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BRPI0511390A - tiazolinona quinolinas não-substituìdas - Google Patents

tiazolinona quinolinas não-substituìdas

Info

Publication number
BRPI0511390A
BRPI0511390A BRPI0511390-3A BRPI0511390A BRPI0511390A BR PI0511390 A BRPI0511390 A BR PI0511390A BR PI0511390 A BRPI0511390 A BR PI0511390A BR PI0511390 A BRPI0511390 A BR PI0511390A
Authority
BR
Brazil
Prior art keywords
thiazolinone
quinolines
unsubstituted
compounds
quinoline
Prior art date
Application number
BRPI0511390-3A
Other languages
English (en)
Inventor
Shaoqing Chen
Li Chen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35262226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0511390(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0511390A publication Critical patent/BRPI0511390A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

TIAZOLINONA QUINOLINAS NãO-SUBSTITUìDAS. A presente invenção refere-se a derivados de tiazolinona quinolina da fórmula (I) não tendo nenhuma substituição no anel quinolina e sendo ativos como inibidores de CDK1; a processos para a fabricação dos ditos compostos bem como o uso dos ditos compostos para a produção de medicamentos.
BRPI0511390-3A 2004-07-01 2005-06-23 tiazolinona quinolinas não-substituìdas BRPI0511390A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58474604P 2004-07-01 2004-07-01
US62949504P 2004-11-19 2004-11-19
PCT/EP2005/006807 WO2006002829A1 (en) 2004-07-01 2005-06-23 Thiazolinone unsubstituted quinolines

Publications (1)

Publication Number Publication Date
BRPI0511390A true BRPI0511390A (pt) 2007-12-04

Family

ID=35262226

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511390-3A BRPI0511390A (pt) 2004-07-01 2005-06-23 tiazolinona quinolinas não-substituìdas

Country Status (15)

Country Link
US (1) US7326786B2 (pt)
EP (1) EP1765817A1 (pt)
JP (1) JP2008504324A (pt)
KR (1) KR100866298B1 (pt)
CN (1) CN1984909A (pt)
AR (1) AR050165A1 (pt)
AU (1) AU2005259512A1 (pt)
BR (1) BRPI0511390A (pt)
CA (1) CA2571738A1 (pt)
IL (1) IL180313A0 (pt)
MX (1) MXPA06015028A (pt)
NO (1) NO20070564L (pt)
RU (1) RU2007103709A (pt)
TW (1) TW200612942A (pt)
WO (1) WO2006002829A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR053602A1 (es) * 2005-05-03 2007-05-09 Smithkline Beecham Corp Compuesto de 2- arilamino -4-oxo-1,3-tiazol-5(4h)- substituido, composicion farmaceutica que lo comprende, proceso para prepararla y uso del compuesto para preparar un medicamento
EP1885362A4 (en) * 2005-05-23 2010-09-22 Glaxosmithkline Llc NEW CHEMICAL COMPOUNDS
PE20070083A1 (es) * 2005-06-08 2007-01-27 Smithkline Beecham Corp (5z)-5-(6-quinoxalinilmetilideno)-2-[(2,6-diclorofenil)amino]-1,3-tiazol-4(5h)-ona
KR20080034436A (ko) * 2005-07-21 2008-04-21 베타게논 에이비 암 치료에 사용되는 티아졸 유도체 및 유사체
TW200745066A (en) 2005-09-16 2007-12-16 Torrent Pharmaceuticals Ltd Novel PTP1B inhibitors
EP1993538A4 (en) * 2006-03-02 2010-05-19 Glaxosmithkline Llc THIAZOLONES AS INHIBITORS OF P13-KINASES
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
WO2010086613A1 (en) 2009-01-30 2010-08-05 Betagenon Ab Compounds useful as inhibitors as ampk
JP5679855B2 (ja) * 2011-02-14 2015-03-04 国立大学法人群馬大学 ジフルオロメチル化ヘテロアリール化合物の製造方法
CN104016942B (zh) * 2014-06-16 2016-02-24 天津医科大学 噻唑啉酮类衍生物及其药物组合物与应用
CN106831451B (zh) * 2017-02-03 2018-09-21 荆楚理工学院 一种2-氨基异丁醇的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1215208B1 (en) * 1997-10-27 2006-07-12 Agouron Pharmaceuticals, Inc. 4-Aminothiazole derivatives, their preparation and their use as inhibitors of cyclin-dependent kinases
EP1087951B9 (en) * 1998-06-18 2006-09-13 Bristol-Myers Squibb Company Carbon substituted aminothiazole inhibitors of cyclin dependent kinases
ES2315566T3 (es) * 2002-11-22 2009-04-01 Smithkline Beecham Corporation Tiazolidin-4-onas para inhibir proteinas hyak3.
WO2005011686A1 (en) * 2003-07-28 2005-02-10 Applied Research Systems Ars Holding N.V. 2-imino-4-(thio) oxo-5-poly cyclovinylazolines for use as p13 kinase ihibitors

Also Published As

Publication number Publication date
US20060004045A1 (en) 2006-01-05
WO2006002829A1 (en) 2006-01-12
AU2005259512A1 (en) 2006-01-12
KR100866298B1 (ko) 2008-10-31
TW200612942A (en) 2006-05-01
MXPA06015028A (es) 2007-02-08
CN1984909A (zh) 2007-06-20
EP1765817A1 (en) 2007-03-28
US7326786B2 (en) 2008-02-05
RU2007103709A (ru) 2008-08-10
NO20070564L (no) 2007-03-15
JP2008504324A (ja) 2008-02-14
IL180313A0 (en) 2007-06-03
AR050165A1 (es) 2006-10-04
CA2571738A1 (en) 2006-01-12
KR20070024679A (ko) 2007-03-02

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.