BRPI0600275A - prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricação - Google Patents
prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricaçãoInfo
- Publication number
- BRPI0600275A BRPI0600275A BRPI0600275-7A BRPI0600275A BRPI0600275A BR PI0600275 A BRPI0600275 A BR PI0600275A BR PI0600275 A BRPI0600275 A BR PI0600275A BR PI0600275 A BRPI0600275 A BR PI0600275A
- Authority
- BR
- Brazil
- Prior art keywords
- restenosis
- prevention
- treatment
- manufacturing process
- drug composition
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 3
- 208000037803 restenosis Diseases 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 abstract 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 abstract 2
- 229960002930 sirolimus Drugs 0.000 abstract 2
- 229930012538 Paclitaxel Natural products 0.000 abstract 1
- 229960001592 paclitaxel Drugs 0.000 abstract 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
PRóTESE CORONáRIA LIBERADORA DE COMPOSIçãO MEDICAMENTOSA PARA PREVENçãO E TRATAMENTO DA REESTENOSE E PROCESSO DE FABRICAçãO. é descrita uma prótese coronária liberadora de composição medicamentosa para a prevenção e tratamento da reestenose e processo de fabricação que compreende entre 10,0 a 500,0 Ug/cm¬ 2¬ da superfície da prótese coronária revestida com rapamicina (sirolimus) ou análogos e entre 0,01 a 20,0 Ug/mm¬ 2¬ da superfície da prótese coronária revestida com paclitaxel ou análogos.
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0600275-7A BRPI0600275A (pt) | 2006-01-03 | 2006-01-03 | prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricação |
| AU2007203734A AU2007203734A1 (en) | 2006-01-03 | 2007-01-03 | Coronary stent that releases medicamentuous composition to prevent and treat restenosis and fabrication process |
| JP2008547811A JP2009521961A (ja) | 2006-01-03 | 2007-01-03 | 再狭窄予防治療のために薬物組成を放出する冠状動脈ステントとその組み立て工程 |
| EP07700097.4A EP1986714A4 (en) | 2006-01-03 | 2007-01-03 | CORONARY STENT THAT RELEASES A DRUG COMPOSITION FOR PREVENTING AND TREATING RESTENOSIS AND METHOD OF MANUFACTURING |
| PCT/BR2007/000004 WO2007076588A1 (en) | 2006-01-03 | 2007-01-03 | Coronary stent that releases medicamentuous composition to prevent and treat restenosis and fabrication process |
| CNA2007800017509A CN101370533A (zh) | 2006-01-03 | 2007-01-03 | 释放药物组合物以防止和治疗再狭窄的冠状动脉支架和制造方法 |
| CA002636299A CA2636299A1 (en) | 2006-01-03 | 2007-01-03 | Coronary artery stent releasing a drug composition for prevention and treatment of restenosis |
| US12/215,936 US20090012605A1 (en) | 2006-01-03 | 2008-07-01 | Coronary stent that releases medicamentuous composition to prevent and treat restenosis and fabrication process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0600275-7A BRPI0600275A (pt) | 2006-01-03 | 2006-01-03 | prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricação |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0600275A true BRPI0600275A (pt) | 2007-10-02 |
Family
ID=38227860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0600275-7A BRPI0600275A (pt) | 2006-01-03 | 2006-01-03 | prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricação |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090012605A1 (pt) |
| EP (1) | EP1986714A4 (pt) |
| JP (1) | JP2009521961A (pt) |
| CN (1) | CN101370533A (pt) |
| AU (1) | AU2007203734A1 (pt) |
| BR (1) | BRPI0600275A (pt) |
| CA (1) | CA2636299A1 (pt) |
| WO (1) | WO2007076588A1 (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8057816B2 (en) | 1997-09-26 | 2011-11-15 | Abbott Laboratories | Compositions and methods of administering paclitaxel with other drugs using medical devices |
| US8257726B2 (en) | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices |
| US7637940B2 (en) * | 2007-07-06 | 2009-12-29 | Boston Scientific Scimed, Inc. | Stent with bioabsorbable membrane |
| WO2011086574A2 (en) * | 2010-01-18 | 2011-07-21 | Concept Medical Research Private Limited | Formulations of nano-carriers and methods of preparing the same |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050163818A1 (en) * | 1996-11-05 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting device chemically treated with genipin |
| US6273913B1 (en) * | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| US20030129215A1 (en) * | 1998-09-24 | 2003-07-10 | T-Ram, Inc. | Medical devices containing rapamycin analogs |
| US8029561B1 (en) * | 2000-05-12 | 2011-10-04 | Cordis Corporation | Drug combination useful for prevention of restenosis |
| US7807211B2 (en) * | 1999-09-03 | 2010-10-05 | Advanced Cardiovascular Systems, Inc. | Thermal treatment of an implantable medical device |
| EP2314293B1 (en) * | 2001-01-16 | 2017-01-04 | Vascular Therapies, LLC | Implantable device containing resorbable matrix material and rapamycin for preventing or treating vasuloproliferative diseases |
| US7771468B2 (en) * | 2001-03-16 | 2010-08-10 | Angiotech Biocoatings Corp. | Medicated stent having multi-layer polymer coating |
| US20030065382A1 (en) * | 2001-10-02 | 2003-04-03 | Fischell Robert E. | Means and method for the treatment of coronary artery obstructions |
| AU2003228858A1 (en) * | 2002-05-02 | 2003-11-17 | Scimed Life Systems, Inc. | Energetically-controlled delivery of biologically active material from an implanted medical device |
| US20050163821A1 (en) * | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
| EP1572029B1 (en) * | 2002-11-07 | 2010-03-24 | Abbott Laboratories | Method of loading beneficial agent to a prosthesis by fluid-jet application |
| US20050064005A1 (en) * | 2003-08-13 | 2005-03-24 | Dinh Thomas Q. | Active agent delivery systems including a miscible polymer blend, medical devices, and methods |
| ITTO20040056A1 (it) * | 2004-02-05 | 2004-05-05 | Sorin Biomedica Cardio Spa | Stent per l'erogazione endoliminale di principi o agenti attivi |
| KR100891148B1 (ko) * | 2004-02-28 | 2009-04-06 | 헤모텍 아게 | 의료용 표면의 생체적합성 코팅, 방법 및 그 용도 |
| JP4949227B2 (ja) * | 2004-03-19 | 2012-06-06 | アボット・ラボラトリーズ | バルーンおよびプロテーゼからの多剤送達 |
| US20050288481A1 (en) * | 2004-04-30 | 2005-12-29 | Desnoyer Jessica R | Design of poly(ester amides) for the control of agent-release from polymeric compositions |
-
2006
- 2006-01-03 BR BRPI0600275-7A patent/BRPI0600275A/pt not_active IP Right Cessation
-
2007
- 2007-01-03 CA CA002636299A patent/CA2636299A1/en not_active Abandoned
- 2007-01-03 AU AU2007203734A patent/AU2007203734A1/en not_active Abandoned
- 2007-01-03 JP JP2008547811A patent/JP2009521961A/ja active Pending
- 2007-01-03 CN CNA2007800017509A patent/CN101370533A/zh active Pending
- 2007-01-03 EP EP07700097.4A patent/EP1986714A4/en not_active Withdrawn
- 2007-01-03 WO PCT/BR2007/000004 patent/WO2007076588A1/en not_active Ceased
-
2008
- 2008-07-01 US US12/215,936 patent/US20090012605A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2636299A1 (en) | 2007-07-12 |
| EP1986714A1 (en) | 2008-11-05 |
| AU2007203734A1 (en) | 2007-07-12 |
| WO2007076588A1 (en) | 2007-07-12 |
| EP1986714A4 (en) | 2014-01-22 |
| US20090012605A1 (en) | 2009-01-08 |
| JP2009521961A (ja) | 2009-06-11 |
| CN101370533A (zh) | 2009-02-18 |
| WO2007076588B1 (en) | 2007-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 13A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2495 DE 30-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |