[go: up one dir, main page]

CA2163125A1 - Immunoglobulines concues par voie genetique - Google Patents

Immunoglobulines concues par voie genetique

Info

Publication number
CA2163125A1
CA2163125A1 CA002163125A CA2163125A CA2163125A1 CA 2163125 A1 CA2163125 A1 CA 2163125A1 CA 002163125 A CA002163125 A CA 002163125A CA 2163125 A CA2163125 A CA 2163125A CA 2163125 A1 CA2163125 A1 CA 2163125A1
Authority
CA
Canada
Prior art keywords
immunoglobulin
cells
peptide
molecule
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002163125A
Other languages
English (en)
Inventor
Maurizio Zanetti
Rosario Billetta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2163125A1 publication Critical patent/CA2163125A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205Plasmodium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne l'introduction d'épitopes oligopeptidiques de la nucléoprotéine du virus de la grippe de manière à provoquer leur expression dans le repli tridimensionnel d'une molécule d'immunoglobuline (Ig) et à produire des molécules utilisées pour induire une immunité antivirale spécifique biologiquement active.
CA002163125A 1993-05-28 1994-05-25 Immunoglobulines concues par voie genetique Abandoned CA2163125A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6889593A 1993-05-28 1993-05-28
US08/068,895 1993-05-28

Publications (1)

Publication Number Publication Date
CA2163125A1 true CA2163125A1 (fr) 1994-12-08

Family

ID=22085391

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002163125A Abandoned CA2163125A1 (fr) 1993-05-28 1994-05-25 Immunoglobulines concues par voie genetique

Country Status (4)

Country Link
EP (1) EP0701573A1 (fr)
JP (1) JPH08510912A (fr)
CA (1) CA2163125A1 (fr)
WO (1) WO1994028026A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5969109A (en) * 1990-02-28 1999-10-19 Bona; Constantin Chimeric antibodies comprising antigen binding sites and B and T cell epitopes
EP2258712A3 (fr) * 2002-03-15 2011-05-04 Multicell Immunotherapeutics, Inc. Compositions et procédés permettant d'initier ou d'ameliorer les réponses des cellules T limitées par le complexe majeur d 'histocompatibilité de classe I ou II et un anticorps au moyen de motifs d'ARN non codants immunomodulateurs

Also Published As

Publication number Publication date
WO1994028026A1 (fr) 1994-12-08
EP0701573A1 (fr) 1996-03-20
JPH08510912A (ja) 1996-11-19

Similar Documents

Publication Publication Date Title
US5508386A (en) Antigenized antibodies and genes
Zaghouani et al. Cells expressing an H chain Ig gene carrying a viral T cell epitope are lysed by specific cytolytic T cells.
JP4216473B2 (ja) Hiv感染および免疫疾患の予防および治療のペプチド組成物
EP0833929B1 (fr) Anticorps chimeriques pour l'acheminement d'antigenes jusqu'a des cellules selectionnees du systeme immunitaire
WO1996019584A1 (fr) Anticorps chimeres comprenant des sites de liaison a l'antigene et des epitopes des lymphocytes b et t
WO1996019584A9 (fr) Anticorps chimeres comprenant des sites de liaison a l'antigene et des epitopes des lymphocytes b et t
NO324047B1 (no) Hoyaffinitetshumane monoklonale antistoff spesifikke for RSV F-protein samt anvendelse derav
AU2003214044B2 (en) Anti-idiotypic antibody inducing HIV-1 neutralizing antibodies
Billetta et al. Major histocompatibility complex class I‐restricted presentation of influenza virus nucleoprotein peptide by B lymphoma cells harboring an antibody gene antigenized with the virus peptide
US6291208B1 (en) Chimeric antibodies for delivery of antigens to selected cells of the immune system
CA2163125A1 (fr) Immunoglobulines concues par voie genetique
AU672580B2 (en) Chimeric immunoglobulin molecules
US20020025315A1 (en) Chimeric antibodies for delivery of antigens to selected cells of the immune system
Kuzu et al. Priming of cytotoxic T lymphocytes at various stages of ontogeny with transfectoma cells expressing a chimeric Ig heavy chain gene bearing an influenza virus nucleoprotein peptide
WO1989010939A1 (fr) Immunogenes et peptides biologiquement actifs derives de sequences partagees d'antigenes et d'anticorps anti-idiotypiques ou d'anticorps specifiques contre des recepteurs cellulaires des antigenes
Krystal Cells expressing an H chain Ig gene carrying a viral T cell epitope are lysed by specific cytolytic T cells
HK1036805B (en) Antigenic complex comprising immunostimulatory peptide, cd4, and chemokine receptor domain for hiv treatment and immune disorders

Legal Events

Date Code Title Description
FZDE Discontinued