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CA2124358A1 - Nouvelles proteases ayant une activite de fragmentation de l'adn - Google Patents

Nouvelles proteases ayant une activite de fragmentation de l'adn

Info

Publication number
CA2124358A1
CA2124358A1 CA002124358A CA2124358A CA2124358A1 CA 2124358 A1 CA2124358 A1 CA 2124358A1 CA 002124358 A CA002124358 A CA 002124358A CA 2124358 A CA2124358 A CA 2124358A CA 2124358 A1 CA2124358 A1 CA 2124358A1
Authority
CA
Canada
Prior art keywords
protease
fragmentin
dna
composition
granule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002124358A
Other languages
English (en)
Inventor
Arnold H. Greenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Manitoba
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2124358A1 publication Critical patent/CA2124358A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6467—Granzymes, e.g. granzyme A (3.4.21.78); granzyme B (3.4.21.79)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002124358A 1991-11-25 1992-11-25 Nouvelles proteases ayant une activite de fragmentation de l'adn Abandoned CA2124358A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919124986A GB9124986D0 (en) 1991-11-25 1991-11-25 Natural killer cell granule protein
GB9124986.2 1991-11-25
PCT/CA1992/000515 WO1993011246A1 (fr) 1991-11-25 1992-11-25 Nouvelles proteases a activite de fragmentation de l'adn

Publications (1)

Publication Number Publication Date
CA2124358A1 true CA2124358A1 (fr) 1993-06-10

Family

ID=10705175

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002124358A Abandoned CA2124358A1 (fr) 1991-11-25 1992-11-25 Nouvelles proteases ayant une activite de fragmentation de l'adn

Country Status (7)

Country Link
EP (1) EP0615548A1 (fr)
JP (1) JPH07504806A (fr)
KR (1) KR940703919A (fr)
AU (1) AU678758B2 (fr)
CA (1) CA2124358A1 (fr)
GB (1) GB9124986D0 (fr)
WO (1) WO1993011246A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087160A (en) * 1993-06-24 2000-07-11 The General Hospital Corporation Programmed cell death genes and proteins
WO1995000160A1 (fr) * 1993-06-24 1995-01-05 The General Hospital Corporation Genes regulateurs de la mort cellulaire programmee et proteines
US5952189A (en) * 1994-06-10 1999-09-14 Panorama Research, Inc. Assay for inhibitors of a 24 kD cytoplasmic protease which activates DNA fragmentation in apoptosis
US5605826A (en) * 1994-06-10 1997-02-25 Panorama Research, Inc. 24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis

Also Published As

Publication number Publication date
WO1993011246A1 (fr) 1993-06-10
JPH07504806A (ja) 1995-06-01
AU2939092A (en) 1993-06-28
AU678758B2 (en) 1997-06-12
GB9124986D0 (en) 1992-01-22
KR940703919A (ko) 1994-12-12
EP0615548A1 (fr) 1994-09-21

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead