BRPI0716635A8 - sistema de detecção e quantificação de matéria biológica constituído por um ou mais sensores óticos e uma ou mais fontes luminosas, processo associado e respectivas utilizações - Google Patents
sistema de detecção e quantificação de matéria biológica constituído por um ou mais sensores óticos e uma ou mais fontes luminosas, processo associado e respectivas utilizaçõesInfo
- Publication number
- BRPI0716635A8 BRPI0716635A8 BRPI0716635A BRPI0716635A BRPI0716635A8 BR PI0716635 A8 BRPI0716635 A8 BR PI0716635A8 BR PI0716635 A BRPI0716635 A BR PI0716635A BR PI0716635 A BRPI0716635 A BR PI0716635A BR PI0716635 A8 BRPI0716635 A8 BR PI0716635A8
- Authority
- BR
- Brazil
- Prior art keywords
- amorphous
- biological
- light sources
- detection
- functionalized
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 230000003287 optical effect Effects 0.000 title abstract 2
- 238000011002 quantification Methods 0.000 title abstract 2
- 239000002131 composite material Substances 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 229910052751 metal Inorganic materials 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108091005461 Nucleic proteins Proteins 0.000 abstract 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 229910045601 alloy Inorganic materials 0.000 abstract 1
- 239000000956 alloy Substances 0.000 abstract 1
- 229910021417 amorphous silicon Inorganic materials 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000012620 biological material Substances 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000000919 ceramic Substances 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 1
- 239000010931 gold Substances 0.000 abstract 1
- 229910052737 gold Inorganic materials 0.000 abstract 1
- 229910021424 microcrystalline silicon Inorganic materials 0.000 abstract 1
- 229910021423 nanocrystalline silicon Inorganic materials 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 239000004065 semiconductor Substances 0.000 abstract 1
- 239000010409 thin film Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
sistema de deteção e quantificação de matéria biológica constituído por um ou mais sensores óticos e uma ou mais fontes luminosas, processo associado e aplicações relacionadas a invenção atual relaciona- se a um sistema e a um processo para a deteção e/ou a identificação qualitativa e quantitativa do material biológico, tal como seqüências específicas de ácidos nucleicos ou de proteínas como anticorpos, presente em amostras biológicas. o sistema é composto por uma ou mais fontes luminosas ( 1) combinadas com um ou mais fotosensores óticos integrados, ou não, e vários componentes eletrônicos ( 4) , necessários para obter/processar o sinal emitido pelas nanosondas de metal funcionalizadas com uma solução de compósi to biológico, assim como igualmente um microcontrolador e um microprocessador, reparados ou portátil. esta estrutura do fotosensor pode detectar e determinar as variações da cor produzidas por nanosondas do metal, sendo este preferencialmente ouro, funcionalizado pelos oligonucleotídeos complementares às seqüências específicas, as proteínas de dna/rna, como por exemplo os anticorpos e/ou os antígenos relativos a determinada doença, ou a outra amostra ou solução de composto biológico, que devem ser investigada. a deteção e o processo da quantificação são baseados na resposta de um fotosensor, singular ou integrados, baseado na tecnologia da película fina de silicones amorfos, nanocristalinos ou microcristalino e suas ligas, assim como os semicondutores cerâmicos ativos novos, amorfos e não amorfos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT103561A PT103561A (pt) | 2006-09-08 | 2006-09-08 | Sistema de detecção e quantificação de matéria biológica constituído por um ou mais sensores ópticos e uma ou mais fontes luminosas, processo associado e respectivas utilizações |
| PT103561 | 2006-09-08 | ||
| PCT/IB2007/053614 WO2008029374A2 (en) | 2006-09-08 | 2007-09-07 | Detection and quantification system of biological matter constituted by one or more optical sensors and one or more light sources, associated process and related applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0716635A2 BRPI0716635A2 (pt) | 2013-10-15 |
| BRPI0716635A8 true BRPI0716635A8 (pt) | 2019-02-05 |
Family
ID=39096108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0716635A BRPI0716635A8 (pt) | 2006-09-08 | 2007-09-07 | sistema de detecção e quantificação de matéria biológica constituído por um ou mais sensores óticos e uma ou mais fontes luminosas, processo associado e respectivas utilizações |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8377699B2 (pt) |
| EP (1) | EP2059810B1 (pt) |
| AT (1) | ATE505729T1 (pt) |
| BR (1) | BRPI0716635A8 (pt) |
| DE (1) | DE602007013915D1 (pt) |
| ES (1) | ES2365079T3 (pt) |
| PT (2) | PT103561A (pt) |
| WO (1) | WO2008029374A2 (pt) |
| ZA (1) | ZA200901612B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010115147A2 (en) * | 2009-04-02 | 2010-10-07 | Life Technologies Corporation | Biomolecular sensing with metal-nanostructures |
| US9023607B2 (en) * | 2010-04-26 | 2015-05-05 | Intellectual Discovery Co., Ltd. | Method for early diagnosis of alzheimer'S disease using phototransistor |
| CN102033125B (zh) * | 2010-10-29 | 2013-08-14 | 济南大学 | 基于免疫纳米晶的现场快速体外即时多疾病同时诊断石英荧光传感器的研究与应用 |
| US8416418B2 (en) | 2011-07-14 | 2013-04-09 | Kendall Technology Inc. | Method and apparatus for gold detection |
| US9188531B2 (en) | 2011-07-14 | 2015-11-17 | Kendall Technology Inc. | Method and apparatus for gold detection |
| RU2474443C1 (ru) * | 2011-11-28 | 2013-02-10 | Борис Николаевич Хлебцов | Термосенсибилизатор для лазерной гипертермии и способ его получения |
| US9310352B2 (en) | 2012-12-14 | 2016-04-12 | The Board Of Trustees Of The Leland Stanford Junior University | Biological cell nanocavity probes |
| WO2017160399A1 (en) * | 2016-03-15 | 2017-09-21 | Byunghoo Jung | Devices, systems, and methods for detecting targeted compounds |
| US11559216B1 (en) * | 2016-08-12 | 2023-01-24 | Apple Inc. | Integrated photodiode |
| CN109298804B (zh) * | 2018-10-23 | 2022-10-28 | 京东方科技集团股份有限公司 | 触控电路及其驱动方法、触控基板及显示装置 |
| KR102165771B1 (ko) * | 2018-10-23 | 2020-10-14 | 광주과학기술원 | 자가발전 바이오 센서, 상기 바이오 센서의 제조 방법 및 상기 바이오 센서를 포함하는 스마트 바이오 센서 시스템 |
| WO2020167486A1 (en) * | 2019-02-12 | 2020-08-20 | Becton, Dickinson And Company | Cap for disinfection of a medical device |
| US12263256B2 (en) * | 2019-02-12 | 2025-04-01 | Becton, Dickinson And Company | Medical device to disinfect a skin surface |
| CN114324537B (zh) * | 2021-12-13 | 2023-03-21 | 中国科学院上海微系统与信息技术研究所 | 一种光电集成生物传感器及生物分子检测设备 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2598435A1 (fr) | 1986-05-06 | 1987-11-13 | Clonatec Sa | Procede et dispositif pour la detection de genomes viraux a adn et arn dans les milieux biologiques, notamment dans le serum sanguin |
| GR1004178B (el) * | 2001-11-29 | 2003-03-05 | "����������" | Ολοκληρωμενος οπτοηλεκτρονικος βιοαισθητηρας πυριτιου για ανιχνευση βιομοριων επισημασμενων με χρωμοφορες ομαδες ή νανοσωματιδια |
| WO2004029566A1 (en) * | 2002-09-26 | 2004-04-08 | Bio Techplex Corporation | Method and apparatus for screening using a waveform modulated led |
| US7221455B2 (en) * | 2004-01-20 | 2007-05-22 | The Regents Of The Unversity Of California | Integrated, fluorescence-detecting microanalytical system |
| US7173702B2 (en) | 2004-07-15 | 2007-02-06 | Lockheed Martin Corporation | Sensor comprising multi-wavelength LEDs |
| US20060127931A1 (en) * | 2004-11-15 | 2006-06-15 | Bradley Schmidt | Particle detector with waveguide light confinement |
| CN100395349C (zh) | 2004-12-22 | 2008-06-18 | 华南师范大学 | 等位特异性扩增与纳米金探针结合的基因点突变检测方法 |
-
2006
- 2006-09-08 PT PT103561A patent/PT103561A/pt not_active Application Discontinuation
-
2007
- 2007-09-07 AT AT07826303T patent/ATE505729T1/de not_active IP Right Cessation
- 2007-09-07 US US12/440,297 patent/US8377699B2/en active Active
- 2007-09-07 WO PCT/IB2007/053614 patent/WO2008029374A2/en not_active Ceased
- 2007-09-07 EP EP07826303A patent/EP2059810B1/en active Active
- 2007-09-07 DE DE602007013915T patent/DE602007013915D1/de active Active
- 2007-09-07 BR BRPI0716635A patent/BRPI0716635A8/pt not_active Application Discontinuation
- 2007-09-07 ES ES07826303T patent/ES2365079T3/es active Active
- 2007-09-07 PT PT07826303T patent/PT2059810E/pt unknown
-
2009
- 2009-03-06 ZA ZA200901612A patent/ZA200901612B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0716635A2 (pt) | 2013-10-15 |
| EP2059810A2 (en) | 2009-05-20 |
| ZA200901612B (en) | 2009-12-30 |
| PT103561A (pt) | 2008-03-31 |
| EP2059810B1 (en) | 2011-04-13 |
| WO2008029374A2 (en) | 2008-03-13 |
| PT2059810E (pt) | 2011-07-19 |
| WO2008029374A3 (en) | 2008-08-21 |
| ES2365079T3 (es) | 2011-09-21 |
| DE602007013915D1 (de) | 2011-05-26 |
| ATE505729T1 (de) | 2011-04-15 |
| US8377699B2 (en) | 2013-02-19 |
| US20100041161A1 (en) | 2010-02-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |