CA2279490A1 - Glutrnagln amidotransferase: un nouveau composant essentiel de la traduction - Google Patents
Glutrnagln amidotransferase: un nouveau composant essentiel de la traduction Download PDFInfo
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- CA2279490A1 CA2279490A1 CA002279490A CA2279490A CA2279490A1 CA 2279490 A1 CA2279490 A1 CA 2279490A1 CA 002279490 A CA002279490 A CA 002279490A CA 2279490 A CA2279490 A CA 2279490A CA 2279490 A1 CA2279490 A1 CA 2279490A1
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- adt
- seq
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- polynucleotide
- polypeptide
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- 238000000527 sonication Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 210000004989 spleen cell Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000001308 synthesis method Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 108010061238 threonyl-glycine Proteins 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
- 108010080629 tryptophan-leucine Proteins 0.000 description 1
- 108010035534 tyrosyl-leucyl-alanine Proteins 0.000 description 1
- 230000009452 underexpressoin Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Le présent procédé a pour objet la séquence d'acides aminés et la séquence nucléotidique codante de la GlutRNAGln amidotransférase (AdT), une protéine essentielle à la traduction des protéines. Les protéines AdT et les molécules d'acide nucléique codantes décrites peuvent être utilisées pour identifier des agents bloquant les traductions. De tels agents peuvent s'utiliser comme agent antimicrobien, antifongique, ou herbicide.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3727597P | 1997-02-03 | 1997-02-03 | |
| US60/037,275 | 1997-02-03 | ||
| PCT/US1998/001860 WO1998033925A1 (fr) | 1997-02-03 | 1998-02-03 | Glutrnagln amidotransferase: un nouveau composant essentiel de la traduction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2279490A1 true CA2279490A1 (fr) | 1998-08-06 |
Family
ID=21893461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002279490A Abandoned CA2279490A1 (fr) | 1997-02-03 | 1998-02-03 | Glutrnagln amidotransferase: un nouveau composant essentiel de la traduction |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1015602A1 (fr) |
| JP (1) | JP2001511004A (fr) |
| AU (1) | AU6259198A (fr) |
| CA (1) | CA2279490A1 (fr) |
| WO (1) | WO1998033925A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999018239A1 (fr) * | 1997-10-02 | 1999-04-15 | Smithkline Beecham Corporation | Criblage de medicaments antimicrobiens au moyen d'une cellule recombinee renfermant un gene d'amidotransferase dependant de l'arn |
| DE19949000A1 (de) * | 1999-10-11 | 2001-04-12 | Basf Ag | PRPP-Amidotransferase aus Pflanzen |
| WO2002000703A2 (fr) * | 2000-06-27 | 2002-01-03 | Bayer Aktiengesellschaft | Regulation de l'enzyme de type glutamyl-arnt (gln) amido-transferase humaine |
| WO2003078613A2 (fr) | 2002-03-20 | 2003-09-25 | Basf Aktiengesellschaft | Serine hydroxymethyltransferase en tant que cible d'herbicides |
| JP2007516704A (ja) | 2003-12-02 | 2007-06-28 | ビーエーエスエフ アクチェンゲゼルシャフト | 除草剤の標的としての2−メチル−6−ソラニルベンゾキノン・メチルトランスフェラーゼ |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0191221A1 (fr) * | 1984-10-24 | 1986-08-20 | The Regents Of The University Of California | Vecteurs pour la transformation d'ascomycètes |
| US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
-
1998
- 1998-02-03 CA CA002279490A patent/CA2279490A1/fr not_active Abandoned
- 1998-02-03 EP EP98904799A patent/EP1015602A1/fr not_active Withdrawn
- 1998-02-03 JP JP53313298A patent/JP2001511004A/ja active Pending
- 1998-02-03 WO PCT/US1998/001860 patent/WO1998033925A1/fr not_active Ceased
- 1998-02-03 AU AU62591/98A patent/AU6259198A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6259198A (en) | 1998-08-25 |
| WO1998033925A1 (fr) | 1998-08-06 |
| JP2001511004A (ja) | 2001-08-07 |
| EP1015602A1 (fr) | 2000-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |