CA2155861A1 - Effervescent pesticide tablet with metal perborate - Google Patents

Abstract

An effervescent tablet formulation about 0.1 % to 75 % of a water-soluble pesticide and about 25 % to 99.9 % of an anhydrous metal perborate salt characterized by rapid breakup in cold water.

Description

, 215$861 TITLE
EFFERVESCENT PESTICIDE TABLET WITH METAL PERBORATE
WO 90/00007 discloses pesticidal tablets comprising an acid and a base which react upon contact with water to produce the ~ff~.vc3c~ reaction that 5 causes the pestici(l~ to rapidly lis~erse. The present tablets differ from those of WO 90/00007 in several iullpo~ aspects inrlu(ling the fact that it is the reaction of al-hydlous perborate salts with water that produces the ef~lvesccnl re~ction SUMMARY OF THE INVENTION
This invention conce~lls a tablet formulation colll~lisillg, by total weight of the formulation, about 0.1% to 75% of a water-soluble pesticide which is solid at room lelllp~turt, and 25% to 99.9% of an al~hydr~us metal ~cll,ol~le salt.
By "tablet formulation" is meant the tablet made from the composition described herein, as well as the colllposilion formulated in acconl~lcc with this disclosure but not in taUet form. By "anlly~ous metal perborate salt" is meant asodium, lithium, or pol~ salt having a water content less than about 2% by weight as det~rnin~ by coulometric meas~ .nent.
Plcfe.l~d ranges of the composition are 10% to 70%, and more p~fcll~d 30% to 60%, of the pesticide, and 30% to 90%, and more plcfell~d 40% to 70%, of the anhydrous metal perborate.
Conlc.llplated water-soluble, solid pesticides include those sele~lc;l from the following classes, in~lu(ling mi~tures tl.cn,of. herbicides, fimgici(1çs, b~çterici~le~, and insecticides. Plcfe~lcd pe~l ;cide~ are those having a melting point of at least about 75C and solubility in pH 7 water at 20C of at least about 2% by weight.
FY~mples of snit~ble water-soluble pesticides in~lucle: insecticides such as methomyl and o~amyl; f~ln~isides such as dodine salts, phosell,yl-Al, k~s~ mycin, and valid~y~ ; bactericides such as ~llcptoll.ycin and tribasic copper sulfate; and herbicides such as sulfonylurea salts, acifluorfen salts, ammonium ~nlf~ te, amitrole, bromo~cynil salts, cacodylic acid salts, clopyralidsalts, calcium salt of methylarsonic acid, dalapon salts, dazomet, dicamba salts, 30 difenzoquat methyl sulfate, diquat, 2-methyl-4,6-diilro~,.lol salts, disodium salt of methylarsonic acid, endothall, fenac, salt of fenuron and trichloroacetic acid, flulo~y~yl salts, fomesafen, fosamine ammonium, glyphosate salts, haloxyfop salts, h~flurate, im~7~-lnin salts, imazethapyr salts, io~ynil sodium salt, monoammonium salt of methylarsonic acid, (4-chloro-2-mell-ylphe.lo~y)acetic 35 acid salts, MCPP salts, mecoplup salts, mefl~ salts, metam sodium, monuron 2l5586`
WO 94/17660 ~ PCT/US94/00068 salt, monosodium salt of methylarsonic acid, naptalam, p~raq~l~t salts, picloramsalts, quinchlorac salts, sodium 2-chloro-6-[(4,6-dimetho~y-2-pyrimidinyl)thio]l,enzoale, trichloro&cclic acid salts, triclopyr salts, (2,4-dichlolo~he.lo~y)acetic acid salts, and 4-(2,4-dichloropheno~y)l~ulal~oic acid.
S Contemplated sul~n~lurca salts have the formula:

2 G;~ M

w~ l J is selected from the group R2~ ~ ~1CH3-- SJ~

S~ 5 '1~ ~ R7 J-4 ~ ~ J-6 `R6 R N R9)lN~N

~15586 1~.
Wo 94/17660 PCT/US94/00068 R~ R10 ~ R9 R5 6 R8 R8 ~ R8 J-10 J-ll J-12 ~7 I R6 R I

R is selected from the group H and CH3;
Rl is selected from the group F, Cl, Br, N02, Cl-C4 alkyl, Cl-C4 haloaLkyl, C3-C4 cycloaLyl, C2-C4 haloalkenyl, Cl-C4 alkoxy, Cl-C4 haloaLo~y, C2-C4 alko~yaLo~y, C02R12, C(o)NRl3Rl4, So2NRl5Rl6, S(o)nR17, C(O)Rl8, CH2CN and L;
R2 is selected from the group H, F, Cl, Br, CN, CH3, OCH3, SCH3, CF3 and OCF2H;
R3 is selected from the group Cl, NO2, CO2CH3, CO2CH2CH3, SO2N(CH3)2, SO2CH3, So2cH2cH3~ OCH3, and OCH2CH3 R4 is sele~ l~,d from the group Cl-C3 aLyl, Cl-C2 haloalkyl, Cl-C2 alko~cy, C2-C4 h~loAlk~nyl, F, Cl, Br, NO2, CO2R12, C(o)NR13R14, So2NR15R16, S(o)nR17, C(O)R18 and L;
R5 is selected from the group H, F, Cl, Br and CH3;
R6 is selected from the group Cl-C3 aLkyl, Cl-C2 alkoxy, C2-C4 haloalkenyl, F, Cl, Br, C02R12, C(o)NRl3R14, So2NRl5Rl6 S(o)nRl7, C(O)R18 and L;
R7 is selected from the group H, F, Cl, CH3 and CF3;

R8 is selected from the group H, Cl-C3 aLkyl and pyridyl;
R9 is selected from the group Cl-C3 alkyl, Cl-C2 alko~y, F, Cl, Br, N02, C02R12, So2NR15R16, S(o)nRl7~ OCF2H, C(O)R18, C2-C4 haloalkenyl and L;

WO 94/17660 ~,~55Qo PCTIU594/00068 R10 is selected from the group H, Cl, F, Br, Cl-C3 aL~yl and Cl-C2 alko~cy;
Rll is selected from the group H, Cl-C3 alkyl, Cl-C2 aLko~cy, C2-C4 haloalkenyl, F, Cl, Br, C02R12, C(o)NR13Rl4, So2NRl5Rl6 S(o)nR17, C(O)R18 and L;
R12 is selected from the group allyl and pr~dr~,yl and Cl-C3 optionally sub~ uled by at least one member indepPn~lPntly selected from halogen, Cl-C2 alko~cy and CN;
R13 is sclccled from the group H, Cl-C3 a,ll~yl and Cl-C2 alko~cy;
R14 is Cl-C2 aL~cyl;
R15 is selecled from the group H, Cl-C3 alkyl, Cl-C2 alko~y, allyl and cyclopropyl;
R16 is selected from the group H and Cl-C3 alkyl;
R17 is selected from the group Cl-C3 aL~yl, Cl-C3 haloalkyl, allyl and yl;
R18 is selected from the group Cl-C4 alkyl, Cl-C4 haloalkyl and C3-Cs cycloalkyl optionally sub~ ul~d by halogen;
nisO, 1 or2;
M is a cation;
L is Rj N N
N~N

Rj is selected from the group H and Cl-C3 alkyl;
W is selected from the group O and S;
X is selected from the group H, Cl-C4 alkyl, Cl-C4 alko~y, Cl-C4 haloalko~cy, Cl-C4 haloalkyl, Cl-C4 haloalkylthio, Cl-C4 alkylthio, halogen, C2-C5 alko~cyalkyl, C2-Cs alko~cyalko~cy, amino, Cl-C3 alkylamino and di(Cl-C3 aL~cyl)amino;
Y is selected from the group H, Cl-C4 aLkyl, Cl-C4 alko~y, Cl-C4 haloaL~co~y, Cl-C4 aLkylthio, Cl-C4 haloalkylthio, C2-C5 alkoxyalkyl, C2-C5 aLko~yaLkoxy, amino, Cl-C3 aLkylamino, di(Cl-C3 alkyl)amino, C3-C4 alkenyloxy, C3-C4 aLkynyloxy, C2-C5 alkylthioaLkyl, C2-C5 aLkylsulfinylaLkyl, C2-Cs aLkylsulfonylalkyl, wO 94/17660 2 ~ S S 8 6 I PCT/US94/00068 Cl-C4 haloaLkyl, C2-C4 aLkynyl, C3-Cs cycloalkyl, azido and cyano;
and Z is selected from the group CH and N;
provided that i) when one or both of X and Y is Cl haloalko~cy, then Z is 5 CH; and ii) when X is halogen, then Z is CH and Y is OCH3, OCH2CH3, N(OCH3)CH3, NHCH3, N(CH3)2 or OCF2H.
Pl~rcll~ d active in~ ,d;~nl~, are salts of the following s-wÇonylw. as,.
chlorsulfuron; sulfometuron; chlorimuron ethyl; metsulfuron methyl; methyl 2-[[[[(4~6-d~lelhw~y-2-pyrimi~linyl)-amino]c~lJollyl]-amino]sulfonyl]-6-10 (trifluolulllelllyl)-3-pyri~ ec~'uuAylate; ethametsulfuron methyl; triasulfuron;
ethyl 5-[[[[(4~6-dimethoxy-2-pyrimitlinyl)amino]carbonyl]-amino]sulfonyl]
methyl-lH-pyrazole4-ca.l,u~late; N-[[(4,6-dimetho~cy-2-pyrimidinylamino]ca,~,ullyl]-3-(ethyls-wfonyl)-2-pyrirlin~s~1fonamide;
tl.;r~ ..lfuron; llib~ .lwull methyl; bens-wfuron methyl; nicosulfuron; methyl 2-15 [[[[[4~6-bis(difluorometho~y)-2-pyrimitlinyl]amino]ca~bu~ l]amino]sulfonyl]-benzoate; methyl 2-[[[[[4-dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl]amino]-cd~ yl]amino]sulfonyl]-3-methyl'L~ 74;~; and N-[[(4,6-~1imetho~y-2-pyrimidinyl)amino]calbollyl]-l-methyl-4-(2-methyl-2H-tetra yl)-lH-yyl~ol~-s-sulforl~mi~
Plcrcll~d salts are the sodium, yOlAP~ , c~ inm~ m~g.~ ~;.. , ammonium and alkylammonium salts of a s-wÇûllylw-,a. Most yl~,f .l~d sulÇull.~lw~a salts are the sodium and calcium salts of hi~.lwun methyl, the pol~s;~.. salt of !I.;r~ --lfilron methyl, the ammonium salt of chlorsulfuron and the ~OIA~S;~ salt of metsulfuron methyl.
DETAILED DESCRIPTION OF THE INVENTION
The most common method for applying pestici(les is as aqueous solutions or dis~ ions which are sprayed onto the field or crop using ground or aerial spray rigs. A tablet cont~ining the pestic~ l COl.lpOlle.-l iS an crr~clive form for introducing the pesticide into the water in the spray tank. It is ~ub~ lly i llpossible to obtain rapid break-up of a tablet willluul the use of errc. v~scence.
Rapid break-up in water is desirable for the conve.~nce of the ~lu~cl~ who require quick lwll~uulld times for the lulep~lion of the spray solutions and dispersions.
Known cr~vcsc~ pesti~ tablets co.. ~ e a water-insoluble pesticide, 35 an organic acid and a co~lJon~lc or bic~l,ondle base. The acid and base react in 2l5s86~\l WO 94/17660 PCT/US94/00068 ~

an aqueous ellvilu~ ent to produce carbon dio-Aide gas which aids in the break-up of the tablet and dispersion of the pesticide. However, the rate of the acid-base effervescent reaction slows .~ignific~ntly when the tablet co~ uliSeS a water-soluble pesticide. A soft "hydrogel" is believed to form around the tablet to S inhibit water from CO.~ g the tablet and f~ilit~ting the ~cl ;ol--Disintegration rates are ll,~cfolc too slow for pr~ctic~l appli~ ~tion.~. In cases where the pe~icide is a water-soluble metal salt, the acid in the tablet may react with the pestici(le to give the water-insoluble acid form.
No hydrogel formation or precipitate is obs~. ved in the reaction of the 10 tablets of the present invention with water. Effervesce~-ce begins i~ uusly and complete disi~ gl~lion occurs in less than 10 mimltes~ most often in less than 5 minnteS using even the cold water drawn from wells in the early spring. A clear aqueous solution forms with the pesticide homogeneously dissolved therein.
Inert ingredients up to about 74.9% of the total weight of the colllposilion lS can be employed. Such inert ingredients are colll~olle.l~, comrlemPnt~ry to the pestici-l , which are known in the tablet art to illlprovc tablet ~ le~ ralion rate, di~el~ibility, stability during storage, and the like. E-Aamples of optional colllponenl~ include a m~ng~npse~ copper or iron salt catalyst; a di~c~ ll, a disintegrant; an anionic or noniollic wetting agent; a flow aid, and a desiccant.
20 The amounts and types of such ill~;lcdienls will be readily detçrmin ah le by one skilled in the ~ lc~ e art given the disclosure herein.
The crr~. v~,scenl reaction is due to the ~Ihy~`~us metal perborate reacting with the water to liberate oxygen. Any such colllpoul~d which is collll,~tiUe with the pesticide and liberates o-Aygen upon hydration is ~u;lu~le for the tablets of the 25 present invention. The ~>rtrc.l~d colll,uoulld is ~lly~`ous sodium lu~ lbolale (also known as sodium l,~,uAylll~tabol. tc, NaB03).
Metal ~.l,or~lc is commonly available commercially as the monohydrate.
The monohydrate must be coll~ d to its a~hydl~ous state in order for the effervescent reaction to occur. The conv~ ion of the metal pell,olale 30 monohy~llale to its anhy~ us form can be accol..pli~hPd by oven-drying the granules at 135C for 24 hours in a vacuum oven with a llillugcll bleed to obtain a uiC of 1.33 A 103 Pascal. The sodium ~lluulale is spread in a layer less than 2 cm in thickness to facilitate drying. As a result of the drying, sodium pell,ol~le has been found to change color from white to yellow.

215586:~

The success of the drying procedure can be tested by bl~n-ling the dried sample to a homogenous mi~ture, and then dlu~i~g a small amount of the mi~ture into a beaker of water. If all the m~tçris~1 reacts (i.e., er~l~esces) on the surface of the water, and no residue (i.e., monohr&d~e) falls to the bottom of the 5 beaker, then the al~hrd~,us state was achieved.
If small amounts of the monollydl~le pe.l,o,dte are not col~ t~d to the anhydrous form during drying, a metal salt can be added in catalytic amounts to dccollll)ose the Illonohrd-~le to produce o~ygen and other products.
Monohr(l,~te which is not de~oy. d by a catalyst will not e~f sce when 10 cûnla~ d with water, but it does &ssolve within the time .~f ce~ y for disintegration of the tablet (i.e., less than 10 min~)tes). Pl~fe.l~d catalyst salts include m~n~nPse, copper or iron metal o~ides or carbonates. Most pl`tr~ d is iron (II) o~ide.
Di*,c,~.~ds can be added to aid the initial dis~.ion of the particles of the 15 active ingredient which are liberated during ~ eg~t;on of the tablet. Suitable di~. l~.~lts include sûdium, llOl~-.~.iulll and c~lcillm salts of l~al~h~ 1c.~r sulfonic acid form~ldfçhyde Co~ f..~.C~'~t~,S, lithinm, sodium, pol~ ...., c~lcillm, and ammonium salts of lignoslll rolldl~s such as Polyfon H0 and Lignosol TSF0;
sodium, pot~!s;.. and ammonium salts of polyacrylates and c~u'l,o~ylates, e.g., 20 Tamol 731 SD~9; sodium salts of maleic anhydride-isobulylene co~olyllle. ., and water soluble nonionic polyllle.~. such as polyvinyl~yllùli-ionP7 polyethylene o~ides and cçllnlose d~;~/ali~s. ~l~,f~ d di~ .alllS indude the sodium, S;-~--, ammonium and c~ lm salts of ~ lPnç sulfonic acid fonn~ Phyde c~ es, with the ammonium salts, ~ e~-;rir~lly Lomar PWA~9, 25 more pl~f~l~d.
Disintegrants façilit~te pe.l~ ~lion of the water into the interior of the tablet through a wiclcing or swelling action. Water-insoluble cross-linked polyvinylpolypyrrolidone is apleÇe.l~d~ ;..t~
A wetting agent can be used to control the size of the oxygen bubbles 30 fonned during the acid-base reaction The anionic w~lling agents include alkyll>el~el~c sulfonates, alkyl and dialkylnaphth~l~n~ sulfûnales, alkyl and alcohol sulfates, sulfoalkyl~mi-les, c~l,oAylates, alpha-olefin sulfonates and dialkyl sulfosuccillales. The no~ionic wetting agents include acetylenic diols, ethylene o~cide-propylene o~ide copolymers, alkylpl~ ol etho~ylates, 35 ~i~.ly-lpl~ ûl etho~ylates, fatty acid etho~cylates, alcohol etho~ylates, soll,i 215S86 1~

fatty acid ester ethoxylates and castor oil ethoxylates. The pre~.-cd wetting agents are sodium dialkyl sulfosuccinates of which sodium diisobutyl sulfosuccinate (Molld-.~t¢ MB-100), sodium diamyl sulfosuccin~te and sodium dicyclohexyl sulfosuccinate are more ~e~
S Flow aids can be added to facilitate Ll~lsr~r of th~ dry ingredients from the feed hopper to the tablet die. Suitable flow aids include silica and ~ tom~ceous earth.
A dessic~nt is another optional cc,lllpon~,nl of the formulation of the i~venlioll. As in~ te~l in Example 2 below, a tablet in a sealed conl~in~--without a ~lessi~nt remains er~.~scelll after storage. However, if a dessicant is desirable, it can be r~trm~l to the tablet, or Llcol,uolated into the tablet matri~c.
Tntçm~l desiccants can be those which "rhrmin~lly bind" water in that they undergo chemical re ~ction~ with water to form a new colll~uulld. An example of this type of material is CaO which reacts with water to form Ca(OH)2. Other m~trri~ senl;~;ve of those which react in this manner are mAg.. e~;.. oxide and boric anhydride.
The int~rn~l desir-c~nt can also be of the type which "physically adsorb"
water and are sdected from the group cQ~ ;ng of highly-dis,u~l~ed silicilic acids such as silica gel; ~lnminllm oxide; clays such as montmorillonite; and amorphous and crystalline ~lnminosilir~tes such as molecular sieves and zeolites.
20 Combin~tion~ of these desicc~nt~ with those that form hy~oAides and hydlahs can be used. Kirk-Othmer's Encyclopedia of Chemical Technology (3rd ed., Vol. 8, p 115) desclibes desiccants suitable for use in the tablet formulation of this invention as Type 1 and Type 4 ~l~si~c~nt~ Either type can be employed, singly or in combination, as long as the desiccant does not e~cpand when it picks-25 up water. Such expansion causes the tablet to crack or crumble on long termstorage.
~ ntrrn~l desiccants suitable for the tablet formulation of this invention also include m~teri~l~ that chrmir~lly bind water, not in the sense of a rh~mir~l l~ a~lion that forms a hyd~ ide, but in the sense of a ch~mi~l reaction that 30 produces a hydrate. Repl~s~ ;ve of useful tlesicc~nt~ that form hydrates are CaSO4, NaOAc, MgSO4, Na2SO4, CaC12. and ZnSO4. Repl~selllalive of the hydrate-forming reaction is that undergone by CaC12 to form CaC12-6H20. One or more desiccants from each group, the hydroxide-forming and the hydrate-forming, can be employed, alone or in combination, cl~ p- n.1i.~g on the particular 35 plol,c.Lies sought by the formnl~tQr.

In addition, inert fillers such as sugar or clay can be added as long as they do not affect the ch~m~ stability of the active ingreLe.lt(s). ~teri~l~ such as glid~nts, anti-adl~ nls, and lubricants can also be employed to facilitate production in the tablet press. For e~cample, lllbri~nt~ such as m~
S ~le~le or boric acid can be used. Such lnkri~rnt~ and anti-a Il~ nls can be brushed onto the die surface or ulcol~oralcd into the formnl~tion The tablets are typically pl~altd in the following manner. The solid water-soluble pestici~lç is passed through a 30 mesh screen to remove oversized particles. Granular &~hr<~ous sodium p.,lb(Jl~tC ~ d as described above is 10 blended with the pesti~ide and, if desired, the inert ~ng~-1;P~ i. The blend can be milled, e.g., in an air or h - nmçrmill, or compacted into tablet form wilhoul milling. Blends which are not milled and thereby co,l,plise larger particle sizes are desirable for rapid tablet break-up.
The tablets can be pl~al~d using con~ ;0n~l tablet-making equipment.
15 Their diameter can vary from about 1 cm or less, to 7.5 cm, dep~nr1ing on thetablet weight desired. Flat-faced, beveled-edge p---.-~hf s, with or wilhoul a breakline, produce alll~Clivc tablets.
Tablets are formed in a hydraulic press with a capacilr of 18,000 kg of force. ~l~.Si~ul~.S b~ .~n about 3.43~107 to 6.86~107 Pascals produce tablet 20 which remain intact during storage and h~n-lling and break-up rapidly. Break-up times are l~terminçd by dr~-ng a tablet, typically 7.5 g into 1000 mL of water.The "end point" of final dissolution is dçtçrmin~d by the cess~lio~ of the CL~ ' CS~ ;1 ;o~ ~ .
The tablets described in the following FY~Tnrles were 3.5 cm in diameter, 25 and were made with a hand-o~e.~.ted hydraulic press at a pr~ of 525 kg/cm2.

The following ingredients were milled for 1 minute in a CRC~ analytical labol~lolr mill.
F.amrle 1 2 3 4 Ingredient Wei~ht (g) tlil~. llulull methyl, sodium salt 4.00 4.00 4.00 4.00 al~}.rdlous sodium ~ellJûlale 4.00 4.00 3.52 4.00 des~ic~nt molecular sievesç~tçrn~l 0.48 CaS04 - - -e~ternal W O 94/17660 215 S 8 6 ~ lo PCTrJS94/00068 The milled ingredients, referred to hert,~ r as the pr~mi~çs, were blended well and aged for 3 weeks at 45C in sealed glass jars. In P.~mrles 1 and 4, the molecular sieves and CaS04 were packaged s~dl~lely and added to the glass jars æ çl~tPrn~l dessi~ . The jar co..~ ;ng the premix of P.Y~mple 2 5 conl~led no dessicant, and the premi~ of F.~mple 3 had the molecular sieves incGl~olaled into the formulation. The premi~es were then cooled, and 7.5 g of each premi~ was tabletted. The tablets were added to water and dissolution timeswere measured. The reslllting ~ueous mi~tures were passed through a stack of 50, 100, and 200 mesh screens. Particulate residue was dPtPrminPd by visual 10 i~l~e~ lion of the screens.

F~mrle Dissolution time (min.) Residue Amount 5.25 None 2 4.32 None 3 4.90 Light 4 4.88 None The color suggested the residue was the molecular sieves.

The following ingl~die~ were blended willloul a milling step.

Ingredient Weight (g) tril~c,luron methyl, sodium salt 4.00 a,~dluus sodium pc.l.oldte 4.00 A tablet was made from 7.5 grams of the premi~. The tablet wæ added to 25 water and the dissolution time was --e&~ul~ d. The rçs llting aqueous mi~ture was passed through a stack of 50, 100, and 200 mesh screens. No residue was found upon visual i,l~e~;lion of the screens.

E~ample Dissolution time (min.) Residue Amount 3.80 None 2l5586l The following ingredients were blended, milled and made into a tablet as described in Examples 1-4.
~ Example 6 7 Ingredient Weight (g) Lbc.luloll methyl, sodium salt 4.00 4.00 d~lhyCl~CIuS sodiumpe.l~ol~le 3.98 3.98 catalyst cupric c~l~l.dl~ 0.02 cupric oxide - 0.02 Tablets were made from 7.5 grams of the premixes. The tablets were added to water and the dissolution times were me~,d. The resulting aqueous mi~tures were passed through a stack of 50, 100, and 200 mesh screens.
Particulate residue was det~rmined by visual i,l~eclion of the screens.

p~mple Dissolution time (min.) Residue Amount 6 4.25 None 7 4.92 None lOne thin u ldissol~cd flake was obse.~ed, and it passed through the screens.

Claims (8)

What is claimed is:

1. A tablet formulation comprising, by total weight, about (1) 0.1% to 75% of a water-soluble pesticide that has a melting point of at least 75° and n solubility in PH 7 water at 20°C of at least about 2% by weight, and (2) 25% to 99.9% of an anhydrous metal perborate salt selected from the group sodium, lithium, and potassium per borate having a water content less than about 2% by weight.

2. A tablet formulation according to Claim 1 comprising 10 to 70% of a pesticide and 30 to 90% of a perborate salt.

3. A tablet formulation according to Claim 2 comprising 20 to 60% of a pesticide and 40 to 70% of a perborate salt.

4. A tablet formulation according to Claim 1 wherein the pesticide is selected from at least one member of the group herbicides, fungicides, bactericides, and insecticides.

5. A tablet formulation according to Claim4 wherein the pesticide is a sulfonylurea salt having the formula wherein J is selected from the group , , , , , , or ;

R is selected from the group H and CH3;
R1 is selected from the group F, Cl, Br, NO2, C1-C4 alkyl, C1-C4 haloalkyl, C3-C4 cycloalkyl, C2-C4 haloalkenyl, C1-C4 alkoxy, C1-C4 haloalkoxy, C2-C4 alkoxyalkoxy, CO2R12, C(O)NR13R14, SO2NR15R16, S(O)nR17, C(O)R18, CH2CN and L;
R2 is selected from the group H, F, Cl, Br, CN, CH3, OCH3, SCH3, CF3 and OCF2H;
R3 is selected from the group Cl, NO2, CO2CH3, CO2CH2CH3, SO2N(CH3)2, SO2CH3, SO2CH2CH3, OCH3, and OCH2CH3 R4 is selected from the group C1-C3 alkyl, C1-C2 haloalkyl, C1-C2 alkoxy, C2-C4 haloalkenyl, F, C1, Br, NO2, CO2R12, C(O)NR13R14, SO2NR15R16, S(O)nR17, C(O)R18 and L;
R5 is selected from the group H, F, Cl, Br and CH3;

R6 is selected from the group C1-C3 alkyl, C1-C2 alkoxy, C2-C4 haloalkenyl, F, Cl, Br, CO2R12, C(O)NR13R14, SO2NR15R16, S(O)nR17, C(O)R18 and L;
R7 is selected from the group H, F, Cl, CH3 and CF3;
R8 is selected from the group H, C1-C3 alkyl and pyridyl;
R9 is selected from the group C1-C3 alkyl, C1-C2 alkoxy, F, Cl, Br, NO2, CO2R12, SO2NR15R16, S(O)nR17, OCF2H, C(O)R18, C2-C4 haloalkenyl and L;
R10 is selected from the group H, Cl, F, Br, C1-C3 alkyl and C1-C2 alkoxy;
R11 is selected from the group H, C1-C3 alkyl, C1-C2 alkoxy, C2-C4 haloalkenyl, F, Cl, Br, CO2R12, C(O)NR13R14, SO2NR15R16, S(O)nR17, C(O)R18 and L;
R12 is selected from the group allyl and propargyl and C1-C3 optionally substituted by at least one member independently selected from halogen, C1-C2 alkoxy and CN;
R13 is selected from the group H, C1-C3 alkyl and C1-C2 alkoxy;
R14 is C1-C2 alkyl;
R15 is selected from the group H, C1-C3 alkyl, C1-C2 alkoxy, allyl and cyclopropyl;
R16 is selected from the group H and C1-C3 alkyl;
R17 is selected from the group C1-C3 alkyl, C1-C3 haloalkyl, allyl and propargyl;
R18 is selected from the group C1-C4 alkyl, C1-C4 haloalkyl and C3-C5 cycloalkyl optionally substituted by halogen;
n is 0, 1 or 2;
M is a cation;
L is Rj is selected from the group H and C1-C3 alkyl;
W is selected from the group O and S;
X is selected from the group H, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkoxy, C1-C4 haloalkyl, C1-C4 haloalkylthio, C1-C4 alkylthio, halogen, C2-C5 alkoxyalkyl, C2-C5 alkoxyalkoxy, amino, C1-C3 alkylamino and di(C1-C3 alkyl)amino;
Y is selected from the group H, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkoxy, C1-C4 alkylthio, C1-C4 haloalkylthio, C2-C5 alkoxyalkyl, C2-C5 alkoxyalkoxy, amino, C1-C3 alkylamino, di(C1-C3 alkyl)amino, C3-C4 alkenyloxy, C3-C4 alkynyloxy, C2-C5 alkylthioalkyl, C2-C5 alkylsulfinylalkyl, C2-C5 alkylsulfonylalkyl, C1-C4 haloalkyl, C2-C4 alkynyl, C3-C5 cycloalkyl, azido and cyano;
and Z is selected from the group CH and N;
provided that i) when one or both of X and Y is C1 haloalkoxy, then Z is CH; and ii) when X is halogen, then Z is CH and Y is OCH3, OCH2CH3, N(OCH3)CH3, NHCH3, N(CH3)2 or OCF2H.

6. A tablet formulation according to Claim 5 wherein the metal cation of the sulfonylurea salt is selected from the group sodium, potassium, calcium, magnesium, ammonium and alkylammonium.

7. A tablet formulation according to Claim 6 wherein the sulfonylurea is selected from the group: chlorsulfuron; sulfometuron; chlorimuron ethyl;
metsulfuron methyl; methyl 2-[[[[(4,6-dimethoxy-2-pyrimidinyl)-amino]carbonyl]-amino]sulfonyl]-6-(trifluoromethyl)-3-pyridinecarboxylate;
ethametsulfuron methyl; triasulfuron; ethyl 5-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-amino]sulfonyl]-1-methyl-1H-pyrazole-4-carboxylate; N-[[(4,6-dimethoxy-2-pyrimidinylamino]carbonyl]-3-(ethylsulfonyl)-2-pyridinesulfonamide; thifensulfuron; tribemuron methyl;
bensulfuron methyl; nicosulfuron; methyl 2-[[[[[4,6-bis(difluoromethoxy)-2-pyrimidinyl]amino]carbonyl]amino]sulfonyl]-benzoate;methyl 2-[[[[[4-dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl]amino]-carbonyl]amino]sulfonyl]-3-methylbenzoate; and N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]calbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide.

8. A tablet formulation according to Claim 1 in the form of a tablet.