CA2195867A1 - Membrane destinee a la regeneration de tissus du corps et son utilisation sous forme de couverture de plaie et de peau de remplacement - Google Patents
Membrane destinee a la regeneration de tissus du corps et son utilisation sous forme de couverture de plaie et de peau de remplacementInfo
- Publication number
- CA2195867A1 CA2195867A1 CA 2195867 CA2195867A CA2195867A1 CA 2195867 A1 CA2195867 A1 CA 2195867A1 CA 2195867 CA2195867 CA 2195867 CA 2195867 A CA2195867 A CA 2195867A CA 2195867 A1 CA2195867 A1 CA 2195867A1
- Authority
- CA
- Canada
- Prior art keywords
- membrane
- fact
- membrane according
- process according
- impression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 69
- 230000001172 regenerating effect Effects 0.000 title abstract 2
- 239000007789 gas Substances 0.000 claims abstract description 4
- 229920002521 macromolecule Polymers 0.000 claims abstract description 4
- 239000000560 biocompatible material Substances 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims description 27
- 210000004027 cell Anatomy 0.000 claims description 21
- 210000001519 tissue Anatomy 0.000 claims description 16
- 210000003491 skin Anatomy 0.000 claims description 11
- 238000004049 embossing Methods 0.000 claims description 10
- 229920001577 copolymer Polymers 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000002184 metal Substances 0.000 claims description 6
- 239000011505 plaster Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 5
- 229920000954 Polyglycolide Polymers 0.000 claims description 4
- 239000000835 fiber Substances 0.000 claims description 4
- 229910052602 gypsum Inorganic materials 0.000 claims description 4
- 239000010440 gypsum Substances 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 239000011148 porous material Substances 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 230000008929 regeneration Effects 0.000 claims description 3
- 238000011069 regeneration method Methods 0.000 claims description 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims description 2
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- 230000028327 secretion Effects 0.000 claims description 2
- 210000004207 dermis Anatomy 0.000 claims 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
- 229920002674 hyaluronan Polymers 0.000 claims 2
- 229960003160 hyaluronic acid Drugs 0.000 claims 2
- 239000004633 polyglycolic acid Substances 0.000 claims 2
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical compound O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims 2
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 239000006285 cell suspension Substances 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 239000003431 cross linking reagent Substances 0.000 claims 1
- 230000032050 esterification Effects 0.000 claims 1
- 238000005886 esterification reaction Methods 0.000 claims 1
- 210000002510 keratinocyte Anatomy 0.000 claims 1
- 238000010147 laser engraving Methods 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims 1
- 229920002627 poly(phosphazenes) Polymers 0.000 claims 1
- 229920002492 poly(sulfone) Polymers 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 239000004632 polycaprolactone Substances 0.000 claims 1
- 239000000622 polydioxanone Substances 0.000 claims 1
- 229920002635 polyurethane Polymers 0.000 claims 1
- 239000004814 polyurethane Substances 0.000 claims 1
- 238000003825 pressing Methods 0.000 claims 1
- 238000007390 skin biopsy Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
- 210000004379 membrane Anatomy 0.000 description 16
- 150000002500 ions Chemical class 0.000 description 12
- 206010052428 Wound Diseases 0.000 description 10
- 208000027418 Wounds and injury Diseases 0.000 description 10
- 239000000499 gel Substances 0.000 description 4
- 101100257011 Mus musculus Skil gene Proteins 0.000 description 3
- 229910000831 Steel Inorganic materials 0.000 description 3
- 239000010959 steel Substances 0.000 description 3
- 241000100287 Membras Species 0.000 description 2
- 241000164466 Palaemon adspersus Species 0.000 description 2
- 241000183024 Populus tremula Species 0.000 description 2
- 101150007148 THI5 gene Proteins 0.000 description 2
- 238000001574 biopsy Methods 0.000 description 2
- 210000002950 fibroblast Anatomy 0.000 description 2
- -1 polylactiae Polymers 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 241000894007 species Species 0.000 description 2
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 1
- BSFODEXXVBBYOC-UHFFFAOYSA-N 8-[4-(dimethylamino)butan-2-ylamino]quinolin-6-ol Chemical compound C1=CN=C2C(NC(CCN(C)C)C)=CC(O)=CC2=C1 BSFODEXXVBBYOC-UHFFFAOYSA-N 0.000 description 1
- 241001550206 Colla Species 0.000 description 1
- 241000501458 Cultus Species 0.000 description 1
- 241001406277 Darna Species 0.000 description 1
- 101100536354 Drosophila melanogaster tant gene Proteins 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 241000370541 Idia Species 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- 241000353097 Molva molva Species 0.000 description 1
- 101100400378 Mus musculus Marveld2 gene Proteins 0.000 description 1
- 101100345589 Mus musculus Mical1 gene Proteins 0.000 description 1
- CCFQLQIYEHITNK-UHFFFAOYSA-N Polycarpol Natural products CC1(C)C(O)CCC2(C)C3=CCC4(C)C(C(CCC=C(C)C)C)CC(O)C4(C)C3=CCC21 CCFQLQIYEHITNK-UHFFFAOYSA-N 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 102100034742 Rotatin Human genes 0.000 description 1
- 101710200213 Rotatin Proteins 0.000 description 1
- 235000018734 Sambucus australis Nutrition 0.000 description 1
- 244000180577 Sambucus australis Species 0.000 description 1
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 1
- 102100035115 Testin Human genes 0.000 description 1
- 101710070533 Testin Proteins 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- PXUQTDZNOHRWLI-OXUVVOBNSA-O malvidin 3-O-beta-D-glucoside Chemical compound COC1=C(O)C(OC)=CC(C=2C(=CC=3C(O)=CC(O)=CC=3[O+]=2)O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)=C1 PXUQTDZNOHRWLI-OXUVVOBNSA-O 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000004927 skin cell Anatomy 0.000 description 1
- HJHVQCXHVMGZNC-JCJNLNMISA-M sodium;(2z)-2-[(3r,4s,5s,8s,9s,10s,11r,13r,14s,16s)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoate Chemical compound [Na+].O[C@@H]([C@@H]12)C[C@H]3\C(=C(/CCC=C(C)C)C([O-])=O)[C@@H](OC(C)=O)C[C@]3(C)[C@@]2(C)CC[C@@H]2[C@]1(C)CC[C@@H](O)[C@H]2C HJHVQCXHVMGZNC-JCJNLNMISA-M 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/023—Adhesive bandages or dressings wound covering film layers without a fluid retention layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
- A61F2/105—Skin implants, e.g. artificial skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
- C12N5/0698—Skin equivalents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1323—Adult fibroblasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Wood Science & Technology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Cardiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
L'invention concerne une membrane destinée à la régénération de tissus du corps, constituée d'un matériau biocompatible et caractérisée par la combinaison des caractéristiques suivantes: épaisseur comprise entre 0,5 et 500 microns; perméabilité aux gaz et macromolécules, imperméabilité aux cellules, microstructure en forme de bosses (16) et/ou de creux (14).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4426315.5 | 1994-07-25 | ||
| DE19944426315 DE4426315C1 (de) | 1994-07-25 | 1994-07-25 | Membran zur Regeneration von Körpergeweben und Verwendung der Membran als Wundabdeckung und Hautersatz |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2195867A1 true CA2195867A1 (fr) | 1996-02-08 |
Family
ID=6524093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2195867 Abandoned CA2195867A1 (fr) | 1994-07-25 | 1995-07-20 | Membrane destinee a la regeneration de tissus du corps et son utilisation sous forme de couverture de plaie et de peau de remplacement |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0772425A1 (fr) |
| AU (1) | AU3162895A (fr) |
| CA (1) | CA2195867A1 (fr) |
| DE (1) | DE4426315C1 (fr) |
| WO (1) | WO1996003094A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6942873B2 (en) | 2000-09-25 | 2005-09-13 | The Board Of Trustees Of The University Of Illinois | Microfabrication of membranes containing projections and grooves for growing cells |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19648876C2 (de) * | 1996-11-16 | 1999-10-07 | Will Minuth | Verfahren zum Herstellen eines natürlichen Implantats |
| US6420622B1 (en) | 1997-08-01 | 2002-07-16 | 3M Innovative Properties Company | Medical article having fluid control film |
| CH692583A5 (de) * | 1998-03-03 | 2002-08-15 | Weidmann H Ag | Kulturgefäss. |
| US6143293A (en) * | 1998-03-26 | 2000-11-07 | Carnegie Mellon | Assembled scaffolds for three dimensional cell culturing and tissue generation |
| DE19940977A1 (de) * | 1999-08-28 | 2001-03-01 | Lutz Claes | Folie aus resorbierbarem Polymermaterial und Verfahren zur Herstellung einer solchen Folie |
| DE10014557A1 (de) * | 2000-03-23 | 2001-10-04 | Lohmann Therapie Syst Lts | Wundauflage mit verminderter Verwachsungstendenz |
| ITRM20040379A1 (it) * | 2004-07-27 | 2004-10-27 | Uni Degli Studi Di Roma La Sapienza | Supporto tridimensionale per la coltura di cellule, metodo di coltura facente uso di tale supporto e cellule con caratteristiche staminali ottenute attraverso tale metodo. |
| DE102012011422A1 (de) | 2012-06-08 | 2013-12-12 | Gottlieb Binder Gmbh & Co. Kg | Medizinprodukt zur Versorgung eines Individuums |
| US11963684B2 (en) * | 2020-03-18 | 2024-04-23 | Bvw Holding Ag | Microstructured hemostat |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3457919A (en) * | 1966-06-22 | 1969-07-29 | Smith & Nephew | Adhesive surgical and other tapes,plasters,bandages,dressings,and the like |
| US4175557A (en) * | 1975-11-24 | 1979-11-27 | International Paper Company | Polymeric sheets |
| US5182111A (en) * | 1987-11-17 | 1993-01-26 | Boston University Research Foundation | In vivo delivery of active factors by co-cultured cell implants |
| NL8801741A (nl) * | 1988-07-08 | 1990-02-01 | Utermoehlen Nv | Kunsthuid. |
| DE3923279A1 (de) * | 1989-07-14 | 1990-01-18 | Will W Prof Dr Minuth | Minusheets ist ein neues produkt, um zellen in beliebigen behaeltnissen in hochdifferenzierter form auf einer moeglichst natuerlichen unterlage zu kultivieren |
| US5188124A (en) * | 1989-07-19 | 1993-02-23 | Johnson & Johnson Consumer Products, Inc. | Low friction film dressing |
| GB9004911D0 (en) * | 1990-03-05 | 1990-05-02 | Smith & Nephew | Cell culture products |
| DE9003033U1 (de) * | 1990-03-13 | 1991-04-11 | Beiersdorf Ag, 20253 Hamburg | Trägermaterial für medizinische Zwecke |
| IT1248934B (it) * | 1990-06-01 | 1995-02-11 | Fidia Spa | Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle |
| DE69108136T2 (de) * | 1990-08-03 | 1995-11-02 | Terumo Corp | Wundabdeckmaterial. |
| US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
| DE4132379A1 (de) * | 1991-09-28 | 1993-04-08 | Kernforschungsz Karlsruhe | Substrat fuer zellkulturen und kultur von zellen oder zellaggregaten |
-
1994
- 1994-07-25 DE DE19944426315 patent/DE4426315C1/de not_active Expired - Fee Related
-
1995
- 1995-07-20 AU AU31628/95A patent/AU3162895A/en not_active Abandoned
- 1995-07-20 EP EP95927681A patent/EP0772425A1/fr not_active Ceased
- 1995-07-20 CA CA 2195867 patent/CA2195867A1/fr not_active Abandoned
- 1995-07-20 WO PCT/EP1995/002869 patent/WO1996003094A1/fr not_active Ceased
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6942873B2 (en) | 2000-09-25 | 2005-09-13 | The Board Of Trustees Of The University Of Illinois | Microfabrication of membranes containing projections and grooves for growing cells |
| US7695967B1 (en) | 2000-09-25 | 2010-04-13 | The Board Of Trustees Of The University Of Illinois | Method of growing stem cells on a membrane containing projections and grooves |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3162895A (en) | 1996-02-22 |
| EP0772425A1 (fr) | 1997-05-14 |
| DE4426315C1 (de) | 1996-03-21 |
| WO1996003094A1 (fr) | 1996-02-08 |
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