichen arzneimitteln fuer infusions- oder injektionszwecke |
| DE19538687A1 (de) * | 1995-10-17 | 1997-04-24 | Boehringer Mannheim Gmbh | Stabile pharmazeutische Darreichungsformen enthaltend Parathormon |
-
1997
- 1997-04-18 DE DE19716154A patent/DE19716154A1/de not_active Withdrawn
-
1998
- 1998-04-11 JP JP54494698A patent/JP2001524090A/ja active Pending
- 1998-04-11 BR BR9809103-4A patent/BR9809103A/pt not_active IP Right Cessation
- 1998-04-11 CN CN98806448A patent/CN1261271A/zh active Pending
- 1998-04-11 CA CA002288649A patent/CA2288649A1/fr not_active Abandoned
- 1998-04-11 EP EP98925470A patent/EP0975335A1/fr not_active Withdrawn
- 1998-04-11 AU AU77585/98A patent/AU744777B2/en not_active Ceased
- 1998-04-11 WO PCT/EP1998/002131 patent/WO1998047490A1/fr not_active Ceased
- 1998-04-11 KR KR1019997009652A patent/KR20010006562A/ko not_active Ceased
- 1998-04-11 TR TR1999/02575T patent/TR199902575T2/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001524090A (ja) | 2001-11-27 |
| BR9809103A (pt) | 2000-08-01 |
| DE19716154A1 (de) | 1998-10-22 |
| KR20010006562A (ko) | 2001-01-26 |
| WO1998047490A1 (fr) | 1998-10-29 |
| TR199902575T2 (xx) | 2000-02-21 |
| EP0975335A1 (fr) | 2000-02-02 |
| AU7758598A (en) | 1998-11-13 |
| CN1261271A (zh) | 2000-07-26 |
| AU744777B2 (en) | 2002-03-07 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Dead |