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CA2195283A1 - Process for manufacturing iron dextran using ultrafiltration - Google Patents

Process for manufacturing iron dextran using ultrafiltration

Info

Publication number
CA2195283A1
CA2195283A1 CA002195283A CA2195283A CA2195283A1 CA 2195283 A1 CA2195283 A1 CA 2195283A1 CA 002195283 A CA002195283 A CA 002195283A CA 2195283 A CA2195283 A CA 2195283A CA 2195283 A1 CA2195283 A1 CA 2195283A1
Authority
CA
Canada
Prior art keywords
ultrafiltration
iron dextran
manufacturing iron
dextran
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002195283A
Other languages
French (fr)
Other versions
CA2195283C (en
Inventor
Thomas C. Usher
Natu Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002195283A priority Critical patent/CA2195283C/en
Publication of CA2195283A1 publication Critical patent/CA2195283A1/en
Application granted granted Critical
Publication of CA2195283C publication Critical patent/CA2195283C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

A process for manufacturing Iron Dextran comprising, forming a direct complex of dextran with ferric chloride, and using an ultrafiltration membrane having a molecular weight cut off between 5,000 to 50,000 to purify the product.
CA002195283A 1997-01-16 1997-01-16 Process for manufacturing iron dextran using ultrafiltration Expired - Fee Related CA2195283C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002195283A CA2195283C (en) 1997-01-16 1997-01-16 Process for manufacturing iron dextran using ultrafiltration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002195283A CA2195283C (en) 1997-01-16 1997-01-16 Process for manufacturing iron dextran using ultrafiltration

Publications (2)

Publication Number Publication Date
CA2195283A1 true CA2195283A1 (en) 1998-07-16
CA2195283C CA2195283C (en) 2008-07-22

Family

ID=4159676

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002195283A Expired - Fee Related CA2195283C (en) 1997-01-16 1997-01-16 Process for manufacturing iron dextran using ultrafiltration

Country Status (1)

Country Link
CA (1) CA2195283C (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1858930B1 (en) 2005-03-15 2011-07-20 Biofer S.p.A. Process for the preparation of trivalent iron complexes with mono-, di- and polysaccharide sugars
CN103224571A (en) * 2013-04-08 2013-07-31 江苏久吾高科技股份有限公司 Method for purifying polysaccharide iron complex based on ultrafiltration membrane method
CN106526050A (en) * 2015-09-15 2017-03-22 河北远征药业有限公司 Method for determining content of phenol in iron dextran injection liquid
US11123321B2 (en) 2002-10-23 2021-09-21 Vifor (International) Ag Aqueous iron carbohydrate complexes, their production and medicaments containing them
CN113480678A (en) * 2021-08-06 2021-10-08 江西华太药业有限公司 Iron dextran synthesizing method and its dispersing tablet
US11344568B2 (en) 2006-01-06 2022-05-31 American Regent, Inc. Methods and compositions for administration of iron

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104829745B (en) * 2015-04-29 2017-03-08 江西华太药业有限公司 A kind of iron-dextrin and preparation method thereof
CN110183548B (en) * 2019-06-28 2021-05-18 瑞普（天津）生物药业有限公司 A kind of preparation method and application of low molecular weight glucan iron

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11123321B2 (en) 2002-10-23 2021-09-21 Vifor (International) Ag Aqueous iron carbohydrate complexes, their production and medicaments containing them
US11291645B2 (en) 2002-10-23 2022-04-05 Vifor (International) Ag Aqueous iron carbohydrate complexes, their production and medicaments containing them
EP1858930B1 (en) 2005-03-15 2011-07-20 Biofer S.p.A. Process for the preparation of trivalent iron complexes with mono-, di- and polysaccharide sugars
US11406656B2 (en) 2006-01-06 2022-08-09 American Regent, Inc. Methods and compositions for administration of iron
US12329772B2 (en) 2006-01-06 2025-06-17 American Regent, Inc. Methods and compositions for administration of iron
US11478502B2 (en) 2006-01-06 2022-10-25 American Regent, Inc. Methods and compositions for administration of iron
US11433091B2 (en) 2006-01-06 2022-09-06 American Regent, Inc. Methods and compositions for administration of iron
US11344568B2 (en) 2006-01-06 2022-05-31 American Regent, Inc. Methods and compositions for administration of iron
US11364260B2 (en) 2006-01-06 2022-06-21 American Regent, Inc. Methods and compositions for administration of iron
CN103224571A (en) * 2013-04-08 2013-07-31 江苏久吾高科技股份有限公司 Method for purifying polysaccharide iron complex based on ultrafiltration membrane method
CN103224571B (en) * 2013-04-08 2015-04-29 江苏久吾高科技股份有限公司 Method for purifying polysaccharide iron complex based on ultrafiltration membrane method
CN106526050A (en) * 2015-09-15 2017-03-22 河北远征药业有限公司 Method for determining content of phenol in iron dextran injection liquid
CN106526050B (en) * 2015-09-15 2018-06-19 河北远征药业有限公司 The content assaying method of phenol in a kind of iron dextran injection
CN113480678B (en) * 2021-08-06 2022-03-25 江西华太药业有限公司 Iron dextran synthesizing method and its dispersing tablet
CN113480678A (en) * 2021-08-06 2021-10-08 江西华太药业有限公司 Iron dextran synthesizing method and its dispersing tablet

Also Published As

Publication number Publication date
CA2195283C (en) 2008-07-22

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Legal Events

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MKLA Lapsed

Effective date: 20150116