CA2021869A1 - Process for microbiological batch production of l-carnitine - Google Patents
Process for microbiological batch production of l-carnitineInfo
- Publication number
- CA2021869A1 CA2021869A1 CA2021869A CA2021869A CA2021869A1 CA 2021869 A1 CA2021869 A1 CA 2021869A1 CA 2021869 A CA2021869 A CA 2021869A CA 2021869 A CA2021869 A CA 2021869A CA 2021869 A1 CA2021869 A1 CA 2021869A1
- Authority
- CA
- Canada
- Prior art keywords
- carnitine
- microbiological
- batch production
- batch
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 2
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title 1
- 238000010923 batch production Methods 0.000 title 1
- 229960001518 levocarnitine Drugs 0.000 title 1
- 230000002906 microbiologic effect Effects 0.000 title 1
- GUYHPGUANSLONG-SNAWJCMRSA-N (E)-4-(trimethylammonio)but-2-enoate Chemical compound C[N+](C)(C)C\C=C\C([O-])=O GUYHPGUANSLONG-SNAWJCMRSA-N 0.000 abstract 1
- JHPNVNIEXXLNTR-UHFFFAOYSA-O 4-(trimethylammonio)butanoic acid Chemical compound C[N+](C)(C)CCCC(O)=O JHPNVNIEXXLNTR-UHFFFAOYSA-O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Magnetic Record Carriers (AREA)
- Television Signal Processing For Recording (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The process starts from gamma -butyrobetaine and/or crotonobetaine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002021869A CA2021869C (en) | 1989-07-28 | 1990-07-24 | Process for microbiological batch production of l-carnitine |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH2813/89 | 1989-07-28 | ||
| CH281389 | 1989-07-28 | ||
| CA002021869A CA2021869C (en) | 1989-07-28 | 1990-07-24 | Process for microbiological batch production of l-carnitine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2021869A1 true CA2021869A1 (en) | 1991-01-29 |
| CA2021869C CA2021869C (en) | 2000-09-05 |
Family
ID=4242178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002021869A Expired - Lifetime CA2021869C (en) | 1989-07-28 | 1990-07-24 | Process for microbiological batch production of l-carnitine |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0410430B1 (en) |
| JP (1) | JPH0751071B2 (en) |
| AT (1) | ATE132535T1 (en) |
| AU (1) | AU625525B2 (en) |
| BR (1) | BR9003672A (en) |
| CA (1) | CA2021869C (en) |
| DD (1) | DD296702A5 (en) |
| DE (1) | DE59010027D1 (en) |
| DK (1) | DK0410430T3 (en) |
| ES (1) | ES2081878T3 (en) |
| FI (1) | FI102083B (en) |
| IE (1) | IE902689A1 (en) |
| IL (1) | IL95196A (en) |
| MX (1) | MX170707B (en) |
| NO (1) | NO178235C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5759824A (en) * | 1993-10-08 | 1998-06-02 | Lonza, A.G. | Genes for butyrobetaine/crotonobetaine-l-carnitine metabolism and their use for the microbiological production of l-carnitine |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1261230B (en) * | 1993-04-08 | 1996-05-09 | Sigma Tau Ind Farmaceuti | IMPROVED PROCEDURE FOR THE PREPARATION OF L - (-) - CARNITINA STARTING FROM ITS PRECURSORS WITH OPPOSED CONFIGURATION. |
| ZA200704132B (en) * | 2004-11-09 | 2008-09-25 | Univ Stellenbosch | Method of producing a carnitine-synthesising micro-organism |
| KR100713103B1 (en) * | 2005-07-07 | 2007-05-02 | 씨제이 주식회사 | Microorganisms of the genus Enterobacteria containing neurospora Krasa-derived L-carnitine biosynthesis related genes and a method for producing L-carnitine using the same |
| US8604237B2 (en) | 2009-11-18 | 2013-12-10 | Lonza Ltd | Methods for the production of L-carnitine |
| EP2325164A1 (en) | 2009-11-18 | 2011-05-25 | Lonza Ltd. | Methods for the production of l-carnitine |
| KR102329115B1 (en) | 2014-05-30 | 2021-11-19 | 엘지전자 주식회사 | Laundry Treating Apparatus |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59192095A (en) * | 1983-04-13 | 1984-10-31 | Ajinomoto Co Inc | Preparation of l-carnitine |
| FI86889C (en) * | 1984-03-29 | 1992-10-26 | Lonza Ag | Process for the preparation of L-carnitine in a microbiological manner |
| CH664374A5 (en) * | 1985-02-27 | 1988-02-29 | Lonza Ag | METHOD FOR PRODUCING L-CARNITIN BY A MICROBIOLOGICAL WAY. |
-
1990
- 1990-07-24 IE IE268990A patent/IE902689A1/en not_active IP Right Cessation
- 1990-07-24 MX MX021712A patent/MX170707B/en unknown
- 1990-07-24 CA CA002021869A patent/CA2021869C/en not_active Expired - Lifetime
- 1990-07-24 JP JP2196017A patent/JPH0751071B2/en not_active Expired - Fee Related
- 1990-07-25 ES ES90114287T patent/ES2081878T3/en not_active Expired - Lifetime
- 1990-07-25 DK DK90114287.7T patent/DK0410430T3/en active
- 1990-07-25 AT AT90114287T patent/ATE132535T1/en not_active IP Right Cessation
- 1990-07-25 DE DE59010027T patent/DE59010027D1/en not_active Expired - Lifetime
- 1990-07-25 EP EP90114287A patent/EP0410430B1/en not_active Expired - Lifetime
- 1990-07-26 IL IL9519690A patent/IL95196A/en active IP Right Grant
- 1990-07-26 AU AU59837/90A patent/AU625525B2/en not_active Expired
- 1990-07-26 FI FI903742A patent/FI102083B/en active IP Right Grant
- 1990-07-27 NO NO903338A patent/NO178235C/en not_active IP Right Cessation
- 1990-07-27 DD DD90343118A patent/DD296702A5/en not_active IP Right Cessation
- 1990-07-27 BR BR909003672A patent/BR9003672A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5759824A (en) * | 1993-10-08 | 1998-06-02 | Lonza, A.G. | Genes for butyrobetaine/crotonobetaine-l-carnitine metabolism and their use for the microbiological production of l-carnitine |
Also Published As
| Publication number | Publication date |
|---|---|
| IE902689A1 (en) | 1991-02-27 |
| FI903742A0 (en) | 1990-07-26 |
| IL95196A0 (en) | 1991-06-10 |
| JPH0751071B2 (en) | 1995-06-05 |
| BR9003672A (en) | 1991-08-27 |
| IL95196A (en) | 1995-05-26 |
| EP0410430A2 (en) | 1991-01-30 |
| MX170707B (en) | 1993-09-08 |
| NO903338L (en) | 1991-01-29 |
| ES2081878T3 (en) | 1996-03-16 |
| EP0410430A3 (en) | 1991-08-21 |
| EP0410430B1 (en) | 1996-01-03 |
| NO178235B (en) | 1995-11-06 |
| DK0410430T3 (en) | 1996-01-29 |
| NO178235C (en) | 1996-02-14 |
| JPH0376591A (en) | 1991-04-02 |
| CA2021869C (en) | 2000-09-05 |
| FI102083B1 (en) | 1998-10-15 |
| AU625525B2 (en) | 1992-07-16 |
| FI102083B (en) | 1998-10-15 |
| DD296702A5 (en) | 1991-12-12 |
| DE59010027D1 (en) | 1996-02-15 |
| NO903338D0 (en) | 1990-07-27 |
| AU5983790A (en) | 1991-01-31 |
| ATE132535T1 (en) | 1996-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |