BRPI0817579A2 - Derivados de tiazol - Google Patents

Derivados de tiazol

Info

Publication number: BRPI0817579A2
Authority: BR; Brazil
Prior art keywords: thiazol derivatives; thiazol; derivatives
Prior art date: 2007-10-05

Application number

Other languages

English (en)

Inventor

Kai Schiemann

Melanie Schultz

Andree Blaukat

Ingo Kober

Wolfgang Staehle

Original Assignee

Merck Patent Ges Mit Beschränkter Haftung

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-05

Filing date

2008-09-19

Publication date

2015-04-07

2008-09-19 Application filed by Merck Patent Ges Mit Beschränkter Haftung filed Critical Merck Patent Ges Mit Beschränkter Haftung

2015-04-07 Publication of BRPI0817579A2 publication Critical patent/BRPI0817579A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0817579 2007-10-05 2008-09-19 Derivados de tiazol BRPI0817579A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102007047735A DE102007047735A1 (de)	2007-10-05	2007-10-05	Thiazolderivate
PCT/EP2008/007894 WO2009046842A2 (de)	2007-10-05	2008-09-19	Thialzolderivate zur behandlung von krebs

Publications (1)

Publication Number	Publication Date
BRPI0817579A2 true BRPI0817579A2 (pt)	2015-04-07

Family

ID=40418145

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0817579 BRPI0817579A2 (pt)	2007-10-05	2008-09-19	Derivados de tiazol

Country Status (16)

Country	Link
US (1)	US8557824B2 (pt)
EP (1)	EP2209777B1 (pt)
JP (2)	JP2010540580A (pt)
KR (1)	KR20100080836A (pt)
CN (1)	CN101815714A (pt)
AR (1)	AR068658A1 (pt)
AU (1)	AU2008310068B2 (pt)
BR (1)	BRPI0817579A2 (pt)
CA (1)	CA2701525C (pt)
DE (1)	DE102007047735A1 (pt)
EA (1)	EA201000550A1 (pt)
ES (1)	ES2548525T3 (pt)
IL (1)	IL204563A (pt)
MX (1)	MX2010003365A (pt)
WO (1)	WO2009046842A2 (pt)
ZA (1)	ZA201003123B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5337711B2 (ja) *	2007-01-25	2013-11-06	イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー	殺菌性アミド
DE102009049211A1 (de) *	2009-10-13	2011-04-28	Merck Patent Gmbh	Sulfoxide
ES2587856T3 (es)	2011-03-18	2016-10-27	Ono Pharmaceutical Co., Ltd.	Derivado de tetrahidrocarbolina
HRP20210957T1 (hr)	2013-11-22	2021-09-17	Sabre Therapeutics Llc	Spojevi inhibitori autotaksina
US9051320B1 (en)	2014-08-18	2015-06-09	Pharmakea, Inc.	Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor
GB201501870D0 (en)	2015-02-04	2015-03-18	Cancer Rec Tech Ltd	Autotaxin inhibitors
GB201502020D0 (en)	2015-02-06	2015-03-25	Cancer Rec Tech Ltd	Autotaxin inhibitory compounds
EP4026549A1 (en)	2015-05-27	2022-07-13	Sabre Therapeutics LLC	Autotaxin inhibitors and uses thereof
WO2016197009A1 (en)	2015-06-05	2016-12-08	Vertex Pharmaceuticals Incorporated	Triazoles for the treatment of demyelinating diseases
WO2018106646A1 (en)	2016-12-06	2018-06-14	Vertex Pharmaceuticals Incorporated	Aminotriazoles for the treatment of demyelinating diseases
WO2018106643A1 (en)	2016-12-06	2018-06-14	Vertex Pharmaceuticals Incorporated	Heterocyclic azoles for the treatment of demyelinating diseases
WO2018106641A1 (en)	2016-12-06	2018-06-14	Vertex Pharmaceuticals Incorporated	Pyrazoles for the treatment of demyelinating diseases
WO2020244539A1 (zh) *	2019-06-04	2020-12-10	江苏恒瑞医药股份有限公司	吡啶酮类衍生物、其制备方法及其在医药上的应用
US11427558B1 (en)	2019-07-11	2022-08-30	ESCAPE Bio, Inc.	Indazoles and azaindazoles as LRRK2 inhibitors
CN113493453B (zh) *	2020-04-07	2023-06-16	江苏恒瑞医药股份有限公司	稠合芳香环类衍生物、其制备方法及其在医药上的应用
WO2022164249A1 (ko) *	2021-01-29	2022-08-04	주식회사 티씨노바이오사이언스	엑토뉴클레오티드 피로포스파타아제-포스포디에스터라아제의 저해 활성을 갖는 신규한 벤조트리아졸 유도체 및 이들의 용도

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5747469A (en)	1991-03-06	1998-05-05	Board Of Regents, The University Of Texas System	Methods and compositions comprising DNA damaging agents and p53
EP0858457A1 (de)	1995-10-20	1998-08-19	Dr. Karl Thomae GmbH	5-gliedrige heterocyclen, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung
GB9904387D0 (en)	1999-02-25	1999-04-21	Pharmacia & Upjohn Spa	Antitumour synergistic composition
AU4972900A (en)	1999-04-08	2000-11-14	Arch Development Corporation	Use of anti-vegf antibody to enhance radiation in cancer therapy
GB0230162D0 (en)	2002-12-24	2003-02-05	Metris Therapeutics Ltd	Compounds useful in inhibiting angiogenesis
FR2856685B1 (fr) *	2003-06-25	2005-09-23	Merck Sante Sas	Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
CA2564139A1 (en) *	2004-04-13	2005-12-08	Arena Pharmaceuticals, Inc.	Modulators of human g protein-coupled receptors for the treatment of hyperglycemia and related disorders
EP1637529A1 (en)	2004-09-20	2006-03-22	4Sc Ag	Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof
US7601745B2 (en) *	2004-09-27	2009-10-13	4Sc Ag	Heterocyclic NF-kB inhibitors
TW200738701A (en) *	2005-07-26	2007-10-16	Du Pont	Fungicidal carboxamides
MX2008002061A (es)	2005-08-18	2008-04-16	Hoffmann La Roche	Derivados de tiazolil piperidina utiles como moduladores del receptor h3.
EP1990332A1 (en)	2006-02-28	2008-11-12	Idemitsu Kosan Co., Ltd.	Naphthacene derivative and organic electroluminescent device using same
EP1832586A1 (en)	2006-03-10	2007-09-12	Oridis Biomed Forschungs- und Entwicklungs GmbH	Thiazole-piperidine derivatives in treatment of diseases of liver and the pancreas
CN101405278A (zh) *	2006-03-15	2009-04-08	4Sc股份公司	新颖的杂环NF-κB抑制剂
EP1834954A1 (en) *	2006-03-15	2007-09-19	4Sc Ag	Thiazoles as NF-kB Inhibitors (proteasome inhibitors)
US7638541B2 (en)	2006-12-28	2009-12-29	Metabolex Inc.	5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine

2007
- 2007-10-05 DE DE102007047735A patent/DE102007047735A1/de not_active Withdrawn
2008
- 2008-09-19 EP EP08802403.9A patent/EP2209777B1/de not_active Not-in-force
- 2008-09-19 BR BRPI0817579 patent/BRPI0817579A2/pt not_active IP Right Cessation
- 2008-09-19 CA CA2701525A patent/CA2701525C/en not_active Expired - Fee Related
- 2008-09-19 ES ES08802403.9T patent/ES2548525T3/es active Active
- 2008-09-19 KR KR1020107009914A patent/KR20100080836A/ko not_active Withdrawn
- 2008-09-19 EA EA201000550A patent/EA201000550A1/ru unknown
- 2008-09-19 MX MX2010003365A patent/MX2010003365A/es not_active Application Discontinuation
- 2008-09-19 JP JP2010527350A patent/JP2010540580A/ja active Pending
- 2008-09-19 US US12/681,724 patent/US8557824B2/en not_active Expired - Fee Related
- 2008-09-19 WO PCT/EP2008/007894 patent/WO2009046842A2/de not_active Ceased
- 2008-09-19 CN CN200880110188A patent/CN101815714A/zh active Pending
- 2008-09-19 AU AU2008310068A patent/AU2008310068B2/en not_active Ceased
- 2008-10-03 AR ARP080104329A patent/AR068658A1/es unknown
2010
- 2010-03-16 IL IL204563A patent/IL204563A/en active IP Right Grant
- 2010-05-04 ZA ZA2010/03123A patent/ZA201003123B/en unknown
2014
- 2014-07-14 JP JP2014144141A patent/JP5843930B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MX2010003365A (es)	2010-04-30
JP5843930B2 (ja)	2016-01-13
AU2008310068A1 (en)	2009-04-16
US20100240676A1 (en)	2010-09-23
EP2209777A2 (de)	2010-07-28
CN101815714A (zh)	2010-08-25
AR068658A1 (es)	2009-11-25
DE102007047735A1 (de)	2009-04-09
JP2010540580A (ja)	2010-12-24
ES2548525T3 (es)	2015-10-19
IL204563A0 (en)	2010-11-30
EP2209777B1 (de)	2015-07-29
KR20100080836A (ko)	2010-07-12
AU2008310068B2 (en)	2014-05-01
CA2701525C (en)	2016-06-28
IL204563A (en)	2017-03-30
WO2009046842A2 (de)	2009-04-16
CA2701525A1 (en)	2009-04-16
JP2014240392A (ja)	2014-12-25
WO2009046842A3 (de)	2009-06-25
ZA201003123B (en)	2011-04-28
EA201000550A1 (ru)	2010-10-29
US8557824B2 (en)	2013-10-15

Publication	Publication Date	Title
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
DK2209786T3 (da)	2013-06-03	Pyrimidinsubstituerede purinderivater
ATE475662T1 (de)	2010-08-15	Dihydropyrazolopyrimidinonderivate
BRPI0817579A2 (pt)	2015-04-07	Derivados de tiazol
ATE483711T1 (de)	2010-10-15	Spiroindolinonderivate
ATE469905T1 (de)	2010-06-15	Pyridopyrimidinonderivate
ATE512135T1 (de)	2011-06-15	Spiroindolinonderivate
DK2134708T3 (da)	2011-08-29	3-Cyano-4-(4-tetrahydropyranphenyl)-pyridin-2-on-derivater
BRPI0813836A2 (pt)	2015-01-06	Derivados pirazólicos
DK2035394T3 (da)	2009-10-05	2-pyrazincarboxamidderivater
BRPI0814236A2 (pt)	2015-01-06	Derivados de quinazolinamida
BRPI0812518A2 (pt)	2015-03-31	Derivados de indazolamida
EP2226315A4 (en)	2012-01-25	2-aminoquinazoline DERIVATIVE
BRPI0818457A2 (pt)	2015-04-14	Derivados de oxadiazol
BRPI0820649A2 (pt)	2015-06-16	Derivados de isoxazalo-pirazina
EP2193127A4 (en)	2011-09-14	BENZOTHIAZOLE COMPOUNDS
BRPI0816461A2 (pt)	2015-03-24	Derivados fungicidas de 2-alquiltio-2-quinolonolóxi-acetamida
DK2152370T3 (da)	2011-08-15	Aryletherpyridazinonderivater
EP2072519A4 (en)	2009-10-21	DIARYLKETIMINDERIVAT
ATE544764T1 (de)	2012-02-15	5-hydroxymethyloxazolidin-2-onderivate

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 6A E 7A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.