CA2117367A1 - 3-phenylureidoazepin-2-ones et benzazepin-2-ones utiles comme antagonistes de la cholecystokinine - Google Patents
3-phenylureidoazepin-2-ones et benzazepin-2-ones utiles comme antagonistes de la cholecystokinineInfo
- Publication number
- CA2117367A1 CA2117367A1 CA002117367A CA2117367A CA2117367A1 CA 2117367 A1 CA2117367 A1 CA 2117367A1 CA 002117367 A CA002117367 A CA 002117367A CA 2117367 A CA2117367 A CA 2117367A CA 2117367 A1 CA2117367 A1 CA 2117367A1
- Authority
- CA
- Canada
- Prior art keywords
- oxo
- phenyl
- ureido
- nmr
- cdci3
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82567792A | 1992-01-27 | 1992-01-27 | |
| US825,677 | 1992-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2117367A1 true CA2117367A1 (fr) | 1993-08-05 |
Family
ID=25244657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002117367A Abandoned CA2117367A1 (fr) | 1992-01-27 | 1992-12-16 | 3-phenylureidoazepin-2-ones et benzazepin-2-ones utiles comme antagonistes de la cholecystokinine |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0625145A1 (fr) |
| JP (1) | JPH07503465A (fr) |
| KR (1) | KR950700257A (fr) |
| CN (1) | CN1074903A (fr) |
| AU (1) | AU3276193A (fr) |
| BR (1) | BR9207071A (fr) |
| CA (1) | CA2117367A1 (fr) |
| CZ (1) | CZ391092A3 (fr) |
| FI (1) | FI943513A7 (fr) |
| HU (1) | HUT70496A (fr) |
| IL (1) | IL104472A0 (fr) |
| MX (1) | MX9300409A (fr) |
| NO (1) | NO942775L (fr) |
| NZ (1) | NZ245759A (fr) |
| RU (1) | RU94038063A (fr) |
| TW (1) | TW213901B (fr) |
| WO (1) | WO1993015059A1 (fr) |
| YU (1) | YU4393A (fr) |
| ZA (1) | ZA93582B (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2097688A1 (es) * | 1993-07-14 | 1997-04-01 | Pfizer | Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas. |
| DE69419157T2 (de) * | 1993-07-26 | 1999-10-14 | Pfizer Inc. | Tetrahydro-1h-benzazepinone und hexahydro azepinone als selektive cholecystokinin-b rezeptor antagonisten |
| US5453424A (en) * | 1993-11-22 | 1995-09-26 | Merck & Co., Inc. | Furanodiazepines |
| WO1995014671A1 (fr) * | 1993-11-22 | 1995-06-01 | Merck & Co., Inc. | 3-acylaminobenzazepines |
| US5977355A (en) * | 1994-10-04 | 1999-11-02 | Pfizer Inc. | Processes and intermediates for preparing 3-amino-benzo(b)azepinones |
| ES2171196T3 (es) * | 1994-10-14 | 2002-09-01 | Glaxosmithkline Spa | Uso de antagonistas del receptor cck-b para el tratamiento de trastornos del sueño. |
| DE10153348A1 (de) | 2001-10-29 | 2003-05-08 | Gruenenthal Gmbh | Substituierte Benzo(b)azepin-2-on-Verbindungen |
| AU2006342209A1 (en) * | 2005-06-16 | 2007-10-25 | Novartis Ag | Lactam containing HCV inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0166357A3 (fr) * | 1984-06-26 | 1988-10-26 | Merck & Co. Inc. | Benzo-lactames condensés et leurs compositions pharmaceutiques |
| US4767756A (en) * | 1987-07-17 | 1988-08-30 | E. R. Squibb & Sons, Inc. | 3-substituted benzazepines |
| EP0322779A3 (fr) * | 1987-12-29 | 1991-05-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Composés de benzolactame et leur utilisation pharmaceutique |
| US5206234A (en) * | 1990-10-22 | 1993-04-27 | Merck & Co., Inc. | Benzolactam analogs as antagonists of cck |
-
1992
- 1992-12-15 TW TW081110044A patent/TW213901B/zh active
- 1992-12-16 AU AU32761/93A patent/AU3276193A/en not_active Abandoned
- 1992-12-16 EP EP93901470A patent/EP0625145A1/fr not_active Withdrawn
- 1992-12-16 CA CA002117367A patent/CA2117367A1/fr not_active Abandoned
- 1992-12-16 RU RU94038063/04A patent/RU94038063A/ru unknown
- 1992-12-16 KR KR1019940702565A patent/KR950700257A/ko not_active Ceased
- 1992-12-16 FI FI943513A patent/FI943513A7/fi unknown
- 1992-12-16 JP JP5513196A patent/JPH07503465A/ja active Pending
- 1992-12-16 HU HU9402195A patent/HUT70496A/hu unknown
- 1992-12-16 WO PCT/US1992/010720 patent/WO1993015059A1/fr not_active Ceased
- 1992-12-16 BR BR9207071A patent/BR9207071A/pt not_active Application Discontinuation
- 1992-12-28 CZ CS923910A patent/CZ391092A3/cs unknown
-
1993
- 1993-01-21 CN CN93101158A patent/CN1074903A/zh active Pending
- 1993-01-21 IL IL104472A patent/IL104472A0/xx unknown
- 1993-01-26 NZ NZ245759A patent/NZ245759A/en unknown
- 1993-01-26 YU YU4393A patent/YU4393A/sh unknown
- 1993-01-26 MX MX9300409A patent/MX9300409A/es unknown
- 1993-01-27 ZA ZA93582A patent/ZA93582B/xx unknown
-
1994
- 1994-07-26 NO NO942775A patent/NO942775L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1993015059A1 (fr) | 1993-08-05 |
| FI943513A0 (fi) | 1994-07-26 |
| MX9300409A (es) | 1993-07-01 |
| HUT70496A (en) | 1995-10-30 |
| EP0625145A1 (fr) | 1994-11-23 |
| CN1074903A (zh) | 1993-08-04 |
| HU9402195D0 (en) | 1994-09-28 |
| NO942775D0 (no) | 1994-07-26 |
| NZ245759A (en) | 1997-06-24 |
| CZ391092A3 (en) | 1994-01-19 |
| JPH07503465A (ja) | 1995-04-13 |
| KR950700257A (ko) | 1995-01-16 |
| TW213901B (fr) | 1993-10-01 |
| FI943513L (fi) | 1994-07-26 |
| YU4393A (sr) | 1996-01-09 |
| IL104472A0 (en) | 1993-05-13 |
| BR9207071A (pt) | 1995-12-05 |
| AU3276193A (en) | 1993-09-01 |
| NO942775L (no) | 1994-09-20 |
| RU94038063A (ru) | 1996-05-27 |
| ZA93582B (en) | 1994-07-27 |
| FI943513A7 (fi) | 1994-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |