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CA2195663A1 - Dihydrobenzofuranes - Google Patents

Dihydrobenzofuranes

Info

Publication number
CA2195663A1
CA2195663A1 CA002195663A CA2195663A CA2195663A1 CA 2195663 A1 CA2195663 A1 CA 2195663A1 CA 002195663 A CA002195663 A CA 002195663A CA 2195663 A CA2195663 A CA 2195663A CA 2195663 A1 CA2195663 A1 CA 2195663A1
Authority
CA
Canada
Prior art keywords
dihydrobenzofuranes
compounds
inhibitors
novel
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002195663A
Other languages
French (fr)
Other versions
CA2195663C (en
Inventor
Wolf-Rudiger Ulrich
Ulrich Thibaut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/EP1995/002841 external-priority patent/WO1996003399A1/en
Publication of CA2195663A1 publication Critical patent/CA2195663A1/en
Application granted granted Critical
Publication of CA2195663C publication Critical patent/CA2195663C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention concerns compounds of formula (I), in which R1, R2, R3 and R4 have the meanings given in the description.
These compounds are novel, effective PDE--inhibitors.
CA002195663A 1994-07-22 1995-07-19 Dihydrobenzofuranes Expired - Fee Related CA2195663C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH2323/94-3 1994-07-22
CH232394 1994-07-22
PCT/EP1995/002841 WO1996003399A1 (en) 1994-07-22 1995-07-19 Dihydrobenzofuranes

Publications (2)

Publication Number Publication Date
CA2195663A1 true CA2195663A1 (en) 1996-02-08
CA2195663C CA2195663C (en) 2006-10-24

Family

ID=37309453

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002195663A Expired - Fee Related CA2195663C (en) 1994-07-22 1995-07-19 Dihydrobenzofuranes

Country Status (1)

Country Link
CA (1) CA2195663C (en)

Also Published As

Publication number Publication date
CA2195663C (en) 2006-10-24

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed