CA2093361A1 - Derive porphyrine - Google Patents
Derive porphyrineInfo
- Publication number
- CA2093361A1 CA2093361A1 CA002093361A CA2093361A CA2093361A1 CA 2093361 A1 CA2093361 A1 CA 2093361A1 CA 002093361 A CA002093361 A CA 002093361A CA 2093361 A CA2093361 A CA 2093361A CA 2093361 A1 CA2093361 A1 CA 2093361A1
- Authority
- CA
- Canada
- Prior art keywords
- bonds
- amide
- porphyrin derivative
- rivatives
- photosensitizing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004033 porphyrin derivatives Chemical class 0.000 title 1
- 238000009825 accumulation Methods 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002215 photochemotherapeutic effect Effects 0.000 abstract 1
- 230000002165 photosensitisation Effects 0.000 abstract 1
- 239000003504 photosensitizing agent Substances 0.000 abstract 1
- 150000004032 porphyrins Chemical class 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59386790A | 1990-10-05 | 1990-10-05 | |
| US593,867 | 1990-10-05 | ||
| PCT/CA1991/000346 WO1992006097A1 (fr) | 1990-10-05 | 1991-10-01 | Derives de prophyrine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2093361A1 true CA2093361A1 (fr) | 1992-04-06 |
| CA2093361C CA2093361C (fr) | 2002-04-23 |
Family
ID=24376530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002093361A Expired - Fee Related CA2093361C (fr) | 1990-10-05 | 1991-10-01 | Derive porphyrine |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0553116A1 (fr) |
| AU (1) | AU655942B2 (fr) |
| CA (1) | CA2093361C (fr) |
| MX (1) | MX9101448A (fr) |
| NZ (1) | NZ240057A (fr) |
| WO (1) | WO1992006097A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599924A (en) * | 1992-08-14 | 1997-02-04 | Trustees Of The University Of Pennsylvania | Electron-deficient porphyrins and processes and intermediates for preparing same |
| US5817830A (en) * | 1992-08-14 | 1998-10-06 | Trustees Of The University Of Pennsylvania | Pyrrolic compounds |
| US5371199B1 (en) * | 1992-08-14 | 1995-12-26 | Univ Pennsylvania | Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor |
| US5493017A (en) * | 1992-08-14 | 1996-02-20 | The Trustees Of The University Of Pennsylvania | Ring-metalated porphyrins |
| CA2189967A1 (fr) * | 1994-05-11 | 1995-11-23 | Guy Jacques Felix Marchal | Utilisation de composes a base d'un complexe de porphyrine ou d'un complexe de porphyrine etendue comme preparation diagnostique pour la localisation d'un infarctus |
| US6013241A (en) * | 1995-01-23 | 2000-01-11 | Schering Aktiengesellschaft | Use of porphyrin-complex or expanded porphyrin-complex compounds as an infarction localization diagnosticum |
| US6492420B2 (en) | 1995-03-10 | 2002-12-10 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| US6992107B1 (en) | 1995-03-10 | 2006-01-31 | Photocure Asa | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy |
| CZ291132B6 (cs) * | 1995-03-10 | 2002-12-11 | Photocure Asa | Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem |
| US7530461B2 (en) | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| GB9700396D0 (en) | 1997-01-10 | 1997-02-26 | Photocure As | Photochemotherapeutic compositions |
| GB0018528D0 (en) | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| US6838248B2 (en) | 2000-11-17 | 2005-01-04 | Biomoda, Inc. | Compositions and methods for detecting pre-cancerous conditions in cell and tissue samples using 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine |
| EP1401430A4 (fr) | 2001-05-31 | 2005-10-19 | Miravant Pharm Inc | Derives porphyrine et azaporphyrine substitues et utilisation en therapie photodynamique, radioimagerie, et diagnostic par irm |
| EP2596348B1 (fr) | 2009-07-17 | 2017-09-06 | bioAffinity Technologies, Inc. | Système et procédé d analyse d échantillons marqués au moyen de la 5, 10, 15, 20 tétrakis (4-carboxyphényle) porphine (tcpp) |
| WO2017218959A1 (fr) | 2016-06-16 | 2017-12-21 | Oncoselect Therapeutics, Llc | Composés de porphyrine et compositions utiles pour le traitement du cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675338A (en) * | 1984-07-18 | 1987-06-23 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
| US4693885A (en) * | 1984-07-18 | 1987-09-15 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
| WO1986001720A1 (fr) * | 1984-09-13 | 1986-03-27 | Cytogen Corporation | Conjugues d'agents therapeutiques-anticorps |
| US4656186A (en) * | 1985-04-30 | 1987-04-07 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
| US4886484A (en) * | 1989-06-02 | 1989-12-12 | Litens Automotive Partnership | Torsional spring tensioner with stabilizer |
-
1991
- 1991-10-01 CA CA002093361A patent/CA2093361C/fr not_active Expired - Fee Related
- 1991-10-01 EP EP19910916730 patent/EP0553116A1/fr not_active Withdrawn
- 1991-10-01 AU AU86122/91A patent/AU655942B2/en not_active Ceased
- 1991-10-01 WO PCT/CA1991/000346 patent/WO1992006097A1/fr not_active Ceased
- 1991-10-01 NZ NZ24005791A patent/NZ240057A/en unknown
- 1991-10-04 MX MX9101448A patent/MX9101448A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0553116A1 (fr) | 1993-08-04 |
| AU8612291A (en) | 1992-04-28 |
| NZ240057A (en) | 1994-07-26 |
| CA2093361C (fr) | 2002-04-23 |
| MX9101448A (es) | 1992-06-05 |
| WO1992006097A1 (fr) | 1992-04-16 |
| AU655942B2 (en) | 1995-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |