CA2009270A1 - Antigene stabilise de l'hepatie e pouvant etre utilise pour des dosages immunologiques - Google Patents

Antigene stabilise de l'hepatie e pouvant etre utilise pour des dosages immunologiques

Info

Publication number: CA2009270A1
Authority: CA; Canada
Prior art keywords: hbeag; hbe; solid support; stabilized; antigen
Prior art date: 1989-02-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA 2009270

Other languages

English (en)

Inventor

Daniel J. Hicklin

Charles T. Tackney

Harlan W. Waksal

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ImClone LLC

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-06

Filing date

1990-02-05

Publication date

1990-08-06

1990-02-05 Application filed by Individual filed Critical Individual

1990-08-06 Publication of CA2009270A1 publication Critical patent/CA2009270A1/fr

Status Abandoned legal-status Critical Current

Links

238000003018 immunoassay Methods 0.000 title claims abstract description 8
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208000006454 hepatitis Diseases 0.000 title abstract description 5
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238000000034 method Methods 0.000 claims abstract description 25
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ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 18
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
- G01N33/5762—Hepatitis B core antigen
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Biochemistry (AREA)
Hematology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Organic Chemistry (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Cell Biology (AREA)
Genetics & Genomics (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

CA 2009270 1989-02-06 1990-02-05 Antigene stabilise de l'hepatie e pouvant etre utilise pour des dosages immunologiques Abandoned CA2009270A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30790089A	1989-02-06	1989-02-06
US307,900		1989-02-06

Publications (1)

Publication Number	Publication Date
CA2009270A1 true CA2009270A1 (fr)	1990-08-06

Family

ID=23191654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA 2009270 Abandoned CA2009270A1 (fr)	1989-02-06	1990-02-05	Antigene stabilise de l'hepatie e pouvant etre utilise pour des dosages immunologiques

Country Status (2)

Country	Link
CA (1)	CA2009270A1 (fr)
WO (1)	WO1990008960A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4107612A1 (de)	1991-03-09	1992-09-10	Behringwerke Ag	Rekombinante proteine mit der immunreaktivitaet des hepatitis b virus e antigens (hbeag), verfahren zu ihrer herstellung und ihre verwendung in immunoassays und impfstoffen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8746582A (en) *	1981-09-02	1983-03-10	Biogen N.V.	Hepatitis b virus e type antigen
JPS5848856A (ja) *	1981-09-17	1983-03-22	Green Cross Corp:The	ＨＢｅＡｇに対する特異抗体の製法及びＨＢｅＡｇの検出試薬
EP0272483A1 (fr) *	1986-12-19	1988-06-29	Abbott Laboratories	Méthodes et moyens pour la production d'HBeAg

1990
- 1990-02-05 CA CA 2009270 patent/CA2009270A1/fr not_active Abandoned
- 1990-02-05 WO PCT/US1990/000657 patent/WO1990008960A1/fr not_active Ceased

Also Published As

Publication number	Publication date
WO1990008960A1 (fr)	1990-08-09

Publication	Publication Date	Title
EP0233045A2 (fr)	1987-08-19	Peptides pour le diagnostic des anticorps HTLV-III, ainsi que leur préparation et leur utilisation
US5183734A (en)	1993-02-02	Antibodies, diagnostic systems and methods for assaying SV40 HBxAg
US5625034A (en)	1997-04-29	Core antigen protein of hepatitis C virus, and diagnostic method and kit using the same
JPH07508411A (ja)	1995-09-21	Ｃｋｓ融合タンパク質の使用方法
JP2634203B2 (ja)	1997-07-23	イムノアツセイおよびそれに使用される生物学的構築体
Feitelson et al.	1990	X antigen/antibody markers in hepadnavirus infections: presence and significance of hepadnavirus X gene product (s) in serum
IE69471B1 (en)	1996-09-18	Method and products for detection of human T cell leukemia virus
US5859185A (en)	1999-01-12	HCMV-specific peptides, agents therefor and the use thereof
US4959323A (en)	1990-09-25	Production and use of pre S polypeptides of hepatitis B virus
US5501948A (en)	1996-03-26	Stabilized hepatitis B e antigen suitable for immunoassays
EP1308730A1 (fr)	2003-05-07	Procede servant a detecter ou a determiner vbh
Baumeister et al.	2000	Hepatitis B virus e antigen specific epitopes and limitations of commercial anti‐HBe immunoassays
EP0272483A1 (fr)	1988-06-29	Méthodes et moyens pour la production d'HBeAg
CA2009270A1 (fr)	1990-08-06	Antigene stabilise de l'hepatie e pouvant etre utilise pour des dosages immunologiques
EP0313986B1 (fr)	1995-12-27	Dosages immunologiques utilisant des antigènes produits dans des organismes hétérologues
DK174060B1 (da)	2002-05-13	Antigent syntetisk polypeptid, vandopløselig eller vanddispergerbar polymer indeholdende polypeptidet, receptormolekyle, der kan immunoreagere dermed, diagnostisk analysesystem til bestemmelse af HBxAg, samt fremgangsmåder til bestemmelse.....
US5744298A (en)	1998-04-28	DNA sequences which encode immunoreactive HCMV-specific peptides
EP0593291A2 (fr)	1994-04-20	Protéine nonstructurale du virus de l'hépatite C, et méthode diagnostique et nécessaire
JPH05508924A (ja)	1993-12-09	エプスタイン―バーウイルス膜抗原に対する哺乳類の抗体応答の検出および／または定量用アッセー
CA2004287A1 (fr)	1990-06-01	Peptide
Usuda et al.	1997	A monoclonal antibody against a hepatitis B e antigen epitope borne by six amino acids encoded by the precore region
WO1991004341A1 (fr)	1991-04-04	Peptide specifiques a hdv
KR19990000562A (ko)	1999-01-15	B형 간염 바이러스의 특이항원인 ub hbv 코어 단백질의 정제방법 및 이를 이용한 핵 항체 단백질의 검출방법
NO177310B (no)	1995-05-15	Antigent polypeptid fra HBxAg, antistoff som reagerer med polypeptidet, diagnostisk analysesystem for bestemmelse av tilstedeværelsen av HBxAg i en kroppspröve, samt anvendelse av polypeptidet til in vitro diagnose

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Date	Code	Title	Description
1998-02-05	FZDE	Dead