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BRPI0810081A2 - Agente terapêutico e agente diagnóstico para doenças cerebrais de disfunção mitocondrial - Google Patents

Agente terapêutico e agente diagnóstico para doenças cerebrais de disfunção mitocondrial

Info

Publication number
BRPI0810081A2
BRPI0810081A2 BRPI0810081-0A2A BRPI0810081A BRPI0810081A2 BR PI0810081 A2 BRPI0810081 A2 BR PI0810081A2 BR PI0810081 A BRPI0810081 A BR PI0810081A BR PI0810081 A2 BRPI0810081 A2 BR PI0810081A2
Authority
BR
Brazil
Prior art keywords
agent
brain diseases
therapeutic agent
diagnostic
diagnostic agent
Prior art date
Application number
BRPI0810081-0A2A
Other languages
English (en)
Inventor
Toshihiko Kuroiwa
Yoshinaga Kajimoto
Takahiro Masubuchi
Masahiro Ishizuka
Tohru Tanaka
Original Assignee
Sbi Alapromo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sbi Alapromo Co Ltd filed Critical Sbi Alapromo Co Ltd
Publication of BRPI0810081A2 publication Critical patent/BRPI0810081A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/295Iron group metal compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0810081-0A2A 2007-04-05 2008-03-27 Agente terapêutico e agente diagnóstico para doenças cerebrais de disfunção mitocondrial BRPI0810081A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007099508A JP5098051B2 (ja) 2007-04-05 2007-04-05 ミトコンドリア障害脳疾患治療剤及び診断剤
PCT/JP2008/055959 WO2008126693A1 (ja) 2007-04-05 2008-03-27 ミトコンドリア障害脳疾患治療剤及び診断剤

Publications (1)

Publication Number Publication Date
BRPI0810081A2 true BRPI0810081A2 (pt) 2014-10-21

Family

ID=39863800

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810081-0A2A BRPI0810081A2 (pt) 2007-04-05 2008-03-27 Agente terapêutico e agente diagnóstico para doenças cerebrais de disfunção mitocondrial

Country Status (11)

Country Link
US (2) US20100120916A1 (pt)
EP (2) EP2135613B1 (pt)
JP (1) JP5098051B2 (pt)
KR (2) KR101383418B1 (pt)
CN (1) CN101678047B (pt)
AU (1) AU2008239234B2 (pt)
BR (1) BRPI0810081A2 (pt)
CA (1) CA2682855C (pt)
NZ (1) NZ580138A (pt)
RU (1) RU2435595C2 (pt)
WO (1) WO2008126693A1 (pt)

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Publication number Priority date Publication date Assignee Title
EP3192506B1 (en) * 2008-10-27 2024-12-11 SBI Pharmaceuticals Co., Ltd. Prophylactic/ameliorating agent for adult diseases comprising 5-aminolevulinic acid, derivative of 5-aminolevulinic acid, or salt of 5-aminolevulinic acid or the derivative or 5-aminolevulinic acid as active ingredient
JP5574329B2 (ja) * 2010-05-06 2014-08-20 国立大学法人 岡山大学 ミトコンドリアの蛍光染色方法
JPWO2012067152A1 (ja) * 2010-11-16 2014-05-12 三菱化学株式会社 EndothelialProteinCReceptor蛋白質による脳梗塞の検査方法
EP2722041B1 (en) * 2011-06-16 2018-10-24 SBI Pharmaceuticals Co., Ltd. Therapeutic agent for allergic rhinitis
AU2013291455B2 (en) * 2012-07-19 2016-07-21 Sbi Pharmaceuticals Co., Ltd. Prophylactic/therapeutic agent for influenza virus infection
WO2014092051A1 (ja) * 2012-12-11 2014-06-19 国立大学法人熊本大学 核磁気共鳴診断剤、及び、それを用いた、対象内の細胞、組織又は臓器の状態を検出又は診断する方法
HK1224205A1 (zh) * 2013-10-29 2017-08-18 学校法人东京农业大学 共济蛋白增强剂
JP6602651B2 (ja) * 2015-11-24 2019-11-06 Sbiファーマ株式会社 神経発達障害改善剤
US10675242B2 (en) * 2016-09-02 2020-06-09 Sbi Pharmaceuticals, Co., Ltd. Aqueous formulation containing 5-aminolevulinic acid or the like
US10590496B2 (en) * 2016-11-29 2020-03-17 Wedea Inc. Composition for preventing and treating degenerative brain disease using novel lactic acid bacteria
KR102007980B1 (ko) * 2016-11-29 2019-08-06 (주) 위디어 신규 유산균을 이용한 퇴행성 뇌질환 예방 및 치료용 조성물
JP7113434B2 (ja) * 2017-05-31 2022-08-05 Sbiファーマ株式会社 過活動膀胱の予防剤または治療剤
JP7104037B2 (ja) * 2017-06-23 2022-07-20 Sbiファーマ株式会社 神経障害を改善するための医薬組成物
RU2693627C2 (ru) * 2017-11-03 2019-07-03 Общество С Ограниченной Ответственностью "Валента - Интеллект" Комбинации эдаравона для лечения ишемических повреждений мозга
AU2018371152B2 (en) * 2017-11-22 2024-02-08 Khondrion Ip B.V. Novel compounds for use in treating depression and migraine
JP6717989B2 (ja) 2018-02-05 2020-07-08 テラ・ストーン株式会社 細胞内でのatp産生を賦活するための補酵素因子の使用
TW202313061A (zh) 2018-02-05 2023-04-01 日商泰拉強石股份有限公司 包含去氮黃素并睪固酮化合物或去氮黃素并膽固醇化合物的醫藥組成物
CA3097840A1 (en) * 2018-04-20 2019-10-24 Fondazione Telethon Mir-181 inhibitors and uses thereof
CN113260358A (zh) * 2018-12-20 2021-08-13 普惠德生技股份有限公司 含有亚铁胺基酸螯合物粒子的组合物用于制备治疗或减缓神经受损相关疾病的医药品的用途
RU2744453C2 (ru) * 2019-09-02 2021-03-09 Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) Таргетная неинвазивная трансплантация в мозг функционально активных митохондрий для лечения нейродегенеративных заболеваний
WO2022158591A1 (ja) * 2021-01-25 2022-07-28 学校法人順天堂 肥大型心筋症治療剤

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Also Published As

Publication number Publication date
US8927532B2 (en) 2015-01-06
KR20130004943A (ko) 2013-01-14
KR101250576B1 (ko) 2013-04-03
CA2682855C (en) 2015-06-23
RU2009136582A (ru) 2011-04-10
CN101678047B (zh) 2013-05-22
EP3281642A1 (en) 2018-02-14
US20130011337A1 (en) 2013-01-10
EP3281642B1 (en) 2019-05-01
KR20100014718A (ko) 2010-02-10
EP2135613A1 (en) 2009-12-23
CA2682855A1 (en) 2008-10-23
RU2435595C2 (ru) 2011-12-10
US20100120916A1 (en) 2010-05-13
WO2008126693A1 (ja) 2008-10-23
JP2008255059A (ja) 2008-10-23
CN101678047A (zh) 2010-03-24
NZ580138A (en) 2011-04-29
AU2008239234B2 (en) 2012-11-08
KR101383418B1 (ko) 2014-04-08
AU2008239234A1 (en) 2008-10-23
EP2135613B1 (en) 2017-11-22
EP2135613A4 (en) 2010-07-21
JP5098051B2 (ja) 2012-12-12

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SBI PHARMACEUTICALS CO., LTD. (JP)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: A61K 33/26 , A61K 31/197 , A61K 49/00 , A61P 9/00 , A61P 9/10 , A61P 21/00 , A61P 25/00 , A61P 25/06 , A61P 25/16 , A61P 25/24 , A61P 25/28 , A61P 43/00

Ipc: A61K 49/00 (1980.01), A61P 21/00 (2000.01), A61P 2

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]