BRPI0816705A2 - 6-PYRIMIDINYL-PYRIMID-2-ONA DERIVATIVE - Google Patents

6-PYRIMIDINYL-PYRIMID-2-ONA DERIVATIVE

Info

Publication number: BRPI0816705A2
Authority: BR; Brazil
Prior art keywords: pyrimid; ona; pyrimidinyl; derivative; ona derivative
Prior art date: 2007-09-14

Application number

Other languages

Portuguese (pt)

Inventor

Kenji Fukunaga

Kazutoshi Watanabe

Pascal Barneoud

Jesus Benavides

Jeremy Pratt

Original Assignee

Mitsubishi Tanabe Pharma Corp

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-14

Filing date

2008-09-12

Publication date

2015-03-17

2008-01-11 Priority claimed from EP08290028A external-priority patent/EP2078717A1/en

2008-09-12 Application filed by Mitsubishi Tanabe Pharma Corp, Sanofi Aventis filed Critical Mitsubishi Tanabe Pharma Corp

2015-03-17 Publication of BRPI0816705A2 publication Critical patent/BRPI0816705A2/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Obesity (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Dermatology (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0816705 2007-09-14 2008-09-12 6-PYRIMIDINYL-PYRIMID-2-ONA DERIVATIVE BRPI0816705A2 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2007269485		2007-09-14
JP2007275713		2007-09-25
EP08290028A EP2078717A1 (en)	2008-01-11	2008-01-11	6-Pyrimidinyl-pyrimid-2-one derivative
PCT/JP2008/066936 WO2009035162A1 (en)	2007-09-14	2008-09-12	6-pyrimidinyl-pyrimid-2-one derivative

Publications (1)

Publication Number	Publication Date
BRPI0816705A2 true BRPI0816705A2 (en)	2015-03-17

Family

ID=39874051

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0816705 BRPI0816705A2 (en)	2007-09-14	2008-09-12	6-PYRIMIDINYL-PYRIMID-2-ONA DERIVATIVE

Country Status (15)

Country	Link
US (2)	US8198437B2 (en)
EP (1)	EP2193129B1 (en)
JP (1)	JP5249320B2 (en)
KR (1)	KR20100074182A (en)
CN (1)	CN101883770A (en)
AR (1)	AR068439A1 (en)
AU (1)	AU2008297817A1 (en)
BR (1)	BRPI0816705A2 (en)
CA (1)	CA2698819A1 (en)
EA (1)	EA201070367A1 (en)
MX (1)	MX2010002765A (en)
NZ (1)	NZ584277A (en)
TW (1)	TW200927134A (en)
WO (1)	WO2009035162A1 (en)
ZA (1)	ZA201002213B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200813015A (en) *	2006-03-15	2008-03-16	Mitsubishi Pharma Corp	2-(cyclic amino)-pyrimidone derivatives
AR068439A1 (en)	2007-09-14	2009-11-18	Mitsubishi Tanabe Pharma Corp	DERIVED FROM 6-PIRIMIDINIL-PIRIMID-2-ONA
TW201043618A (en)	2009-03-10	2010-12-16	Sanofi Aventis	Intermediate compound for synthesizing pharmaceutical agent and production method thereof
JP5442852B2 (en) *	2009-08-13	2014-03-12	田辺三菱製薬株式会社	Pyrimidone derivatives as tau protein kinase 1 inhibitors
WO2011019090A1 (en)	2009-08-13	2011-02-17	Mitsubishi Tanabe Pharma Corporation	Pyrimidone derivatives used as tau protein kinase 1 inhibitors
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP3453706A1 (en)	2017-09-08	2019-03-13	Basf Se	Pesticidal imidazole compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2116460A1 (en)	1993-03-02	1994-09-03	Mitsubishi Chemical Corporation	Preventive or therapeutic agents for alzheimer's disease, a screening method of alzheimer's disease and tau-protein kinase i originated from human being
CN100488958C (en) *	2001-09-21	2009-05-20	三菱制药株式会社	3-substituted-4-pyrimidone derivatives
KR100754596B1 (en) *	2001-09-21	2007-09-05	미쯔비시 웰 파마 가부시키가이샤	3-substituted-4-pyrimidone derivatives
TWI357408B (en) *	2003-03-26	2012-02-01	Mitsubishi Tanabe Pharma Corp	3-substituted-4-pyrimidone derivatives
AR050865A1 (en) *	2004-09-09	2006-11-29	Sanofi Aventis	DERIVATIVES OF 2- MORFOLINO-4-PIRIMIDONA
KR20070057931A (en) *	2004-09-29	2007-06-07	미쯔비시 웰 파마 가부시키가이샤	6- (Pyridinyl) -4-pyrimidone derivatives as tau protein kinase 1 inhibitors
TW200740779A (en)	2005-07-22	2007-11-01	Mitsubishi Pharma Corp	Intermediate compound for synthesizing pharmaceutical agent and production method thereof
TW200813015A (en)	2006-03-15	2008-03-16	Mitsubishi Pharma Corp	2-(cyclic amino)-pyrimidone derivatives
AR064660A1 (en) *	2006-12-26	2009-04-15	Mitsubishi Tanabe Pharma Corp	DERIVATIVES OF PIRIMIDINONA 6-HETEROCICLICA 2-REPLACED, MEDICINES THAT CONTAIN THEM AND USES TO PREVENT AND / OR TREAT NEURODEGENERATIVE DISEASES BETWEEN OTHER
AR068439A1 (en)	2007-09-14	2009-11-18	Mitsubishi Tanabe Pharma Corp	DERIVED FROM 6-PIRIMIDINIL-PIRIMID-2-ONA
AR076014A1 (en)	2009-04-02	2011-05-11	Sanofi Aventis	DERIVATIVES OF 3- (1,4) OXAZEPAN -4-PIRIMIDONA

2008
- 2008-09-12 AR ARP080103982A patent/AR068439A1/en not_active Application Discontinuation
- 2008-09-12 US US12/677,213 patent/US8198437B2/en not_active Expired - Fee Related
- 2008-09-12 WO PCT/JP2008/066936 patent/WO2009035162A1/en not_active Ceased
- 2008-09-12 KR KR1020107008065A patent/KR20100074182A/en not_active Withdrawn
- 2008-09-12 EP EP08831179A patent/EP2193129B1/en active Active
- 2008-09-12 CN CN2008801137447A patent/CN101883770A/en active Pending
- 2008-09-12 JP JP2010510582A patent/JP5249320B2/en not_active Expired - Fee Related
- 2008-09-12 TW TW097135175A patent/TW200927134A/en unknown
- 2008-09-12 MX MX2010002765A patent/MX2010002765A/en not_active Application Discontinuation
- 2008-09-12 CA CA2698819A patent/CA2698819A1/en not_active Abandoned
- 2008-09-12 NZ NZ584277A patent/NZ584277A/en not_active IP Right Cessation
- 2008-09-12 BR BRPI0816705 patent/BRPI0816705A2/en not_active IP Right Cessation
- 2008-09-12 AU AU2008297817A patent/AU2008297817A1/en not_active Abandoned
- 2008-09-12 EA EA201070367A patent/EA201070367A1/en unknown
2010
- 2010-03-29 ZA ZA2010/02213A patent/ZA201002213B/en unknown
2012
- 2012-05-09 US US13/467,302 patent/US8518939B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP5249320B2 (en)	2013-07-31
CA2698819A1 (en)	2009-03-19
ZA201002213B (en)	2011-06-29
MX2010002765A (en)	2010-05-19
EP2193129B1 (en)	2012-10-24
US20110021773A1 (en)	2011-01-27
NZ584277A (en)	2011-11-25
US8518939B2 (en)	2013-08-27
TW200927134A (en)	2009-07-01
WO2009035162A1 (en)	2009-03-19
AU2008297817A1 (en)	2009-03-19
KR20100074182A (en)	2010-07-01
EP2193129A1 (en)	2010-06-09
US8198437B2 (en)	2012-06-12
EA201070367A1 (en)	2010-08-30
CN101883770A (en)	2010-11-10
US20120252812A1 (en)	2012-10-04
AR068439A1 (en)	2009-11-18
JP2010538969A (en)	2010-12-16

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FR24C1047I2 (en)	2025-10-10	4-PYRIMIDINESULFAMIDE DERIVATIVE
EP2226315A4 (en)	2012-01-25	2-AMINOQUINAZOLINE DERIVATIVE
BRPI0813707A2 (en)	2014-12-30	PYRIMIDINYL-PYRIDAZINONE DERIVATIVES
BRPI0820112A2 (en)	2015-05-05	ISOXAZOL-PYRIDINE DERIVATIVES
BRPI0809992A2 (en)	2014-10-14	PYROLOPYRIMIDINE DERIVATIVES
BRPI0820113A2 (en)	2015-05-05	ISOXAZOLE-PYRIDAZINE DERIVATIVES
EP2376493A4 (en)	2012-05-30	DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVE
EP2380877A4 (en)	2012-06-27	PYRIDINE-3-CARBOXYAMIDE DERIVATIVE
BRPI0812155A2 (en)	2019-09-24	spiroindolinone derivatives
BRPI0817935A2 (en)	2015-04-07	BIARILLE DERIVATIVES
DK2209786T3 (en)	2013-06-03	PYRIMIDINE-SUBSTITUTED PURINDER DERIVATIVES
EP2170350A4 (en)	2011-09-28	SUBSTITUTED IMIDAZOHETEROCYCLES
ATE542825T1 (en)	2012-02-15	SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES
BRPI0818380A2 (en)	2014-10-07	HERBICIDE-PROTECTOR COMBINATION
BRPI0813836A2 (en)	2015-01-06	PYRAZOLIC DERIVATIVES
BRPI0812518A2 (en)	2015-03-31	INDAZOLAMIDE DERIVATIVES
BRPI0814236A2 (en)	2015-01-06	QUINAZOLINAMIDE DERIVATIVES
EP2072519A4 (en)	2009-10-21	DIARYLCETTIMINE DERIVATIVE
BRPI0820649A2 (en)	2015-06-16	Isoxazalo-pyrazine derivatives
EP2336132A4 (en)	2012-03-21	MORPHOLINOPURIN DERIVATIVE
DK2152370T3 (en)	2011-08-15	Aryletherpyridazinone derivatives
AT505058A3 (en)	2008-12-15	TÜRSCHLIESSSYSTEM
BRPI0814718A2 (en)	2015-02-24	ISOXAZOL-IMIDAZOL DERIVATIVES
ATE546446T1 (en)	2012-03-15	5-AMINOCYCLYLMETHYL-OXAZOLIDINE-2-ONE DERIVATIVE
BRPI0816705A2 (en)	2015-03-17	6-PYRIMIDINYL-PYRIMID-2-ONA DERIVATIVE

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.