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BRPI0812161A2 - Processo para a preparação do derivado de dibenzo[b,d]azepin-6-ona - Google Patents

Processo para a preparação do derivado de dibenzo[b,d]azepin-6-ona

Info

Publication number
BRPI0812161A2
BRPI0812161A2 BRPI0812161-3A2A BRPI0812161A BRPI0812161A2 BR PI0812161 A2 BRPI0812161 A2 BR PI0812161A2 BR PI0812161 A BRPI0812161 A BR PI0812161A BR PI0812161 A2 BRPI0812161 A2 BR PI0812161A2
Authority
BR
Brazil
Prior art keywords
azepin
ona
dibenzo
derivative
preparing
Prior art date
Application number
BRPI0812161-3A2A
Other languages
English (en)
Inventor
Fabienne Hoffmann-Emery
Roland Jakob-Roetne
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0812161A2 publication Critical patent/BRPI0812161A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/08—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0812161-3A2A 2007-05-25 2008-05-15 Processo para a preparação do derivado de dibenzo[b,d]azepin-6-ona BRPI0812161A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07108904 2007-05-25
PCT/EP2008/055937 WO2008145525A2 (en) 2007-05-25 2008-05-15 Process for the preparation of dibenzo [b,d]azepin-6-one derivative

Publications (1)

Publication Number Publication Date
BRPI0812161A2 true BRPI0812161A2 (pt) 2014-12-16

Family

ID=39776364

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812161-3A2A BRPI0812161A2 (pt) 2007-05-25 2008-05-15 Processo para a preparação do derivado de dibenzo[b,d]azepin-6-ona

Country Status (12)

Country Link
US (1) US7579464B2 (pt)
EP (1) EP2164830B1 (pt)
JP (2) JP5745841B2 (pt)
KR (1) KR101494918B1 (pt)
CN (1) CN101679278B (pt)
AU (1) AU2008257734B2 (pt)
BR (1) BRPI0812161A2 (pt)
CA (1) CA2686645C (pt)
ES (1) ES2422602T3 (pt)
IL (1) IL202016A (pt)
MX (1) MX2009012277A (pt)
WO (1) WO2008145525A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7579464B2 (en) * 2007-05-25 2009-08-25 Hoffmann-La Roche Inc. Process for preparation of enantiomerically pure compounds
WO2014047370A1 (en) 2012-09-21 2014-03-27 Bristol-Myers Squibb Company Fluoroalkyl dibenzodiazepinone compounds
KR102130458B1 (ko) * 2015-10-30 2020-07-08 파이프라인 테라퓨틱스, 아이엔씨. 디벤조 아제핀 화합물 및 귀 질환과 귀 장애 치료에서의 그의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3008227B2 (ja) * 1991-12-18 2000-02-14 第一製薬株式会社 メンチル ｎ−（２−フルオロシクロプロピル）カルバメート誘導体及びその製法
US6528505B1 (en) 1998-06-22 2003-03-04 Elan Pharmaceuticals, Inc. Cyclic amino acid compounds pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
AU2002211233A1 (en) * 2000-09-18 2002-03-26 E.I. Du Pont De Nemours And Company Pyridinyl amides and imides for use as fungicides
NZ541324A (en) * 2003-02-04 2008-10-31 Hoffmann La Roche Malonamide derivatives as gamma-secretase inhibitors
DE602004020680D1 (de) * 2003-09-09 2009-05-28 Hoffmann La Roche Die aktivität von gamma-secretase blockierende malonamidderivate
DE10341699A1 (de) 2003-09-10 2005-04-28 Symrise Gmbh & Co Kg Verfahren zur Herstellung unsymmetrischer Kohlensäureester
KR100867035B1 (ko) * 2003-10-06 2008-11-04 에프. 호프만-라 로슈 아게 감마-세크레타제 저해제로서 유용한 치환된다이벤조-아제핀 및 벤조-다이아제핀 유도체
KR20070099031A (ko) * 2005-01-25 2007-10-08 셀진 코포레이션 4-아미노-2-(3-메틸-2,6-디옥소피페리딘-3-일)-이소인돌-1,3-디온을 사용한 방법 및 조성물
US7579464B2 (en) * 2007-05-25 2009-08-25 Hoffmann-La Roche Inc. Process for preparation of enantiomerically pure compounds

Also Published As

Publication number Publication date
WO2008145525A3 (en) 2009-08-13
CN101679278B (zh) 2013-08-14
EP2164830B1 (en) 2013-05-29
MX2009012277A (es) 2009-11-25
CA2686645A1 (en) 2008-12-04
WO2008145525A2 (en) 2008-12-04
IL202016A (en) 2014-11-30
AU2008257734B2 (en) 2012-12-06
KR101494918B1 (ko) 2015-02-23
CN101679278A (zh) 2010-03-24
CA2686645C (en) 2015-05-05
JP2010527955A (ja) 2010-08-19
US20080293933A1 (en) 2008-11-27
AU2008257734A1 (en) 2008-12-04
JP2014037431A (ja) 2014-02-27
EP2164830A2 (en) 2010-03-24
IL202016A0 (en) 2010-06-16
US7579464B2 (en) 2009-08-25
JP5745841B2 (ja) 2015-07-08
ES2422602T3 (es) 2013-09-12
KR20100016476A (ko) 2010-02-12

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2514 DE 12-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.