BRPI0814811A2 - Composto, agente, método, e composição de diagnóstico, uso de um composto, e, método de formação de imagem - Google Patents
Composto, agente, método, e composição de diagnóstico, uso de um composto, e, método de formação de imagemInfo
- Publication number
- BRPI0814811A2 BRPI0814811A2 BRPI0814811-2A2A BRPI0814811A BRPI0814811A2 BR PI0814811 A2 BRPI0814811 A2 BR PI0814811A2 BR PI0814811 A BRPI0814811 A BR PI0814811A BR PI0814811 A2 BRPI0814811 A2 BR PI0814811A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- agent
- image formation
- diagnostic composition
- formation method
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0452—Solutions, e.g. for injection
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20073594 | 2007-07-12 | ||
| NO20073595 | 2007-07-12 | ||
| PCT/NO2008/000255 WO2009008734A2 (en) | 2007-07-12 | 2008-07-04 | Contrast agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0814811A2 true BRPI0814811A2 (pt) | 2015-02-03 |
Family
ID=39811676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0814811-2A2A BRPI0814811A2 (pt) | 2007-07-12 | 2008-07-04 | Composto, agente, método, e composição de diagnóstico, uso de um composto, e, método de formação de imagem |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8920780B2 (pt) |
| EP (1) | EP2178568B1 (pt) |
| JP (3) | JP5340281B2 (pt) |
| KR (2) | KR20100033405A (pt) |
| CN (4) | CN101687051A (pt) |
| AU (1) | AU2008273037B2 (pt) |
| BR (1) | BRPI0814811A2 (pt) |
| CA (1) | CA2692646C (pt) |
| CO (1) | CO6351754A2 (pt) |
| DK (1) | DK2178568T3 (pt) |
| ES (1) | ES2486296T3 (pt) |
| HR (1) | HRP20140649T1 (pt) |
| IL (1) | IL202487A (pt) |
| NZ (1) | NZ581765A (pt) |
| PL (1) | PL2178568T3 (pt) |
| PT (1) | PT2178568E (pt) |
| RU (1) | RU2469021C2 (pt) |
| WO (1) | WO2009008734A2 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2692646C (en) * | 2007-07-12 | 2014-09-09 | Mikkel Thaning | Contrast agents |
| CN102271715A (zh) * | 2009-01-09 | 2011-12-07 | 通用电气医疗集团股份有限公司 | 对比剂组合物 |
| KR101545045B1 (ko) | 2009-10-29 | 2015-08-17 | 지이 헬스케어 에이에스 | 탁월한 안전성 프로파일을 갖는 혈장 양이온을 포함하는 진단학적 조성물 |
| CN102802671B (zh) * | 2010-03-23 | 2015-07-22 | 通用电气医疗集团股份有限公司 | 稳定的x射线诊断组合物的制备 |
| NZ605674A (en) * | 2010-07-12 | 2014-11-28 | Ge Healthcare As | X-ray imaging at low contrast agent concentrations and/or low dose radiation |
| US9474808B2 (en) | 2010-12-21 | 2016-10-25 | Ge Healthcare As | Desalination of a composition comprising a contrast agent |
| WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
| EP2758319B1 (en) | 2011-09-21 | 2016-06-08 | GE Healthcare AS | Packaging of contrast media |
| GB2496971A (en) * | 2011-11-25 | 2013-05-29 | Ge Healthcare As | Preparation of X-ray contrast agents |
| NO333914B1 (no) * | 2011-12-21 | 2013-10-21 | Ge Healthcare As | Stabilisering av diagnostisk røntgensammensetning |
| NZ626988A (en) * | 2012-01-11 | 2015-10-30 | Ge Healthcare As | X-ray imaging contrast media with low iodine concentration and x-ray imaging process |
| CA2881852A1 (en) | 2012-09-27 | 2014-04-03 | Ge Healthcare As | Preparation of an intermediate compound of ioforminol |
| ES2702275T3 (es) * | 2012-09-27 | 2019-02-28 | Ge Healthcare As | Preparación de ioforminol, un agente de contraste de rayos X |
| PT2917174T (pt) * | 2012-11-12 | 2018-11-14 | Ge Healthcare As | Preparação de intermediários de agentes de contraste de raios-x |
| CN104854080B (zh) | 2012-12-19 | 2018-07-03 | 通用电气医疗集团股份有限公司 | X-射线造影剂的纯化 |
| WO2014158965A1 (en) | 2013-03-27 | 2014-10-02 | Ge Healthcare As | Method and reagent for preparing a diagnostic composition |
| CN105793235B (zh) * | 2013-12-06 | 2019-08-23 | 通用电气医疗集团股份有限公司 | 纯化非离子x射线造影剂合成中的中间体的备选方法 |
| CN105017063B (zh) * | 2014-04-18 | 2018-11-20 | 沈阳中海生物技术开发有限公司 | 5-氨基-2,4,6-三碘间苯二甲酸衍生物及其盐、水合物或溶剂化物 |
| CN108341750B (zh) * | 2017-01-21 | 2020-10-23 | 浙江海洲制药有限公司 | 一种制备碘化造影剂中间体时所产生的杂质的合成方法 |
| CN114560775B (zh) * | 2022-03-17 | 2023-08-22 | 绵阳师范学院 | (r,s)-7-氟-1,1,3-三甲基-2,3-二氢-1h-茚-4-胺的制备方法 |
| US12329831B2 (en) | 2023-04-23 | 2025-06-17 | Translational And Fundamental Technologies Institute Llc | Radionuclide-loaded nanoparticles for focal tissue ablation |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE344166B (pt) | 1966-12-13 | 1972-04-04 | Pharmacia Ab | |
| US3763227A (en) | 1967-12-28 | 1973-10-02 | Pharmacia Ab | Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof |
| US3804892A (en) | 1967-12-28 | 1974-04-16 | Pharmacia Ab | Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof |
| SE315974B (pt) * | 1967-12-28 | 1969-10-13 | Pharmacia Ab | |
| DE2628517C2 (de) | 1976-06-23 | 1985-02-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel |
| IT1207226B (it) | 1979-08-09 | 1989-05-17 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono. |
| DE3038853A1 (de) | 1980-10-10 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii) |
| DK160868C (da) * | 1982-11-08 | 1991-10-14 | Nyegaard & Co As | Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem |
| IL86450A (en) * | 1987-05-22 | 1994-05-30 | Bracco Int Bv | Process for making a history of 5-acylamino-2,4,6-triiodo and tribromo-benzoic acid, and some such new compounds |
| FR2634571B1 (fr) | 1988-07-19 | 1990-10-19 | Kodak Pathe | Procede d'organisation et de lecture d'un support magnetique et support en faisant application |
| IL94718A (en) * | 1989-07-05 | 1994-10-21 | Schering Ag | Non-ionic carboxamide contrast agent and method of preparation |
| GB9020091D0 (en) | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| IT1245853B (it) | 1990-11-16 | 1994-10-25 | Bracco Spa | 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono |
| WO1994014476A1 (en) | 1992-12-21 | 1994-07-07 | The Procter & Gamble Company | Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders |
| IT1256248B (it) | 1992-12-24 | 1995-11-29 | Bracco Spa | Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x |
| GB9303992D0 (en) | 1993-02-26 | 1993-04-14 | Nycomed Imaging As | Contrast agents |
| WO1994022810A1 (es) | 1993-04-01 | 1994-10-13 | Centro Investigacion Justesa Imagen, S.A. | Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen |
| CN1164225A (zh) * | 1994-09-23 | 1997-11-05 | 尼科梅德成像有限公司 | 碘代x-射线造影剂 |
| GB9419203D0 (en) | 1994-09-23 | 1994-11-09 | Nycomed Innovation Ab | Contrast media |
| AU6114396A (en) * | 1995-06-16 | 1997-01-15 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
| US6072069A (en) | 1998-11-04 | 2000-06-06 | Biophysica, Inc. | Biodegradable nonionic contrast media |
| GB9903109D0 (en) | 1999-02-11 | 1999-04-07 | Nycomed Imaging As | Process |
| EP1186305A1 (en) | 2000-09-07 | 2002-03-13 | Schering Aktiengesellschaft | New brominated compounds as contrast media for X-ray mammography |
| US7371877B2 (en) | 2002-03-27 | 2008-05-13 | Fujifilm Corporation | Glycerol ester derivative |
| JP4096908B2 (ja) * | 2004-03-31 | 2008-06-04 | 株式会社豊田自動織機 | 回転電機の製造方法 |
| US20050281746A1 (en) * | 2004-06-16 | 2005-12-22 | Melton Laura J | Anticoagulant contrast media |
| CA2692646C (en) * | 2007-07-12 | 2014-09-09 | Mikkel Thaning | Contrast agents |
| JP6723006B2 (ja) | 2015-12-10 | 2020-07-15 | 株式会社オカムラ | 椅子 |
-
2008
- 2008-07-04 CA CA2692646A patent/CA2692646C/en not_active Expired - Fee Related
- 2008-07-04 US US12/665,792 patent/US8920780B2/en not_active Expired - Fee Related
- 2008-07-04 CN CN200880024347A patent/CN101687051A/zh active Pending
- 2008-07-04 HR HRP20140649AT patent/HRP20140649T1/hr unknown
- 2008-07-04 KR KR1020107000521A patent/KR20100033405A/ko not_active Ceased
- 2008-07-04 PL PL08793873T patent/PL2178568T3/pl unknown
- 2008-07-04 JP JP2010515994A patent/JP5340281B2/ja not_active Expired - Fee Related
- 2008-07-04 NZ NZ581765A patent/NZ581765A/en not_active IP Right Cessation
- 2008-07-04 AU AU2008273037A patent/AU2008273037B2/en not_active Ceased
- 2008-07-04 DK DK08793873.4T patent/DK2178568T3/da active
- 2008-07-04 EP EP08793873.4A patent/EP2178568B1/en not_active Not-in-force
- 2008-07-04 BR BRPI0814811-2A2A patent/BRPI0814811A2/pt not_active Application Discontinuation
- 2008-07-04 PT PT87938734T patent/PT2178568E/pt unknown
- 2008-07-04 RU RU2009148141/04A patent/RU2469021C2/ru not_active IP Right Cessation
- 2008-07-04 ES ES08793873.4T patent/ES2486296T3/es active Active
- 2008-07-04 KR KR1020147024003A patent/KR101555457B1/ko not_active Expired - Fee Related
- 2008-07-04 CN CN201410177453.1A patent/CN103951585A/zh active Pending
- 2008-07-04 CN CN201410177572.7A patent/CN103951586B/zh not_active Expired - Fee Related
- 2008-07-04 CN CN201410177332.7A patent/CN103980154B/zh not_active Expired - Fee Related
- 2008-07-04 WO PCT/NO2008/000255 patent/WO2009008734A2/en not_active Ceased
-
2009
- 2009-12-03 IL IL202487A patent/IL202487A/en active IP Right Grant
- 2009-12-29 CO CO09148547A patent/CO6351754A2/es active IP Right Grant
-
2013
- 2013-03-19 JP JP2013056039A patent/JP5628363B2/ja not_active Expired - Fee Related
-
2014
- 2014-08-12 JP JP2014164199A patent/JP5830589B2/ja not_active Expired - Fee Related
- 2014-12-12 US US14/568,513 patent/US9738596B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
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