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BRPI1008998A2 - adaptador de inalador para um aparelho de difração de laser e método para medir a distribuição de tamanho de partícula - Google Patents

adaptador de inalador para um aparelho de difração de laser e método para medir a distribuição de tamanho de partícula

Info

Publication number
BRPI1008998A2
BRPI1008998A2 BRPI1008998A BRPI1008998A BRPI1008998A2 BR PI1008998 A2 BRPI1008998 A2 BR PI1008998A2 BR PI1008998 A BRPI1008998 A BR PI1008998A BR PI1008998 A BRPI1008998 A BR PI1008998A BR PI1008998 A2 BRPI1008998 A2 BR PI1008998A2
Authority
BR
Brazil
Prior art keywords
particle size
size distribution
laser diffraction
diffraction apparatus
measuring particle
Prior art date
Application number
BRPI1008998A
Other languages
English (en)
Inventor
Benoit Adamo
Chad C Smutney
Saiyam Shah
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of BRPI1008998A2 publication Critical patent/BRPI1008998A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0211—Investigating a scatter or diffraction pattern
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/02—Equipment for testing the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N2015/025—Methods for single or grouped particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
BRPI1008998A 2009-03-18 2010-03-18 adaptador de inalador para um aparelho de difração de laser e método para medir a distribuição de tamanho de partícula BRPI1008998A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16137909P 2009-03-18 2009-03-18
PCT/US2010/027880 WO2010108046A1 (en) 2009-03-18 2010-03-18 Inhaler adaptor for a laser diffraction apparatus and method for measuring particle size distribution

Publications (1)

Publication Number Publication Date
BRPI1008998A2 true BRPI1008998A2 (pt) 2016-03-22

Family

ID=42224988

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008998A BRPI1008998A2 (pt) 2009-03-18 2010-03-18 adaptador de inalador para um aparelho de difração de laser e método para medir a distribuição de tamanho de partícula

Country Status (13)

Country Link
US (3) US8508732B2 (pt)
EP (1) EP2408499B1 (pt)
JP (1) JP5671519B2 (pt)
KR (1) KR20110139737A (pt)
CN (1) CN102355918B (pt)
AU (1) AU2010226547B2 (pt)
BR (1) BRPI1008998A2 (pt)
CA (2) CA2992927A1 (pt)
DK (1) DK2408499T3 (pt)
IL (1) IL215149A (pt)
MX (1) MX2011009682A (pt)
SG (1) SG174345A1 (pt)
WO (1) WO2010108046A1 (pt)

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
CA2479751C (en) 2002-03-20 2008-06-03 Trent Poole Inhalation apparatus
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
DK1791542T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Diketopiperazinsalte for pharmaceutical delivery
ES2640282T3 (es) 2005-09-14 2017-11-02 Mannkind Corporation Método de formulación de fármacos basado en el aumento de la afinidad de superficies de micropartículas cristalinas para agentes activos
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
ES2904623T3 (es) 2008-06-20 2022-04-05 Mannkind Corp Aparato interactivo para establecer un perfil en tiempo real de esfuerzos de inhalación
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
BRPI1008998A2 (pt) 2009-03-18 2016-03-22 Mannkind Corp adaptador de inalador para um aparelho de difração de laser e método para medir a distribuição de tamanho de partícula
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
KR101940832B1 (ko) 2011-04-01 2019-01-21 맨카인드 코포레이션 의약 카트리지용 블리스터 패키지
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
IN2014DN03093A (pt) 2011-10-24 2015-05-15 Mannkind Corp
BR112015000529B1 (pt) 2012-07-12 2022-01-11 Mannkind Corporation Inalador de pó seco
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
CN103196805B (zh) * 2013-04-02 2015-09-16 青岛众瑞智能仪器有限公司 一种检测气溶胶质量浓度的光学装置
AU2014290438B2 (en) 2013-07-18 2019-11-07 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
GB2521148B (en) * 2013-12-10 2016-06-08 Kind Consumer Ltd Airflow testing apparatus
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN114904100A (zh) 2016-01-29 2022-08-16 曼金德公司 干粉吸入器
BR112018073742B1 (pt) 2016-05-19 2023-12-26 Mannkind Corporation Aparelho acessório de inalador, sistema de monitoramento e detecção, e método de monitoramento e detecção
CN106248542A (zh) * 2016-08-16 2016-12-21 广东欧珀移动通信有限公司 一种检测空气质量的方法、装置及终端
GB201700727D0 (en) 2017-01-16 2017-03-01 Teva Pharma Inhalers and airflow adaptors therefor
AU2018301423A1 (en) 2017-07-11 2020-01-30 Arizona Board Of Regents On Behalf Of Arizona State University Detection and monitoring of dosage delivery for vaporized waxes, solids or viscous oils, and cannabinoids
EP4247337A1 (en) 2020-11-17 2023-09-27 United Therapeutics Corporation Inhaled imatinib for pulmonary hypertension field
WO2024059819A2 (en) 2022-09-15 2024-03-21 Tff Pharmaceuticals, Inc. Compositions of cannabinoids for delivery by inhalation

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NZ217006A (en) 1985-07-30 1989-04-26 Glaxo Group Ltd Inhaler for finely divided medicament includes plunger to open medicament container
US6279511B1 (en) 1998-10-23 2001-08-28 Instech Laboratories, Inc. Powered multichannel infusion and monitoring system
JP3531557B2 (ja) * 1999-11-05 2004-05-31 株式会社島津製作所 レーザ回折・散乱式粒度分布測定装置
US6417920B1 (en) * 1999-05-11 2002-07-09 Shimadzu Corporation Particle size analyzer based on laser diffraction method
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7204250B1 (en) 1999-12-16 2007-04-17 Compumedics Limited Bio-mask
FI20010144A0 (fi) 2001-01-24 2001-01-24 Valtion Teknillinen Menetelmä ja laite aerosolilähteiden tutkimiseksi
SE518397C2 (sv) * 2001-04-05 2002-10-01 Microdrug Ag Förfarande och anordning för frigörande av pulver och inhalatoranordning för administrering av medicinskt pulver
US7414720B2 (en) * 2001-07-27 2008-08-19 Herbert Wachtel Measuring particle size distribution in pharmaceutical aerosols
DE10136555A1 (de) * 2001-07-27 2003-02-13 Boehringer Ingelheim Int Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren
US20080015457A1 (en) 2002-11-07 2008-01-17 Silva Carlos D Device for Monitoring Respiratory Movements
US20070006876A1 (en) 2003-05-16 2007-01-11 University Of Alberta Add-on spacer design concept for dry-powder inhalers
CA2554005C (en) 2004-02-24 2013-05-28 Microdose Technologies, Inc. Directional flow sensor inhaler
US7762953B2 (en) 2005-04-20 2010-07-27 Adidas Ag Systems and methods for non-invasive physiological monitoring of non-human animals
JP2007061281A (ja) 2005-08-30 2007-03-15 Hitachi Ltd 吸入量測定システム
US20090151720A1 (en) 2006-05-10 2009-06-18 S.K.I. Net, Inc. Small animal anesthesia system
WO2008060484A2 (en) * 2006-11-10 2008-05-22 Proveris Scientific Corporation Automated nasal spray pump testing
US8172817B2 (en) * 2007-01-31 2012-05-08 Allegiance Corporation Liquid collection system and related methods
JP2011505925A (ja) 2007-04-11 2011-03-03 スター ライフ サイエンシーズ コーポレイション 移動性の動物用の非侵襲性フォトプレチスモグラフィセンサプラットフォーム
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
WO2010105094A1 (en) * 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
BRPI1008998A2 (pt) 2009-03-18 2016-03-22 Mannkind Corp adaptador de inalador para um aparelho de difração de laser e método para medir a distribuição de tamanho de partícula
US9180263B2 (en) 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device

Also Published As

Publication number Publication date
IL215149A0 (en) 2011-12-29
US9347866B2 (en) 2016-05-24
DK2408499T3 (da) 2014-05-12
AU2010226547A1 (en) 2011-09-22
SG174345A1 (en) 2011-11-28
KR20110139737A (ko) 2011-12-29
EP2408499B1 (en) 2014-03-05
JP2012521220A (ja) 2012-09-13
MX2011009682A (es) 2011-10-17
CA2755514A1 (en) 2010-09-23
IL215149A (en) 2015-04-30
US20100238457A1 (en) 2010-09-23
US9041925B2 (en) 2015-05-26
CA2755514C (en) 2018-03-13
US20150226656A1 (en) 2015-08-13
EP2408499A1 (en) 2012-01-25
CN102355918B (zh) 2014-07-16
US8508732B2 (en) 2013-08-13
CA2992927A1 (en) 2010-09-23
US20130308130A1 (en) 2013-11-21
AU2010226547B2 (en) 2013-09-26
JP5671519B2 (ja) 2015-02-18
WO2010108046A1 (en) 2010-09-23
CN102355918A (zh) 2012-02-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]