BRPI1007155A2 - métodos para tratar um distúrbio neurológico cortical, e para dispensar um agente terapêutico para o córtex em um primata - Google Patents
métodos para tratar um distúrbio neurológico cortical, e para dispensar um agente terapêutico para o córtex em um primataInfo
- Publication number
- BRPI1007155A2 BRPI1007155A2 BRPI1007155A BRPI1007155A BRPI1007155A2 BR PI1007155 A2 BRPI1007155 A2 BR PI1007155A2 BR PI1007155 A BRPI1007155 A BR PI1007155A BR PI1007155 A BRPI1007155 A BR PI1007155A BR PI1007155 A2 BRPI1007155 A2 BR PI1007155A2
- Authority
- BR
- Brazil
- Prior art keywords
- primate
- cortex
- dispensing
- treating
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14830209P | 2009-01-29 | 2009-01-29 | |
| PCT/US2010/022659 WO2010088560A1 (en) | 2009-01-29 | 2010-01-29 | Methods for distributing high levels of therapeutic agent throughout the cortex to treat neurological disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1007155A2 true BRPI1007155A2 (pt) | 2017-05-30 |
Family
ID=41796538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1007155A BRPI1007155A2 (pt) | 2009-01-29 | 2010-01-29 | métodos para tratar um distúrbio neurológico cortical, e para dispensar um agente terapêutico para o córtex em um primata |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11305022B2 (pt) |
| EP (1) | EP2391388A1 (pt) |
| JP (2) | JP2012516357A (pt) |
| CN (1) | CN102369024A (pt) |
| AU (1) | AU2010208058A1 (pt) |
| BR (1) | BRPI1007155A2 (pt) |
| CA (1) | CA2751266A1 (pt) |
| CL (1) | CL2011001845A1 (pt) |
| WO (1) | WO2010088560A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2391388A1 (en) * | 2009-01-29 | 2011-12-07 | University of California-San Francisco | Methods for distributing high levels of therapeutic agent throughout the cortex to treat neurological disorders |
| US20160237141A1 (en) * | 2011-02-10 | 2016-08-18 | Cedars-Sinai Medical Center | Methods of treating alzheimer's disease with apo a-1 milano |
| PT2879719T (pt) * | 2012-08-01 | 2018-10-08 | Ohio State Innovation Foundation | Administração intratecal do vírus adeno-associado 9 recombinante |
| GB201308917D0 (en) * | 2013-05-17 | 2013-07-03 | Renishaw Plc | Delivery |
| WO2015164778A1 (en) | 2014-04-25 | 2015-10-29 | The Trustees Of The University Of Pennysylvania | Ldlr variants and their use in compositions for reducing cholesterol levels |
| LT3137497T (lt) | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| CR20170407A (es) | 2015-02-10 | 2017-11-14 | Genzyme Corp | Mejora del suministro de partículas virales al cuerpo estriado y al córtex |
| CN115957350A (zh) * | 2015-12-11 | 2023-04-14 | 宾夕法尼亚州大学信托人 | 用于治疗家族性高胆固醇血症的基因疗法 |
| WO2018022511A1 (en) | 2016-07-25 | 2018-02-01 | The Trustees Of The University Of Pennsylvania | Compositions comprising a lecithin cholesterol acyltransferase variant and uses thereof |
| US11554147B2 (en) | 2017-02-20 | 2023-01-17 | The Trustees Of The University Of Pennsylvania | Gene therapy for treating familial hypercholesterolemia |
| CN116310602B (zh) * | 2023-01-28 | 2025-08-15 | 华南理工大学 | 胎龄预测方法、装置、介质和设备 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692147A (en) | 1980-04-02 | 1987-09-08 | Medtronic, Inc. | Drug administration device |
| US5139941A (en) | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| AU8200191A (en) | 1990-07-09 | 1992-02-04 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | High efficiency packaging of mutant adeno-associated virus using amber suppressions |
| US5173414A (en) | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| DK0648271T3 (da) | 1991-08-20 | 2003-07-21 | Us Gov Health & Human Serv | Adenovirusmedieret overførsel af gener til mave-/tarmkanal |
| US5735815A (en) | 1993-07-26 | 1998-04-07 | Sentinel Medical, Inc. | Method of using fluid jet surgical cutting tool |
| WO1995005864A1 (en) | 1993-08-27 | 1995-03-02 | Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services | Convection-enhanced drug delivery |
| US5576201A (en) | 1994-01-14 | 1996-11-19 | Alexion Pharmaceuticals, Inc. | Retroviral vector particles for transducing non-proliferating cells |
| US6351659B1 (en) | 1995-09-28 | 2002-02-26 | Brainlab Med. Computersysteme Gmbh | Neuro-navigation system |
| US6109815A (en) | 1995-11-03 | 2000-08-29 | Merlo; Werner O. | Joint mechanism |
| US6042579A (en) | 1997-04-30 | 2000-03-28 | Medtronic, Inc. | Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain |
| EP1621626B1 (en) | 1998-05-27 | 2009-07-08 | Genzyme Corporation | AAV Vectors for the manufacture of medicaments for convection enhanced delivery |
| EP1080202B1 (en) | 1998-05-27 | 2006-01-25 | Avigen, Inc. | Convection-enhanced delivery of aav vectors encoding aadc |
| WO2003004660A1 (en) | 2001-07-03 | 2003-01-16 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods of administering vectors to synaptically connected neurons |
| US20030050273A1 (en) | 2001-08-29 | 2003-03-13 | Keiya Ozawa | Compositions and methods for treating neurodegenerative diseases |
| GB2389791B (en) | 2002-04-30 | 2006-12-13 | Steven Gill | Implantable drug delivery pump |
| EP3067070A1 (en) | 2002-09-24 | 2016-09-14 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Method for convection enhanced delivery of therapeutic agents |
| US20060171926A1 (en) | 2004-04-30 | 2006-08-03 | Passini Marco A | Gene therapy for neurometabolic disorders |
| CA2581714C (en) | 2004-10-05 | 2017-09-12 | Avigen, Inc. | Stepped cannula |
| US20060129126A1 (en) * | 2004-11-19 | 2006-06-15 | Kaplitt Michael G | Infusion device and method for infusing material into the brain of a patient |
| US9089667B2 (en) | 2005-08-23 | 2015-07-28 | The Regents Of The University Of California | Reflux resistant cannula and system for chronic delivery of therapeutic agents using convection-enhanced delivery |
| WO2007127839A2 (en) | 2006-04-26 | 2007-11-08 | The Regents Of The University Of California | Compositions and methods for convection enhanced delivery of high molecular weight neurotherapeutics |
| EP2212348B1 (en) * | 2007-11-02 | 2015-07-15 | Cornell University | Materials and methods for gene mediated therapy of psychiatric disorders |
| EP2391388A1 (en) * | 2009-01-29 | 2011-12-07 | University of California-San Francisco | Methods for distributing high levels of therapeutic agent throughout the cortex to treat neurological disorders |
-
2010
- 2010-01-29 EP EP10703579A patent/EP2391388A1/en not_active Withdrawn
- 2010-01-29 AU AU2010208058A patent/AU2010208058A1/en not_active Abandoned
- 2010-01-29 BR BRPI1007155A patent/BRPI1007155A2/pt not_active IP Right Cessation
- 2010-01-29 CA CA2751266A patent/CA2751266A1/en not_active Abandoned
- 2010-01-29 CN CN2010800109540A patent/CN102369024A/zh active Pending
- 2010-01-29 WO PCT/US2010/022659 patent/WO2010088560A1/en not_active Ceased
- 2010-01-29 JP JP2011548357A patent/JP2012516357A/ja active Pending
- 2010-01-29 US US13/146,640 patent/US11305022B2/en active Active
-
2011
- 2011-07-29 CL CL2011001845A patent/CL2011001845A1/es unknown
-
2015
- 2015-02-02 JP JP2015018554A patent/JP2015083614A/ja not_active Withdrawn
-
2022
- 2022-03-17 US US17/697,841 patent/US12370270B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US11305022B2 (en) | 2022-04-19 |
| CN102369024A (zh) | 2012-03-07 |
| US20220347319A1 (en) | 2022-11-03 |
| CA2751266A1 (en) | 2010-08-05 |
| EP2391388A1 (en) | 2011-12-07 |
| WO2010088560A1 (en) | 2010-08-05 |
| JP2015083614A (ja) | 2015-04-30 |
| AU2010208058A1 (en) | 2011-08-18 |
| CL2011001845A1 (es) | 2012-07-13 |
| US20120027726A1 (en) | 2012-02-02 |
| JP2012516357A (ja) | 2012-07-19 |
| US12370270B2 (en) | 2025-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |