[go: up one dir, main page]

CA2033070A1 - Vecteurs d'expression du baculovirus - Google Patents

Vecteurs d'expression du baculovirus

Info

Publication number
CA2033070A1
CA2033070A1 CA 2033070 CA2033070A CA2033070A1 CA 2033070 A1 CA2033070 A1 CA 2033070A1 CA 2033070 CA2033070 CA 2033070 CA 2033070 A CA2033070 A CA 2033070A CA 2033070 A1 CA2033070 A1 CA 2033070A1
Authority
CA
Canada
Prior art keywords
promoter
vector
baculovirus
gene
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2033070
Other languages
English (en)
Inventor
Lois K. Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Georgia Research Foundation Inc UGARF
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2033070A1 publication Critical patent/CA2033070A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • C12N15/68Stabilisation of the vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA 2033070 1989-05-17 1990-05-17 Vecteurs d'expression du baculovirus Abandoned CA2033070A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35384789A 1989-05-17 1989-05-17
US353,847 1989-05-17

Publications (1)

Publication Number Publication Date
CA2033070A1 true CA2033070A1 (fr) 1990-11-18

Family

ID=23390826

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2033070 Abandoned CA2033070A1 (fr) 1989-05-17 1990-05-17 Vecteurs d'expression du baculovirus

Country Status (5)

Country Link
EP (1) EP0426840A1 (fr)
JP (1) JPH04501065A (fr)
AU (1) AU631223B2 (fr)
CA (1) CA2033070A1 (fr)
WO (1) WO1990014428A1 (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9106185D0 (en) * 1991-03-22 1991-05-08 Wellcome Found Biological control agents
US6090379A (en) * 1992-04-29 2000-07-18 Boyce Thompson Institute For Plant Research, Inc. Stable pre-occluded virus particle for use in recombinant protein production and pesticides
EP0638124B1 (fr) * 1992-04-29 2003-06-18 Boyce Thompson Institute For Plant Research, Inc. Infection orale de larves d'insecte par des particules pre-occluses de baculovirus
US5593669A (en) * 1992-04-29 1997-01-14 Boyce Thompson Institute For Plant Research, Inc. Stable pre-occluded virus particle
FR2715664B1 (fr) * 1994-01-31 1996-04-12 Proteine Performance Sa Baculovirus recombinant et son utilisation pour la production d'anticorps monoclonaux.
US7326568B2 (en) 1999-02-04 2008-02-05 University Of Georgia Research Foundation, Inc. Recombinant expression of heterologous nucleic acids in protozoa
US6846481B1 (en) 1999-02-04 2005-01-25 University Of Georgia Research Foundation, Inc. Recombinant expression of heterologous nucleic acids in protozoa
US7026156B1 (en) 1999-02-04 2006-04-11 The University Of Georgia Research Foundation, Inc. Diagnostic and protective antigen gene sequences of ichthyophthirius
WO2006069220A2 (fr) 2004-12-22 2006-06-29 Ambrx, Inc. Hormone de croissance humaine modifiee
BRPI0507159A (pt) 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos em feixe de quatro hélices humanos modificados e seus usos
KR20070034512A (ko) 2004-06-18 2007-03-28 암브룩스, 인코포레이티드 신규 항원-결합 폴리펩티드 및 이의 용도
MX2007000728A (es) 2004-07-21 2007-03-15 Ambrx Inc Polipeptidos biosinteticos que utilizan amino acidos no naturalmente codificados.
US8080391B2 (en) 2004-12-22 2011-12-20 Ambrx, Inc. Process of producing non-naturally encoded amino acid containing high conjugated to a water soluble polymer
CA2590429C (fr) 2004-12-22 2014-10-07 Ambrx, Inc. Compositions de synthetase d'aminoacyl-arnt et utilisations correspondantes
CA2594561C (fr) 2004-12-22 2014-12-23 Ambrx, Inc. Formulations d'hormone de croissance humaine comportant un acide amine code de maniere non naturelle
GB2438982A (en) 2004-12-22 2007-12-12 Ambrx Inc Compostions containing, methods involving, and uses of non-natural amino acids and polypeptides
WO2006133088A2 (fr) 2005-06-03 2006-12-14 Ambrx, Inc. Molecules d'interferons humains ameliorees et utilisations de celles-ci
JP4829969B2 (ja) 2005-08-18 2011-12-07 アンブルックス,インコーポレイテッド tRNA組成物、およびその使用
JP2009520949A (ja) 2005-11-16 2009-05-28 アンブルックス,インコーポレイテッド 非天然アミノ酸を含んでいる組成物および方法
PT2061878E (pt) 2006-09-08 2014-04-22 Ambrx Inc Supressor híbrido arnt para células de vertebrados
ES2465473T3 (es) 2006-09-08 2014-06-05 Ambrx, Inc. Transcripción de arnt supresor en células de vertebrado
WO2008030558A2 (fr) 2006-09-08 2008-03-13 Ambrx, Inc. Polypeptide plasmatique humain modifié ou squelettes de fc et leurs utilisations
JP2010523084A (ja) 2007-03-30 2010-07-15 アンブルックス,インコーポレイテッド 修飾fgf−21ポリペプチド
WO2008137471A2 (fr) 2007-05-02 2008-11-13 Ambrx, Inc. Polypeptides d'interféron bêta modifiés et leurs utilisations
KR101656107B1 (ko) 2007-11-20 2016-09-08 암브룩스, 인코포레이티드 변형된 인슐린 폴리펩티드 및 이의 용도
CA2712606A1 (fr) 2008-02-08 2009-08-13 Ambrx, Inc. Polypeptides leptine modifies et leurs utilisations de marburg
NZ591235A (en) 2008-07-23 2012-07-27 Ambrx Inc Modified bovine g-csf polypeptides comprising non natural amino acid and their uses treating infections such as mastitis
DK2337846T3 (en) 2008-09-26 2018-03-12 Ambrx Inc NON-NATURAL AMINO ACID REPLICATION DEPENDENT MICROORGANISMS AND VACCINES
BRPI0919403A2 (pt) 2008-09-26 2017-09-26 Ambrx Inc polipeptídeos modificados de eritropoetina animal e seus usos
PE20121707A1 (es) 2009-12-21 2012-12-17 Ambrx Inc Polipeptidos de somatotropina bovina modificados y sus usos
BR112012015597A2 (pt) 2009-12-21 2017-01-31 Ambrx Inc peptídeos de somatotropina suínos modificados e seus usos
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
KR101963460B1 (ko) 2010-08-17 2019-03-28 암브룩스, 인코포레이티드 변형된 릴랙신 폴리펩타이드 및 그것의 용도
AR083006A1 (es) 2010-09-23 2013-01-23 Lilly Co Eli Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
CN107108710B (zh) 2014-10-24 2022-02-15 百时美施贵宝公司 修饰的fgf-21多肽及其用途
MX2019008449A (es) 2017-02-08 2019-09-09 Bristol Myers Squibb Co Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos.
CN116042720B (zh) * 2023-02-14 2025-09-02 中国科学院武汉病毒研究所 一种转运载体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2631974B1 (fr) * 1988-05-31 1992-12-11 Agronomique Inst Nat Rech Baculovirus modifie, son procede de preparation et son application en tant que vecteur d'expression de genes
AU5187190A (en) * 1989-02-23 1990-09-26 University Of Ottawa Improved baculovirus expression system capable of producing foreign gene proteins at high levels

Also Published As

Publication number Publication date
AU5820790A (en) 1990-12-18
EP0426840A1 (fr) 1991-05-15
AU631223B2 (en) 1992-11-19
WO1990014428A1 (fr) 1990-11-29
JPH04501065A (ja) 1992-02-27

Similar Documents

Publication Publication Date Title
US5244805A (en) Baculovirus expression vectors
AU631223B2 (en) Improved baculovirus expression vectors
EP0549721B1 (fr) Systeme d'expression de baculovirus a promoteurs multiples et production de particules defectives
Tessier et al. Enhanced secretion from insect cells of a foreign protein fused to the honeybee melittin signal peptide
US4745051A (en) Method for producing a recombinant baculovirus expression vector
US5518913A (en) High level recombinant protein production using conditional helper-free adenovirus vector
JP3183877B2 (ja) 修飾バキュロウイルス、その調整方法及びそれの形質発現ベクターとしての適用
JP2644447B2 (ja) ポリペプチドの合成方法
US4879236A (en) Method for producing a recombinant baculovirus expression vector
JP3076833B2 (ja) 修飾されたバクロウイルス、その製造方法及び該バクロウイルスから得られる発現ベクター
WO1999010515A1 (fr) Chromosomes artificiels de baculovirus et procedes d'utilisation
EP0397485A1 (fr) Vecteurs d'expression de baculovirus et leur utilisation pour l'expression de protéines étrangères dans des insectes ou cellules d'insectes
JPH0365191A (ja) スフェロイジン単離dnaおよび組み換え昆虫ポックスウィルス発現ベクター
EP0228036A2 (fr) Méthode de production de polypeptides sélectionnés dans des cellules d'insectes infectées par des virus et polypeptides ainsi isolés
Beljelarskaya A baculovirus expression system for insect cells
AU684799B2 (en) Gene insertion by direct ligation (in vitro)
Van Oers et al. Expression of the Autographa californica nuclear polyhedrosis virus p10 gene: effect of polyhedrin gene expression
WO1995009923A1 (fr) Procede de production de virus eukaryotiques recombines dans des bacteries
US6106825A (en) Entomopoxvirus-vertebrate gene delivery vector and method
WO1999010489A1 (fr) Sequences issues d'insectes et permettant d'ameliorer l'efficacite de secretion de proteines qui ne sont pas secretes dans les cellules eucaryotes
Lee et al. Construction of a Baculovirus expression system using Hyphantria cunea nuclear polyhedrosis virus for eukaryotic cells
Smith et al. Method for producing a recombinant baculovirus expression vector
Hong et al. Comparison of promoter activity of the p10 gene between Bombyx mori nucleopolyhedrovirus variants
Kang et al. Construction of a Novel Recombinant Bombyx mori Nuclear Polyhedrosis Virus Producing the Fluorescent Polyhedra
JPH05301895A (ja) ハイブリッド抗原タンパク質、それを発現する組み換えウイルス、及びその製造方法

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead