CA2057049A1 - Membres negatifs dominants de la superfamille de recepteurs steroide/thyroide - Google Patents
Membres negatifs dominants de la superfamille de recepteurs steroide/thyroideInfo
- Publication number
- CA2057049A1 CA2057049A1 CA002057049A CA2057049A CA2057049A1 CA 2057049 A1 CA2057049 A1 CA 2057049A1 CA 002057049 A CA002057049 A CA 002057049A CA 2057049 A CA2057049 A CA 2057049A CA 2057049 A1 CA2057049 A1 CA 2057049A1
- Authority
- CA
- Canada
- Prior art keywords
- receptor
- wild type
- carboxy
- analog
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35869689A | 1989-05-26 | 1989-05-26 | |
| US358,696 | 1989-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2057049A1 true CA2057049A1 (fr) | 1990-11-27 |
Family
ID=23410672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002057049A Abandoned CA2057049A1 (fr) | 1989-05-26 | 1990-05-25 | Membres negatifs dominants de la superfamille de recepteurs steroide/thyroide |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0473716A4 (fr) |
| JP (1) | JPH04506073A (fr) |
| AU (1) | AU639699B2 (fr) |
| CA (1) | CA2057049A1 (fr) |
| WO (1) | WO1990014356A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184256B1 (en) | 1997-04-24 | 2001-02-06 | INSTITUT NATIONAL DE LA SANTé DE LA RECHERCHE MéDICALE | Methods and compositions for use in modulating expression of matrix metalloproteinase genes |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990007517A1 (fr) * | 1988-12-23 | 1990-07-12 | The Salk Institute For Biological Studies | Compositions a activite transcripto-repressive pour des recepteurs et procedes correspondants |
| ES2123569T3 (es) * | 1991-08-08 | 1999-01-16 | Genentech Inc | Regulacion de genes en celulas de mamifero dependiente de ecdiesteroides. |
| US6989242B1 (en) | 1992-02-26 | 2006-01-24 | The General Hospital Coporation | Car receptors and related molecules and methods |
| US5756448A (en) * | 1992-02-26 | 1998-05-26 | The General Hospital Corporation | Constitute activator of retinoid (CAR) receptor polypeptides |
| EP0745121B1 (fr) * | 1992-05-14 | 2007-06-20 | Baylor College Of Medicine | Recepteurs d'hormones steroides mutees, procede d'utilisation et commutateur moleculaire pour therapie genique |
| US6416998B1 (en) * | 1992-09-02 | 2002-07-09 | Baylor College Of Medicine | Plasmid encoding a modified steroid hormone |
| JPH08504325A (ja) * | 1992-10-30 | 1996-05-14 | ザ ゼネラル ホスピタル コーポレーション | 核のホルモン受容体と相互作用するポリペプチド及び関連する分子並びに方法 |
| JP2001504690A (ja) * | 1996-10-29 | 2001-04-10 | バレンティス・インコーポレーテッド | 遺伝子治療用の改変ステロイドホルモン及びそれらの使用法 |
| DE19855013C2 (de) * | 1998-11-20 | 2001-09-13 | Schering Ag | Androgen- und Progesteron-Rezeptor bindendes Hormon Response Element |
| AU2001296354A1 (en) | 2000-09-25 | 2002-04-02 | Baylor College Of Medicine | Improved system for regulation of transgene expression |
| GB201413293D0 (en) | 2014-07-28 | 2014-09-10 | Black & Decker Inc | Mode change knob assembly |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818684A (en) * | 1985-09-10 | 1989-04-04 | The Trustees Of Columbia University In The City Of New York | Auto-anti-idiotypic monoclonal antibodies to steroid receptors and uses thereof |
| US5071773A (en) * | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
| US4981784A (en) * | 1987-12-02 | 1991-01-01 | The Salk Institute For Biological Studies | Retinoic acid receptor method |
| WO1990007517A1 (fr) * | 1988-12-23 | 1990-07-12 | The Salk Institute For Biological Studies | Compositions a activite transcripto-repressive pour des recepteurs et procedes correspondants |
-
1990
- 1990-05-25 WO PCT/US1990/003113 patent/WO1990014356A1/fr not_active Ceased
- 1990-05-25 AU AU58248/90A patent/AU639699B2/en not_active Ceased
- 1990-05-25 JP JP2508846A patent/JPH04506073A/ja active Pending
- 1990-05-25 CA CA002057049A patent/CA2057049A1/fr not_active Abandoned
- 1990-05-25 EP EP19900909272 patent/EP0473716A4/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184256B1 (en) | 1997-04-24 | 2001-02-06 | INSTITUT NATIONAL DE LA SANTé DE LA RECHERCHE MéDICALE | Methods and compositions for use in modulating expression of matrix metalloproteinase genes |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0473716A4 (en) | 1992-09-09 |
| JPH04506073A (ja) | 1992-10-22 |
| AU5824890A (en) | 1990-12-18 |
| AU639699B2 (en) | 1993-08-05 |
| WO1990014356A1 (fr) | 1990-11-29 |
| EP0473716A1 (fr) | 1992-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |