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BRPI0813372A2 - Fator vii/viia humano modificado, ácido nucléico, vetor de expressão, célula transformada por um ácido nucleico, organismo não humano geneticamente modificado, processo de fabricação de um fator vii/viia, composição de fator vii/viia, composição farmacêutica, e, utilização de um fator vii/viia. - Google Patents

Fator vii/viia humano modificado, ácido nucléico, vetor de expressão, célula transformada por um ácido nucleico, organismo não humano geneticamente modificado, processo de fabricação de um fator vii/viia, composição de fator vii/viia, composição farmacêutica, e, utilização de um fator vii/viia.

Info

Publication number
BRPI0813372A2
BRPI0813372A2 BRPI0813372-7A2A BRPI0813372A BRPI0813372A2 BR PI0813372 A2 BRPI0813372 A2 BR PI0813372A2 BR PI0813372 A BRPI0813372 A BR PI0813372A BR PI0813372 A2 BRPI0813372 A2 BR PI0813372A2
Authority
BR
Brazil
Prior art keywords
viia
composition
factor vii
nucleic acid
human
Prior art date
Application number
BRPI0813372-7A2A
Other languages
English (en)
Inventor
Emmanuel Nony
Sami Chtourou
Nicolas Bihoreau
Original Assignee
Lfb Biotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lfb Biotechnologies filed Critical Lfb Biotechnologies
Publication of BRPI0813372A2 publication Critical patent/BRPI0813372A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6437Coagulation factor VIIa (3.4.21.21)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21021Coagulation factor VIIa (3.4.21.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
BRPI0813372-7A2A 2007-06-15 2008-06-12 Fator vii/viia humano modificado, ácido nucléico, vetor de expressão, célula transformada por um ácido nucleico, organismo não humano geneticamente modificado, processo de fabricação de um fator vii/viia, composição de fator vii/viia, composição farmacêutica, e, utilização de um fator vii/viia. BRPI0813372A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0755775A FR2917414B1 (fr) 2007-06-15 2007-06-15 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci
PCT/FR2008/051055 WO2008155509A2 (fr) 2007-06-15 2008-06-12 Facteur vii/viia humain modifie et composition pharmaceutique contenant celui-ci

Publications (1)

Publication Number Publication Date
BRPI0813372A2 true BRPI0813372A2 (pt) 2014-12-30

Family

ID=38702010

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813372-7A2A BRPI0813372A2 (pt) 2007-06-15 2008-06-12 Fator vii/viia humano modificado, ácido nucléico, vetor de expressão, célula transformada por um ácido nucleico, organismo não humano geneticamente modificado, processo de fabricação de um fator vii/viia, composição de fator vii/viia, composição farmacêutica, e, utilização de um fator vii/viia.

Country Status (12)

Country Link
US (1) US20110162094A1 (pt)
EP (1) EP2162147A2 (pt)
JP (1) JP2010529848A (pt)
KR (1) KR20100039281A (pt)
CN (1) CN101743017A (pt)
AR (1) AR067335A1 (pt)
AU (1) AU2008265021A1 (pt)
BR (1) BRPI0813372A2 (pt)
CA (1) CA2691110A1 (pt)
FR (1) FR2917414B1 (pt)
TW (1) TW200906851A (pt)
WO (1) WO2008155509A2 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2554161A1 (en) 2011-08-02 2013-02-06 LFB Biotechnologies Pharmaceutical composition comprising factor VII encapsulated in micelles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000007I2 (de) * 1986-04-09 2010-12-30 Genzyme Corp Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern
DK323587D0 (da) * 1987-06-25 1987-06-25 Novo Industri As Protein
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2684999A1 (fr) * 1991-12-16 1993-06-18 Aquitaine Dev Transf Sanguine Procede de fabrication d'un concentre de facteur vii active de haute purete essentiellement depourvu des facteurs vitamine k dependants et des facteurs viiic et viiicag.
US7173000B2 (en) * 2000-11-09 2007-02-06 The Scripps Research Institute Modified factor VIIa

Also Published As

Publication number Publication date
EP2162147A2 (fr) 2010-03-17
AU2008265021A1 (en) 2008-12-24
CA2691110A1 (fr) 2008-12-24
FR2917414B1 (fr) 2012-07-13
JP2010529848A (ja) 2010-09-02
FR2917414A1 (fr) 2008-12-19
TW200906851A (en) 2009-02-16
US20110162094A1 (en) 2011-06-30
WO2008155509A9 (fr) 2010-04-08
KR20100039281A (ko) 2010-04-15
AR067335A1 (es) 2009-10-07
WO2008155509A2 (fr) 2008-12-24
WO2008155509A3 (fr) 2009-02-19
CN101743017A (zh) 2010-06-16

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.