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BRPI0815602A2 - PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM - Google Patents

PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM

Info

Publication number
BRPI0815602A2
BRPI0815602A2 BRPI0815602-6A2A BRPI0815602A BRPI0815602A2 BR PI0815602 A2 BRPI0815602 A2 BR PI0815602A2 BR PI0815602 A BRPI0815602 A BR PI0815602A BR PI0815602 A2 BRPI0815602 A2 BR PI0815602A2
Authority
BR
Brazil
Prior art keywords
trimethyzidine
preparing
proposed
release compositions
compositions
Prior art date
Application number
BRPI0815602-6A2A
Other languages
Portuguese (pt)
Inventor
Deepak Anant Hedge
Sandhya Rajendra Shenoy
Harish Tulsidutt Bhatt
Ashok Omray
Original Assignee
Usv Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Ltd filed Critical Usv Ltd
Publication of BRPI0815602A2 publication Critical patent/BRPI0815602A2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0815602-6A2A 2007-08-08 2008-08-07 PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM BRPI0815602A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1533MU2007 2007-08-08
PCT/IN2008/000493 WO2009066315A2 (en) 2007-08-08 2008-08-07 Sustained release compositions of trimetazidine and process for preparation thereof

Publications (1)

Publication Number Publication Date
BRPI0815602A2 true BRPI0815602A2 (en) 2015-03-03

Family

ID=40667940

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815602-6A2A BRPI0815602A2 (en) 2007-08-08 2008-08-07 PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM

Country Status (3)

Country Link
EP (1) EP2187874A2 (en)
BR (1) BRPI0815602A2 (en)
WO (1) WO2009066315A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010084397A2 (en) * 2009-01-20 2010-07-29 Micro Labs Limited Modified release solid pharmaceutical compositions of trimetazidine and process thereof
TR201001902A2 (en) * 2010-03-12 2011-04-21 Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. Trimetazidine tablets with extended release
EP2394644B1 (en) * 2010-05-04 2014-07-09 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Trimetazidine Formulation With Different Release Profiles
EP2386302A1 (en) * 2010-05-11 2011-11-16 Ranbaxy Laboratories Limited A controlled release pharmaceutical dosage form of trimetazidine and processes for the preparation thereof
WO2013180676A1 (en) * 2012-05-28 2013-12-05 Mahmut Bilgic A new sustained release formulation
CN105434380A (en) * 2015-12-11 2016-03-30 南京正科医药股份有限公司 Trimetazidine dihydrochloride tablet
US11123345B2 (en) 2016-11-21 2021-09-21 Saghmos Therapeutics, Inc. Prevention and/or treatment of contrast-induced acute kidney injury
US10556013B2 (en) 2017-06-20 2020-02-11 Imbria Pharmaceuticals, Inc. Compositions and methods for increasing efficiency of cardiac metabolism
EP4497474A3 (en) 2018-10-17 2025-04-23 Imbria Pharmaceuticals, Inc. Methods of treating rheumatic diseases using trimetazidine-based compounds
CN110623934B (en) * 2019-09-26 2022-05-13 杭州百诚医药科技股份有限公司 Trimetazidine hydrochloride sustained release tablet and preparation method thereof
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
CN111888476A (en) * 2020-08-17 2020-11-06 深圳市道科思医药有限公司 Modified release pharmaceutical composition of trimetazidine dihydrochloride
CN112315942B (en) * 2020-11-04 2022-08-09 南京康川济医药科技有限公司 Trimetazidine hydrochloride sustained release preparation and preparation method thereof
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine
WO2025068837A2 (en) * 2023-09-26 2025-04-03 Zim Laboratories Limited A novel extended release pharmaceutical composition of trimetazidine or salt thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60042972D1 (en) * 2000-10-05 2009-10-29 Usv Ltd Delayed-release drug-containing trimetazidine and method of preparation
FR2818549B1 (en) * 2000-12-26 2003-02-07 Servier Lab SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF TRIMETAZIDINE
FR2885807B1 (en) * 2005-05-18 2008-05-16 Mg Pharma SOLID PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE, AND PREPARATION METHOD

Also Published As

Publication number Publication date
WO2009066315A3 (en) 2009-09-24
WO2009066315A2 (en) 2009-05-28
EP2187874A2 (en) 2010-05-26

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.