CA2163450A1 - Facteurs embryotoxiques - Google Patents
Facteurs embryotoxiquesInfo
- Publication number
- CA2163450A1 CA2163450A1 CA002163450A CA2163450A CA2163450A1 CA 2163450 A1 CA2163450 A1 CA 2163450A1 CA 002163450 A CA002163450 A CA 002163450A CA 2163450 A CA2163450 A CA 2163450A CA 2163450 A1 CA2163450 A1 CA 2163450A1
- Authority
- CA
- Canada
- Prior art keywords
- embryotoxic
- factor
- concentration
- sample
- reproductive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/52—Sperm; Prostate; Seminal fluid; Leydig cells of testes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physiology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
Abstract
L'invention concerne des procédés et des compositions de diagnostic et de traitement d'anomalies reproductives immunologiques chez le mammifère. Lesdits procédés consistent à déterminer la présence d'une concentration élevée d'un facteur embryotoxique extracellulaire dans un échantillon. Ledit échantillon contient des leucocytes ou des produits de sécrétion de leucocytes. L'invention porte également sur le matériel permettant de déterminer la concentration desdits facteurs embryotoxiques.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6590393A | 1993-05-21 | 1993-05-21 | |
| US08/065,903 | 1993-05-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2163450A1 true CA2163450A1 (fr) | 1994-12-08 |
Family
ID=22065922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002163450A Abandoned CA2163450A1 (fr) | 1993-05-21 | 1994-05-20 | Facteurs embryotoxiques |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0700523A1 (fr) |
| AU (1) | AU6954494A (fr) |
| CA (1) | CA2163450A1 (fr) |
| WO (1) | WO1994028425A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002022877A2 (fr) * | 2000-09-12 | 2002-03-21 | The Brigham And Women's Hospital, Inc. | Variants de gene il-1 chaine beta et de gene cd46 pour le diagnostic de perte de gestation recurrente non expliquee |
| EP1448178A1 (fr) * | 2001-11-30 | 2004-08-25 | Solvay Pharmaceuticals GmbH | Prevention de fausse couche faisant appel a des composes gestagenes non endogenes d'immunomodulation |
| US20140051598A1 (en) | 2011-03-17 | 2014-02-20 | Cedars-Sinai Medical Center | Diagnostic biomarker to predict women at risk for preterm delivery |
| ITMI20130916A1 (it) * | 2013-06-04 | 2014-12-05 | Gexnano S R L | Metodo di rilevazione di sostanze chimiche in campioni di materiale prelevabili da un soggetto, in particolare di rilevazione di fattori embriotossici |
| US20160130553A1 (en) | 2014-05-15 | 2016-05-12 | Kellbenx Incorporated | PREPARATION OF FETAL NUCLEATED RED BLOOD CELLS (NRBCs) FOR DIAGNOSTIC TESTING |
| US12202890B1 (en) | 2014-11-07 | 2025-01-21 | Kellbenx Incorporated | Antibodies for detection and enrichment of fetal cells and their use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8801383A1 (es) * | 1985-06-27 | 1988-01-01 | Biogen Nv | Un procedimiento para purificar uromodulina a partir de orina cruda |
| EP0400083A1 (fr) * | 1988-03-18 | 1990-12-05 | Institut National De La Recherche Agronomique (Inra) | Isoformes de la trophoblastine, nouveaux interferons constitues par lesdites isoformes, leurs procedes d'obtention et leurs applications |
| US4997646A (en) * | 1989-02-23 | 1991-03-05 | University Of Florida Research Foundation, Inc. | Use of interferons of the alpha family to enhance fertility in mammals |
| CA2121680C (fr) * | 1991-11-04 | 2005-03-22 | Andrew E. Senyei | Methode de depistage de femmes a risque eleve d'accouchement premature |
| JPH05209882A (ja) * | 1992-01-31 | 1993-08-20 | Tosoh Corp | 流早産の診断方法 |
-
1994
- 1994-05-20 AU AU69544/94A patent/AU6954494A/en not_active Abandoned
- 1994-05-20 CA CA002163450A patent/CA2163450A1/fr not_active Abandoned
- 1994-05-20 EP EP94918062A patent/EP0700523A1/fr not_active Withdrawn
- 1994-05-20 WO PCT/US1994/005692 patent/WO1994028425A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994028425A1 (fr) | 1994-12-08 |
| AU6954494A (en) | 1994-12-20 |
| EP0700523A1 (fr) | 1996-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Yamada et al. | Cell-mediated immunity to trophoblast antigens in women with recurrent spontaneous abortion | |
| Margalioth et al. | Correlation between the zona-free hamster egg sperm penetration assay and human in vitro fertilization | |
| Katz et al. | Recurrent miscarriage | |
| EP1927362A2 (fr) | Intégrine alpha/bêta 3 en tant que prédicateur d'endométrioses | |
| Athanassakis et al. | Placental tissue from human miscarriages expresses Class II HLA‐DR antigens | |
| US7723289B2 (en) | PIF tetrapeptides | |
| Hornung et al. | Histocompatibility leukocyte antigen-G is not expressed by endometriosis or endometrial tissue | |
| CA2163450A1 (fr) | Facteurs embryotoxiques | |
| US20120107318A9 (en) | Methods of administering pif agonist peptides and uses thereof | |
| Oikonomou et al. | Human leukocyte antigen alleles compatibility and immunophenotypic profile associations in infertile couples | |
| AU2004284097A1 (en) | PIF peptides biologic activities, site of action, and the antibody to detect PIF | |
| McShane et al. | Cellular immunity to sperm in infertile women | |
| Hjort et al. | Anti-sperm antibodies and immune subfertility | |
| Radojčić et al. | Anticardiolipin antibodies in women with unexplained infertility | |
| Ohashi et al. | Evaluation of acrosomal status using MH61-beads test and its clinical application | |
| Tedesco et al. | Prevalence and biological effects of anti‐trophoblast and anti‐endothelial cell antibodies in patients with recurrent spontaneous abortions | |
| Chandra et al. | Post-translational modifications in glycosylation status during epididymal passage and significance in fertility of a 33 kDa glycoprotein (MEF3) of rhesus monkey (Macaca mulatta) | |
| MacLaren et al. | Maternal serum reactivity to species-specific antigens in sheep-goat interspecific pregnancy | |
| ALLEN et al. | Immunosuppression in the mouse by porcine uterine secretory protein | |
| US11422138B2 (en) | Detection and treatment of pregnancy complications comprising determining sialyl Lewis antigens and administering hCG | |
| Raut et al. | Lymphocyte immunization therapy (LIT) in reproductive failures | |
| Ekroth | The relationship between gamete compatibility and immune system | |
| Zhao et al. | Maternal and Fetal CD4+ CD25+ CD127low/-Regulatory T Cells in Pregnancies with Gestational Diabetes, Preeclampsia, and Premature Rupture of Membranes | |
| Kamada et al. | Sperm-zona pellucida interaction and immunological infertility | |
| Gulati | A Springboard Fellowship: Investigating the T cell repertoire in malplacentation disorders and developing a novel classification system for assigning cause of death in twin pregnancies |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |