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CA1088068A - Piperidino-quinazolines - Google Patents

Piperidino-quinazolines

Info

Publication number
CA1088068A
CA1088068A CA314,082A CA314082A CA1088068A CA 1088068 A CA1088068 A CA 1088068A CA 314082 A CA314082 A CA 314082A CA 1088068 A CA1088068 A CA 1088068A
Authority
CA
Canada
Prior art keywords
formula
lower alkyl
piperidine
alk
chloroform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA314,082A
Other languages
English (en)
Inventor
Simon F. Campbell
Colin W. Greengrass
John C. Danilewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Application granted granted Critical
Publication of CA1088068A publication Critical patent/CA1088068A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CA314,082A 1977-11-16 1978-10-24 Piperidino-quinazolines Expired CA1088068A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB4758377 1977-11-16
GB47583/77 1977-11-16
IE47583/77 1977-11-16
GB7844533A GB2010824B (en) 1977-11-16 1978-11-15 Therapeutic agents

Publications (1)

Publication Number Publication Date
CA1088068A true CA1088068A (fr) 1980-10-21

Family

ID=26266083

Family Applications (1)

Application Number Title Priority Date Filing Date
CA314,082A Expired CA1088068A (fr) 1977-11-16 1978-10-24 Piperidino-quinazolines

Country Status (12)

Country Link
JP (1) JPS5481282A (fr)
AT (1) AT365183B (fr)
AU (1) AU509348B2 (fr)
BE (1) BE872023A (fr)
CA (1) CA1088068A (fr)
CH (1) CH637131A5 (fr)
DE (1) DE2849392A1 (fr)
FR (1) FR2409267A1 (fr)
GB (1) GB2010824B (fr)
LU (1) LU80531A1 (fr)
NL (1) NL174646C (fr)
SE (1) SE7811770L (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE800178L (en) * 1979-01-31 1980-07-31 Pfizer Ltd Derivatives of 4-amino-2-piperidinoquinazoline
FR2514353A2 (fr) * 1980-04-28 1983-04-15 Synthelabo Derives de piperidine et leur application en therapeutique
FR2481278A1 (fr) * 1980-04-28 1981-10-30 Synthelabo Nouveaux derives de piperidine, leur procede de preparation et leur application en therapeutique
JPS62212385A (ja) * 1986-03-13 1987-09-18 Kotobuki Seiyaku Kk キナゾリン誘導体並びに血圧降下剤及びその製法

Also Published As

Publication number Publication date
NL174646C (nl) 1984-07-16
ATA816678A (de) 1981-05-15
DE2849392A1 (de) 1979-05-23
LU80531A1 (fr) 1980-06-05
CH637131A5 (de) 1983-07-15
AU4157678A (en) 1979-05-24
JPS5623991B2 (fr) 1981-06-03
BE872023A (fr) 1979-05-14
FR2409267B1 (fr) 1981-02-27
GB2010824A (en) 1979-07-04
SE7811770L (sv) 1979-05-17
JPS5481282A (en) 1979-06-28
AT365183B (de) 1981-12-28
NL174646B (nl) 1984-02-16
NL7811236A (nl) 1979-05-18
AU509348B2 (en) 1980-05-08
FR2409267A1 (fr) 1979-06-15
GB2010824B (en) 1982-06-16

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Legal Events

Date Code Title Description
MKEX Expiry