BRPI0821139A2 - Derivados de esteróides agindo como agonistas de receptor de glicocorticosteróides - Google Patents

Derivados de esteróides agindo como agonistas de receptor de glicocorticosteróides

Info

Publication number: BRPI0821139A2
Authority: BR; Brazil
Prior art keywords: receptor agonists; steroid derivatives; derivatives acting; glucocorticosteroid receptor; glucocorticosteroid
Prior art date: 2007-12-20

Application number

BRPI0821139-6A

Other languages

English (en)

Inventor

Hakan Bladh

Karl Edman

Thomas Hansson

Karolina Lawitz

Matti Lepistö

Tesfaledet Mussie

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-20

Filing date

2008-12-18

Publication date

2015-06-16

2008-12-18 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2015-06-16 Publication of BRPI0821139A2 publication Critical patent/BRPI0821139A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Immunology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

BRPI0821139-6A 2007-12-20 2008-12-18 Derivados de esteróides agindo como agonistas de receptor de glicocorticosteróides BRPI0821139A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1540407P	2007-12-20	2007-12-20
PCT/SE2008/051489 WO2009082342A1 (en)	2007-12-20	2008-12-18	Steroid derivatives acting as glucocorticosteroid receptor agonists

Publications (1)

Publication Number	Publication Date
BRPI0821139A2 true BRPI0821139A2 (pt)	2015-06-16

Family

ID=40801455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0821139-6A BRPI0821139A2 (pt)	2007-12-20	2008-12-18	Derivados de esteróides agindo como agonistas de receptor de glicocorticosteróides

Country Status (10)

Country	Link
US (1)	US20110160167A1 (pt)
EP (1)	EP2235037A1 (pt)
JP (1)	JP2011507836A (pt)
KR (1)	KR20100102121A (pt)
CN (1)	CN101945885A (pt)
AU (1)	AU2008341590A1 (pt)
BR (1)	BRPI0821139A2 (pt)
CA (1)	CA2707618A1 (pt)
RU (1)	RU2010124799A (pt)
WO (1)	WO2009082342A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2700181A1 (en)	2007-10-04	2009-04-09	Astrazeneca Ab	Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity
UY32520A (es)	2009-04-03	2010-10-29	Astrazeneca Ab	Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
WO2017132103A2 (en)	2016-01-29	2017-08-03	Merck Sharp & Dohme Corp.	Phosphonate linkers and their use to facilitate cellular retention of compounds
WO2018071736A1 (en) *	2016-10-14	2018-04-19	Van Andel Research Institute	Structures and mechanism for the design of highly potent glucocorticoids
CN110105420A (zh) *	2019-06-04	2019-08-09	博诺康源(北京)药业科技有限公司	一种布地奈德杂质ep-zg的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3129218A (en) *	1961-11-01	1964-04-14	Merck & Co Inc	2-alkoxymethylene steroids of the androstane and pregnane series
US3072639A (en) *	1962-03-05	1963-01-08	Merck & Co Inc	16-oxygenated-4-pregneno-[3, 2-c] pyrazoles and process of preparing them
US3364203A (en) *	1965-09-09	1968-01-16	Syntex Corp	6, 7-methylene and 6, 7-halomethylene pyrazole pregnanes and processes for their preparation
US3471477A (en) *	1967-10-18	1969-10-07	Syntex Corp	6-gem-difluoro (3,2-c) and (2,3-d) pyrazole steroids
DE2735110A1 (de) *	1977-08-04	1979-02-15	Hoechst Ag	Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
DE2817988A1 (de) *	1978-04-25	1979-11-08	Hoechst Ag	Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
SE8306370D0 (sv) *	1983-11-18	1983-11-18	Draco Ab	Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
DE3540537A1 (de) *	1985-11-15	1987-05-21	Klaus Kurt Koelzer	Verstaerkungsmaterial
WO2005063777A1 (en) *	2003-12-23	2005-07-14	Corus Pharma	Benzylphosphate and substituted benzylphosphate prodrugs for the treatment of pulmonary inflammation
CA2700181A1 (en) *	2007-10-04	2009-04-09	Astrazeneca Ab	Steroidal [3, 2-c] pyrazole compounds, with glucocorticoid activity
UY32525A (es) *	2009-04-03	2010-10-29	Astrazeneca Ab	Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32520A (es) *	2009-04-03	2010-10-29	Astrazeneca Ab	Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides
UY32523A (es) *	2009-04-03	2010-10-29	Astrazeneca Ab	Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32521A (es) *	2009-04-03	2010-10-29	Astrazeneca Ab	Combinación para emplear en el tratamiento de enfermedades respiratorias

2008
- 2008-12-18 CN CN2008801268528A patent/CN101945885A/zh active Pending
- 2008-12-18 EP EP08863416A patent/EP2235037A1/en not_active Withdrawn
- 2008-12-18 KR KR1020107013463A patent/KR20100102121A/ko not_active Withdrawn
- 2008-12-18 WO PCT/SE2008/051489 patent/WO2009082342A1/en not_active Ceased
- 2008-12-18 JP JP2010539381A patent/JP2011507836A/ja active Pending
- 2008-12-18 BR BRPI0821139-6A patent/BRPI0821139A2/pt not_active IP Right Cessation
- 2008-12-18 AU AU2008341590A patent/AU2008341590A1/en not_active Abandoned
- 2008-12-18 RU RU2010124799/04A patent/RU2010124799A/ru unknown
- 2008-12-18 CA CA2707618A patent/CA2707618A1/en not_active Abandoned
- 2008-12-18 US US12/809,131 patent/US20110160167A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20110160167A1 (en)	2011-06-30
WO2009082342A1 (en)	2009-07-02
JP2011507836A (ja)	2011-03-10
CA2707618A1 (en)	2009-07-02
AU2008341590A1 (en)	2009-07-02
CN101945885A (zh)	2011-01-12
KR20100102121A (ko)	2010-09-20
EP2235037A1 (en)	2010-10-06
RU2010124799A (ru)	2012-01-27

Publication	Publication Date	Title
BRPI0820447A2 (pt)	2015-05-26	Agonistas do receptor de glicocorticóides
BRPI0817562A2 (pt)	2017-05-02	derivados de n-hidroxilsulfonamida como novos doadores de niltroxil fisiologicamente úteis
ATE524460T1 (de)	2011-09-15	Pyridon-gpr119-g-protein-gekoppelte rezeptoragonisten
BRPI0911563A2 (pt)	2016-07-12	uso de antagonista da progesterona
BRPI0817245A2 (pt)	2015-06-16	Derivados e quinolina como antagonistas receptores de 5ht5a
EP2350060A4 (en)	2012-07-25	Melanocortin receptor AGONISTS
BR112012000107A2 (pt)	2016-11-01	receptores de células t.
BRPI0716936A2 (pt)	2013-09-17	derivados de adenosina como antigonistas de receptor de a2a
BRPI0810613A2 (pt)	2017-05-09	derivados de tetra-hidrocarbazol como ligantes de receptores acoplados à proteína g
DK2401269T3 (da)	2014-04-28	Indolderivater som crth2-receptorantagonister
BRPI0810462A2 (pt)	2014-10-14	Derivados de quinolina-carboxamida como antagonistas de p2y12
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
DK2081951T3 (da)	2010-08-09	Progesteron-receptorantagonister
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
BRPI0821141A2 (pt)	2015-06-16	Derivados de heteroarila como antagonistas do receptor de orexina
BRPI0909157A2 (pt)	2015-11-24	compostos heterocíclicos como antagonistas de receptores de adenosina
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
BRPI0717023A2 (pt)	2014-03-11	Tiazol pirazolopirimidina como antagonistas do receptor de crf1
BRPI0812518A2 (pt)	2015-03-31	Derivados de indazolamida
BRPI0820649A2 (pt)	2015-06-16	Derivados de isoxazalo-pirazina
BRPI0820805A2 (pt)	2015-06-16	Antagonista do receptor de mineralocorticóides derivados da 6h-di-benzo[b,e]oxepina
BRPI0717937A2 (pt)	2013-12-03	Compostos de pirazona como antagonistas do receptor mineralocorticóide
BRPI0817061A2 (pt)	2015-03-24	Derivados de pirrolidinilalquilisoquinolinona e -isoindolinona como antagonistas de histamina-3

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.