BRPI0816571A2 - "composto, processo para preparação do composto, composição farmacêutica, agente e método para o tratamento de uma doença ou uma desordem do sistema nervoso central relacionada à ou afetada pelo recptor 5-ht6" - Google Patents
"composto, processo para preparação do composto, composição farmacêutica, agente e método para o tratamento de uma doença ou uma desordem do sistema nervoso central relacionada à ou afetada pelo recptor 5-ht6"Info
- Publication number
- BRPI0816571A2 BRPI0816571A2 BRPI0816571A BRPI0816571A BRPI0816571A2 BR PI0816571 A2 BRPI0816571 A2 BR PI0816571A2 BR PI0816571 A BRPI0816571 A BR PI0816571A BR PI0816571 A BRPI0816571 A BR PI0816571A BR PI0816571 A2 BRPI0816571 A2 BR PI0816571A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutically acceptable
- compounds
- receptor
- disorder
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- 108091005435 5-HT6 receptors Proteins 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000035475 disorder Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 210000003169 central nervous system Anatomy 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000030814 Eating disease Diseases 0.000 abstract 1
- 208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 201000011529 cardiovascular cancer Diseases 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 235000014632 disordered eating Nutrition 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 208000014951 hematologic disease Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2433CH2007 | 2007-10-26 | ||
| PCT/IN2008/000281 WO2009053997A1 (en) | 2007-10-26 | 2008-05-02 | Amino arylsulfonamide compounds and their use as 5-ht6 ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0816571A2 true BRPI0816571A2 (pt) | 2015-12-22 |
Family
ID=39769531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0816571A BRPI0816571A2 (pt) | 2007-10-26 | 2008-05-02 | "composto, processo para preparação do composto, composição farmacêutica, agente e método para o tratamento de uma doença ou uma desordem do sistema nervoso central relacionada à ou afetada pelo recptor 5-ht6" |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7964627B2 (pt) |
| EP (1) | EP2200980B9 (pt) |
| JP (1) | JP5236001B2 (pt) |
| KR (1) | KR101268654B1 (pt) |
| CN (1) | CN101835748B (pt) |
| AT (1) | ATE518833T1 (pt) |
| AU (1) | AU2008315309B2 (pt) |
| BR (1) | BRPI0816571A2 (pt) |
| CA (1) | CA2703157C (pt) |
| CY (1) | CY1112181T1 (pt) |
| DK (1) | DK2200980T3 (pt) |
| EA (1) | EA017154B1 (pt) |
| ES (1) | ES2370680T3 (pt) |
| HR (1) | HRP20110780T2 (pt) |
| IL (1) | IL205231A (pt) |
| MX (1) | MX2010003765A (pt) |
| NZ (1) | NZ585374A (pt) |
| SI (1) | SI2200980T1 (pt) |
| WO (1) | WO2009053997A1 (pt) |
| ZA (1) | ZA201002165B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102153884B (zh) * | 2011-02-16 | 2013-06-19 | 连云港清泰化工有限公司 | 一种墨水型染料及其制备方法与用途 |
| EP3718547A1 (en) | 2011-10-03 | 2020-10-07 | The University of Utah Research Foundation | Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome |
| CA2862363C (en) * | 2012-02-02 | 2021-06-08 | Joan M. Fallon | Enzyme compositions and use thereof for wound healing |
| EP3083588B1 (en) | 2013-12-20 | 2020-12-09 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| KR101938408B1 (ko) * | 2014-08-16 | 2019-01-14 | 수벤 라이프 사이언시스 리미티드 | 1-[(2-브로모페닐) 술포닐]-5-메톡시-3-[(4-메틸-1-피페라지닐) 메틸]-1h-인돌 디메실레이트 모노히드레이트의 활성 대사산물 및 상기 활성 대사산물의 디메실레이트 디히드레이트 염 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| WO1999002502A2 (en) | 1997-07-11 | 1999-01-21 | Smithkline Beecham Plc | Sulphonamide derivatives being 5-ht6 receptor antagonists and process for their preparation |
| DE69906397T2 (de) * | 1998-01-16 | 2004-02-19 | F. Hoffmann-La Roche Ag | Benzosulfonderivate |
| GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| CA2370147C (en) | 1999-04-21 | 2009-07-28 | Allelix Biopharmaceuticals Inc. | Piperidine-indole compounds having 5-ht6 affinity |
| GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
| ATE340795T1 (de) | 2001-01-30 | 2006-10-15 | Lilly Co Eli | Benzolsulfonsäureester-indol-5-yl als 5-ht6 rezeptor-antagonisten |
| US7342021B2 (en) | 2001-02-08 | 2008-03-11 | Memory Pharmaceuticals Corp. | Phosphodiesterase 4 inhibitors |
| YU96103A (sh) | 2001-06-07 | 2006-08-17 | F.Hoffmann-La Roche Ag. | Novi derivati indola sa afinitetom za 5-ht6 receptor |
| JP2005528587A (ja) | 2002-02-01 | 2005-09-22 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 新規ヒト５−ｈｔ６受容体に関連する疾患のための診断用および治療用物質 |
| JP2005522432A (ja) | 2002-02-05 | 2005-07-28 | グラクソ グループ リミテッド | ニューロン成長の促進方法 |
| BRPI0308696B8 (pt) | 2002-03-27 | 2021-05-25 | Axovant Sciences Gmbh | composto derivado de quinolina, seu processo de preparação, sua composição farmacêutica e seus usos |
| EP1556037B1 (en) | 2002-10-18 | 2006-11-02 | F. Hoffmann-La Roche Ag | 4-piperazinyl benzenesulfonyl indoles with 5-ht6 receptor affinity |
| CN1720227A (zh) * | 2002-11-28 | 2006-01-11 | 苏文生命科学有限公司 | N－芳基磺酰基－3－氨基烷氧基吲哚 |
| AU2003237599B2 (en) | 2002-11-28 | 2009-06-18 | Suven Life Sciences Limited | N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them |
| AU2003292508A1 (en) * | 2002-11-28 | 2004-06-18 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| CA2507923C (en) * | 2002-12-18 | 2010-02-02 | Suven Life Sciences Limited | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
| EP1919896B1 (en) * | 2005-08-12 | 2009-12-23 | Suven Life Sciences Limited | Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands. |
-
2008
- 2008-05-02 EA EA201070527A patent/EA017154B1/ru not_active IP Right Cessation
- 2008-05-02 US US12/682,596 patent/US7964627B2/en not_active Expired - Fee Related
- 2008-05-02 KR KR1020107010395A patent/KR101268654B1/ko not_active Expired - Fee Related
- 2008-05-02 CN CN2008801127356A patent/CN101835748B/zh not_active Expired - Fee Related
- 2008-05-02 EP EP08776656A patent/EP2200980B9/en active Active
- 2008-05-02 HR HRP20110780TT patent/HRP20110780T2/hr unknown
- 2008-05-02 CA CA2703157A patent/CA2703157C/en not_active Expired - Fee Related
- 2008-05-02 AU AU2008315309A patent/AU2008315309B2/en not_active Ceased
- 2008-05-02 JP JP2010530633A patent/JP5236001B2/ja active Active
- 2008-05-02 SI SI200830420T patent/SI2200980T1/sl unknown
- 2008-05-02 NZ NZ585374A patent/NZ585374A/en not_active IP Right Cessation
- 2008-05-02 AT AT08776656T patent/ATE518833T1/de active
- 2008-05-02 MX MX2010003765A patent/MX2010003765A/es active IP Right Grant
- 2008-05-02 BR BRPI0816571A patent/BRPI0816571A2/pt active Search and Examination
- 2008-05-02 WO PCT/IN2008/000281 patent/WO2009053997A1/en not_active Ceased
- 2008-05-02 ES ES08776656T patent/ES2370680T3/es active Active
- 2008-05-02 DK DK08776656.4T patent/DK2200980T3/da active
-
2010
- 2010-03-26 ZA ZA2010/02165A patent/ZA201002165B/en unknown
- 2010-04-21 IL IL205231A patent/IL205231A/en active IP Right Grant
-
2011
- 2011-11-03 CY CY20111101058T patent/CY1112181T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20110780T2 (hr) | 2018-06-29 |
| CA2703157C (en) | 2013-02-05 |
| KR101268654B1 (ko) | 2013-05-29 |
| CY1112181T1 (el) | 2015-12-09 |
| AU2008315309B2 (en) | 2011-06-09 |
| EP2200980B9 (en) | 2011-12-28 |
| KR20100069707A (ko) | 2010-06-24 |
| EA201070527A1 (ru) | 2010-10-29 |
| EP2200980B1 (en) | 2011-08-03 |
| NZ585374A (en) | 2011-09-30 |
| CN101835748B (zh) | 2012-11-14 |
| AU2008315309A1 (en) | 2009-04-30 |
| SI2200980T1 (sl) | 2011-12-30 |
| ZA201002165B (en) | 2011-05-25 |
| WO2009053997A1 (en) | 2009-04-30 |
| IL205231A (en) | 2014-03-31 |
| CA2703157A1 (en) | 2009-04-30 |
| MX2010003765A (es) | 2010-04-30 |
| US7964627B2 (en) | 2011-06-21 |
| ES2370680T3 (es) | 2011-12-21 |
| EA017154B1 (ru) | 2012-10-30 |
| ATE518833T1 (de) | 2011-08-15 |
| IL205231A0 (en) | 2010-12-30 |
| DK2200980T3 (da) | 2011-11-21 |
| HRP20110780T1 (hr) | 2011-11-30 |
| JP2011500792A (ja) | 2011-01-06 |
| CN101835748A (zh) | 2010-09-15 |
| US20100216861A1 (en) | 2010-08-26 |
| HK1147750A1 (en) | 2011-08-19 |
| ES2370680T9 (es) | 2012-02-15 |
| JP5236001B2 (ja) | 2013-07-17 |
| EP2200980A1 (en) | 2010-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0309167A (pt) | Composto, processo para a produção de um composto, composição farmacêutica, uso do composto, método para o tratamento de um sujeito afetado por uma condição patológica ou doença e produto de combinação | |
| BRPI0409109A (pt) | novos compostos | |
| BR0207526A (pt) | Composto, composição farmacêutica, e, métodos para o tratamento da dor, da enxaqueca, depressão, ansiedade, esquizofrenia, doença de parkinson ou derrame cerebral | |
| EA200971107A1 (ru) | Катехоламиновые производные, полезные для лечения болезни паркинсона | |
| MA32898B1 (fr) | Modulateurs allosteriques positifs du recepteur m1 d'arylmethylbenzoquinazolinone | |
| EA201200002A1 (ru) | Производные индоламида и родственные соединения для использования при лечении нейродегенеративных заболеваний | |
| MX2010004026A (es) | Piperidino-dihidrotienopirimidinas sustituidas. | |
| SE0301009D0 (sv) | Novel compounds | |
| PT1716152E (pt) | Compostos heterocíclicos fundidos e sua utilização como antagonistas do receptor metabotrópico para o tratamento de distúrbios gastrointestinais | |
| BRPI0417376A (pt) | compostos, processo para a manufatura dos mesmos, composições farmacêuticas que os compreendem, método para o tratamento e/ou profilaxia de enfermidades que estão associadas com a modulação de receptores de cb1 e sua utilização | |
| MY147677A (en) | Piperazinyl derivatives useful in the treatment of gpr38 receptor mediated diseases | |
| WO2009025785A3 (en) | Cb2 receptor ligands for the treatment of pain | |
| UA84048C2 (ru) | Производные сульфонамида для лечения заболеваний, способ их получения (варианты), фармацевтическая композиция на их основе | |
| EP1784388B8 (en) | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | |
| BR112012003464B8 (pt) | compostos de piranil aril metil benzoquinaozlinona, uso dos mesmos, e, composição farmacêutica | |
| BRPI0508051A (pt) | derivados de heteroarilaminopirazol utilizáveis para o tratamento de diabetes | |
| TW200630336A (en) | Novel compounds | |
| DE502005010170D1 (de) | Neue langwirksame beta-2-agonisten, und deren verwendung als arzneimittel | |
| BRPI0510501A (pt) | antagonistas do receptor 3 de histamina | |
| BRPI0816571A2 (pt) | "composto, processo para preparação do composto, composição farmacêutica, agente e método para o tratamento de uma doença ou uma desordem do sistema nervoso central relacionada à ou afetada pelo recptor 5-ht6" | |
| BRPI0507120A (pt) | compostos, processo para a manufatura dos mesmos, composições farmacêuticas que os compreendem, método para o tratamento e/ou profilaxia de enfermidades que estão associadas com a modulação de receptores de cb1 e sua utilização | |
| BRPI0809873A2 (pt) | "composto, processo para a preparação do composto, método para o tratamento de uma desordem do sistema nervoso central, composição farmacêutica, uso do composto, método para testar antagonistas e antagonistas com seletividade para o receptor 5-th6 e método de tratamento" | |
| BRPI0509515A (pt) | composto, formulação farmacêutica, uso de um composto método para tratamento de doenças, e, processo para a preparação de um composto | |
| EA200801302A1 (ru) | Композиции и способы лечения нарушений цнс | |
| WO2009117283A3 (en) | Quinolizidinone m1 receptor positive allosteric modulators |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |