CA2030077A1 - Amides et esters azabicyclo utilises comme antagonistes de recepteurs 5-ht - Google Patents

Amides et esters azabicyclo utilises comme antagonistes de recepteurs 5-ht

Info

Publication number: CA2030077A1
Authority: CA; Canada
Prior art keywords: amides; esters; azabicyclo; receptor antagonists; indolyl
Prior art date: 1989-11-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2030077A

Other languages

English (en)

Other versions

CA2030077C (fr

Inventor

Terry Jay Rosen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Corp SRL

Original Assignee

Pfizer Corp SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-17

Filing date

1990-11-15

Publication date

1991-05-18

1990-11-15 Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL

1991-05-18 Publication of CA2030077A1 publication Critical patent/CA2030077A1/fr

1995-08-22 Application granted granted Critical

1995-08-22 Publication of CA2030077C publication Critical patent/CA2030077C/fr

2010-11-15 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

CA002030077A 1989-11-17 1990-11-15 Amides et esters azabicyclo utilises comme antagonistes de recepteurs 5-ht Expired - Fee Related CA2030077C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
USPCT/US89/05097		1989-11-17
PCT/US1989/005097 WO1991007402A1 (fr)	1989-11-17	1989-11-17	Amides et esters azabicyliques antagonistes du recepteur de 5-ht¿3?

Publications (2)

Publication Number	Publication Date
CA2030077A1 true CA2030077A1 (fr)	1991-05-18
CA2030077C CA2030077C (fr)	1995-08-22

Family

ID=22215354

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002030077A Expired - Fee Related CA2030077C (fr)	1989-11-17	1990-11-15	Amides et esters azabicyclo utilises comme antagonistes de recepteurs 5-ht

Country Status (11)

Country	Link
EP (1)	EP0434202B1 (fr)
JP (1)	JPH0699428B2 (fr)
AT (1)	ATE106886T1 (fr)
CA (1)	CA2030077C (fr)
DE (1)	DE69009715T2 (fr)
DK (1)	DK0434202T3 (fr)
ES (1)	ES2055344T3 (fr)
FI (1)	FI922124A0 (fr)
IE (1)	IE63420B1 (fr)
PT (1)	PT95895A (fr)
WO (1)	WO1991007402A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9027111D0 (en) *	1990-12-13	1991-02-06	Raychem Ltd	Circuit protection device
GB9214184D0 (en) *	1992-07-03	1992-08-12	Smithkline Beecham Plc	Pharmaceuticals
FR2699533A1 (fr) *	1992-12-21	1994-06-24	Mouhtaram Mohamed	Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
WO2006069097A2 (fr) *	2004-12-22	2006-06-29	Memory Pharmaceuticals Corporation	Ligands du recepteur alpha-7 nicotinique ainsi que preparation et utilisations de ceux-ci

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3405134A (en) *	1965-08-17	1968-10-08	Colgate Palmolive Co	Quinuclidyl esters of aromatic acids
US4467095A (en) *	1969-02-10	1984-08-21	Fmc Corporation	Anticholinergic compounds
US3563995A (en) *	1969-04-17	1971-02-16	Ian Wellings	Alkyl esters of 1-azabicyclo(2.2.2)oct-2-ene-3-(4 - chloro-3-sulfamoylanilino)-2-carboxylic acid
GB1293446A (en) *	1970-07-23	1972-10-18	Rech S Et D Applic Scient Soge	Quinuclidine derivatives, the preparation thereof and pharmaceutical compositions containing them
FR2531955A1 (fr) *	1982-08-17	1984-02-24	Pharmuka Lab	Nouveau procede de preparation de derives de la quinuclidine substitues en position 3
CH667657A5 (de) *	1985-01-07	1988-10-31	Sandoz Ag	Carbocyclische und heterocyclische carbonylmethylen- und methylpiperidine und -pyrrolidine.
GB8525844D0 (en) *	1985-10-19	1985-11-20	Beecham Group Plc	Compounds
EP0311724A1 (fr) *	1987-10-16	1989-04-19	Synthelabo	R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides et thiobenzamides anxiolytiques

1989
- 1989-11-17 FI FI922124A patent/FI922124A0/fi not_active Application Discontinuation
- 1989-11-17 WO PCT/US1989/005097 patent/WO1991007402A1/fr not_active Ceased
1990
- 1990-11-08 EP EP90312218A patent/EP0434202B1/fr not_active Expired - Lifetime
- 1990-11-08 AT AT90312218T patent/ATE106886T1/de active
- 1990-11-08 ES ES90312218T patent/ES2055344T3/es not_active Expired - Lifetime
- 1990-11-08 DE DE69009715T patent/DE69009715T2/de not_active Expired - Fee Related
- 1990-11-08 DK DK90312218.2T patent/DK0434202T3/da active
- 1990-11-15 CA CA002030077A patent/CA2030077C/fr not_active Expired - Fee Related
- 1990-11-15 PT PT95895A patent/PT95895A/pt not_active Application Discontinuation
- 1990-11-16 JP JP31124190A patent/JPH0699428B2/ja not_active Expired - Lifetime
- 1990-11-16 IE IE413490A patent/IE63420B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0434202T3 (da)	1994-07-04
IE904134A1 (en)	1991-05-22
ES2055344T3 (es)	1994-08-16
ATE106886T1 (de)	1994-06-15
CA2030077C (fr)	1995-08-22
FI922124A7 (fi)	1992-05-11
EP0434202B1 (fr)	1994-06-08
DE69009715T2 (de)	1994-09-22
PT95895A (pt)	1991-09-13
JPH03170480A (ja)	1991-07-24
JPH0699428B2 (ja)	1994-12-07
IE63420B1 (en)	1995-04-19
EP0434202A1 (fr)	1991-06-26
FI922124L (fi)	1992-05-11
DE69009715D1 (de)	1994-07-14
FI922124A0 (fi)	1992-05-11
WO1991007402A1 (fr)	1991-05-30

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Legal Events

Date	Code	Title	Description
1990-11-15	EEER	Examination request
1997-11-17	MKLA	Lapsed