CA2104372A1 - Sels stables d'acides (+)-(1s,2r-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxyliques, procede d'obtention et compositions pharmaceutiques qui en contiennent - Google Patents

Sels stables d'acides (+)-(1s,2r-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxyliques, procede d'obtention et compositions pharmaceutiques qui en contiennent

Info

Publication number: CA2104372A1
Authority: CA; Canada
Prior art keywords: oxoethyl; carbonyl; carboxylic acid; alkaline; hydroxylamino
Prior art date: 1991-12-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002104372A

Other languages

English (en)

Inventor

Raffaello Giorgi

Alessandro Subissi

Luigi Turbanti

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Laboratorio Guidotti SpA

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-23

Filing date

1992-12-12

Publication date

1993-06-24

1992-12-12 Application filed by Individual filed Critical Individual

1993-06-24 Publication of CA2104372A1 publication Critical patent/CA2104372A1/fr

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

CA002104372A 1991-12-23 1992-12-12 Sels stables d'acides (+)-(1s,2r-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino|carbonyl|cyclohexane-1-carboxyliques, procede d'obtention et compositions pharmaceutiques qui en contiennent Abandoned CA2104372A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ITMI913448A IT1252708B (it)	1991-12-23	1991-12-23	Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
ITMI91A003448		1991-12-23

Publications (1)

Publication Number	Publication Date
CA2104372A1 true CA2104372A1 (fr)	1993-06-24

Family

ID=11361409

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002104372A Abandoned CA2104372A1 (fr)	1991-12-23	1992-12-12	Sels stables d'acides (+)-(1s,2r-¬¬n-(2-hydroxylamino-2-oxoethyl) -n-methyl-amino\|carbonyl\|cyclohexane-1-carboxyliques, procede d'obtention et compositions pharmaceutiques qui en contiennent

Country Status (26)

Country	Link
EP (1)	EP0575572A1 (fr)
JP (1)	JPH06506002A (fr)
CN (1)	CN1079474A (fr)
AU (1)	AU657591B2 (fr)
BG (1)	BG98050A (fr)
BR (1)	BR9205652A (fr)
CA (1)	CA2104372A1 (fr)
CZ (1)	CZ379692A3 (fr)
EE (1)	EE9400006A (fr)
FI (1)	FI933685L (fr)
HR (1)	HRP921454A2 (fr)
HU (1)	HUT69287A (fr)
IT (1)	IT1252708B (fr)
LV (1)	LV10426B (fr)
MA (1)	MA22749A1 (fr)
MX (1)	MX9207543A (fr)
NZ (1)	NZ245547A (fr)
PL (1)	PL169086B1 (fr)
PT (1)	PT101156A (fr)
RU (1)	RU2079489C1 (fr)
SI (1)	SI9200409A (fr)
SK (1)	SK379692A3 (fr)
TN (1)	TNSN92117A1 (fr)
WO (1)	WO1993013056A1 (fr)
YU (1)	YU110892A (fr)
ZA (1)	ZA9210004B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1264860B1 (it) *	1993-06-21	1996-10-17	Guidotti & C Spa Labor	Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici
US5639746A (en) *	1994-12-29	1997-06-17	The Procter & Gamble Company	Hydroxamic acid-containing inhibitors of matrix metalloproteases
FR2817241B1 (fr)	2000-11-30	2003-03-07	Cebal	Tube aluminium avec embout secable
CN101516191A (zh) *	2006-09-28	2009-08-26	默克公司	Saha的胺碱盐和其多晶型物
EP4166048B1 (fr)	2020-04-27	2024-12-25	Carter-Hoffmann, LLC	Système de déplacement de porte pour armoire

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1224627B (it) *	1988-04-12	1990-10-04	Guidotti & C Spa Labor	Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono.

1991
- 1991-12-23 IT ITMI913448A patent/IT1252708B/it active IP Right Grant
1992
- 1992-12-12 CA CA002104372A patent/CA2104372A1/fr not_active Abandoned
- 1992-12-12 AU AU30871/92A patent/AU657591B2/en not_active Ceased
- 1992-12-12 RU RU9293052414A patent/RU2079489C1/ru active
- 1992-12-12 EP EP92924726A patent/EP0575572A1/fr not_active Withdrawn
- 1992-12-12 HU HU9302389A patent/HUT69287A/hu unknown
- 1992-12-12 JP JP5511398A patent/JPH06506002A/ja active Pending
- 1992-12-12 FI FI933685A patent/FI933685L/fi not_active Application Discontinuation
- 1992-12-12 WO PCT/EP1992/002903 patent/WO1993013056A1/fr not_active Ceased
- 1992-12-12 BR BR9205652A patent/BR9205652A/pt not_active Application Discontinuation
- 1992-12-21 CZ CS923796A patent/CZ379692A3/cs unknown
- 1992-12-21 SK SK3796-92A patent/SK379692A3/sk unknown
- 1992-12-21 NZ NZ245547A patent/NZ245547A/en unknown
- 1992-12-22 HR HR921454A patent/HRP921454A2/hr not_active Application Discontinuation
- 1992-12-22 MA MA23040A patent/MA22749A1/fr unknown
- 1992-12-22 SI SI9200409A patent/SI9200409A/sl unknown
- 1992-12-23 PL PL92297118A patent/PL169086B1/pl unknown
- 1992-12-23 LV LVP-92-358A patent/LV10426B/lv unknown
- 1992-12-23 YU YU110892A patent/YU110892A/sh unknown
- 1992-12-23 ZA ZA9210004A patent/ZA9210004B/xx unknown
- 1992-12-23 TN TNTNSN92117A patent/TNSN92117A1/fr unknown
- 1992-12-23 PT PT101156A patent/PT101156A/pt not_active Application Discontinuation
- 1992-12-23 CN CN92113839A patent/CN1079474A/zh active Pending
- 1992-12-23 MX MX9207543A patent/MX9207543A/es unknown
1993
- 1993-08-18 BG BG98050A patent/BG98050A/bg unknown
1994
- 1994-05-23 EE EE9400006A patent/EE9400006A/xx unknown

Also Published As

Publication number	Publication date
EE9400006A (et)	1995-12-15
FI933685A0 (fi)	1993-08-20
PL169086B1 (pl)	1996-05-31
NZ245547A (en)	1995-12-21
HUT69287A (en)	1995-09-28
RU2079489C1 (ru)	1997-05-20
BR9205652A (pt)	1994-05-03
CZ379692A3 (en)	1993-09-15
AU657591B2 (en)	1995-03-16
HRP921454A2 (en)	1995-02-28
PL297118A1 (en)	1993-09-06
SI9200409A (en)	1993-09-30
TNSN92117A1 (fr)	1993-06-08
YU110892A (sh)	1996-01-08
AU3087192A (en)	1993-07-28
SK379692A3 (en)	1995-04-12
WO1993013056A1 (fr)	1993-07-08
LV10426A (lv)	1995-02-20
JPH06506002A (ja)	1994-07-07
ITMI913448A0 (it)	1991-12-23
MA22749A1 (fr)	1993-07-01
ITMI913448A1 (it)	1993-06-23
HU9302389D0 (en)	1993-11-29
EP0575572A1 (fr)	1993-12-29
FI933685A7 (fi)	1993-08-20
PT101156A (pt)	1994-06-30
MX9207543A (es)	1993-08-01
FI933685L (fi)	1993-08-20
CN1079474A (zh)	1993-12-15
LV10426B (en)	1995-08-20
ZA9210004B (en)	1993-12-13
BG98050A (bg)	1994-04-29
IT1252708B (it)	1995-06-26

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Legal Events

Date	Code	Title	Description
1997-12-12	FZDE	Discontinued