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BRPI0511305A - method of relieving an annular or sarcoid granuloma, manufactured article and use of an lfa-1 antagonist - Google Patents

method of relieving an annular or sarcoid granuloma, manufactured article and use of an lfa-1 antagonist

Info

Publication number
BRPI0511305A
BRPI0511305A BRPI0511305-9A BRPI0511305A BRPI0511305A BR PI0511305 A BRPI0511305 A BR PI0511305A BR PI0511305 A BRPI0511305 A BR PI0511305A BR PI0511305 A BRPI0511305 A BR PI0511305A
Authority
BR
Brazil
Prior art keywords
lfa
antagonist
annular
relieving
manufactured article
Prior art date
Application number
BRPI0511305-9A
Other languages
Portuguese (pt)
Inventor
Bernard S Goffe
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BRPI0511305A publication Critical patent/BRPI0511305A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

MéTODO DE ALIVIAR UM GRANULOMA ANULAR OU SARCóIDE, ARTIGO MANUFATURADO E USO DE UM ANTAGONISTA DE LFA-1. A presente invenção refere-se a um método de aliviar o granuloma anular ou doença sarcóide administrando a um paciente que tem a doença, uma quantidade terapeuticamente eficaz de um antagonista de LFA 1.METHOD OF RELIEFING AN ANNULAR OR SARCOID GRANULOMA, MANUFACTURED ARTICLE AND USE OF AN LFA-1 ANTAGONIST. The present invention relates to a method of alleviating annular granuloma or sarcoid disease by administering to a patient having the disease a therapeutically effective amount of an LFA 1 antagonist.

BRPI0511305-9A 2004-06-09 2005-06-08 method of relieving an annular or sarcoid granuloma, manufactured article and use of an lfa-1 antagonist BRPI0511305A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57876804P 2004-06-09 2004-06-09
US57909604P 2004-06-10 2004-06-10
PCT/US2005/020342 WO2005123777A2 (en) 2004-06-09 2005-06-08 Method of treating granuloma annulare or sarcoid

Publications (1)

Publication Number Publication Date
BRPI0511305A true BRPI0511305A (en) 2007-12-04

Family

ID=35355731

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511305-9A BRPI0511305A (en) 2004-06-09 2005-06-08 method of relieving an annular or sarcoid granuloma, manufactured article and use of an lfa-1 antagonist

Country Status (11)

Country Link
US (1) US7396530B2 (en)
EP (1) EP1756163A2 (en)
JP (1) JP2008507592A (en)
AU (1) AU2005254980A1 (en)
BR (1) BRPI0511305A (en)
CA (1) CA2568570A1 (en)
IL (1) IL179557A0 (en)
MX (1) MXPA06014354A (en)
NO (1) NO20070127L (en)
RU (1) RU2006146939A (en)
WO (1) WO2005123777A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1682537T3 (en) 2003-11-05 2012-07-09 Sarcode Bioscience Inc Cell adhesion modulators
EP3167886B1 (en) 2007-10-19 2020-08-05 Novartis AG Compositions and methods for treatment of macular edema
EP2265125B1 (en) * 2008-04-15 2019-08-14 SARcode Bioscience Inc. Topical lfa-1 antagonists for use in localized treatment of immune related disorders
EP3838923B1 (en) 2012-08-24 2024-05-01 The Regents of The University of California Antibodies and vaccines for use in treating ror1 cancers and inhibiting metastasis
WO2018005519A2 (en) 2016-06-27 2018-01-04 The Regents Of The University Of California Cancer treatment combinations
RU2671516C1 (en) * 2018-01-10 2018-11-01 Федеральное государственное бюджетное военное образовательное учреждение высшего образования Военно-медицинская академия имени С.М. Кирова Министерства обороны Российской Федерации (ВМедА) Method of treatment of ring-shaped granuloma

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002869A (en) * 1987-11-02 1991-03-26 Dana-Farber Cancer Institute Monoclonal antibody specific to a novel epitope of the LFA-1 antigen of human T lymphocytes
US5071964A (en) * 1988-05-04 1991-12-10 Dana-Farber Cancer Institute, Inc. Protein micelles
US5147637A (en) 1988-06-07 1992-09-15 The Rockefeller University Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma
NO900155L (en) 1989-01-24 1990-07-25 Molecular Therapeutics Inc A RELIABLE MOLECULE RELATED TO BUT DIFFERENT FROM ICAM-1.
CA2008368C (en) 1989-01-24 2003-04-08 Jeffrey Greve Soluble molecule related to but distinct from icam-1
CA2050329A1 (en) 1989-03-09 1990-09-10 Timothy A. Springer Method of treating viral infections using lfa-1
ATE146222T1 (en) 1989-03-09 1996-12-15 Blood Res Center INTERCELLULAR ADHESION MOLECULE-2 AND ITS BINDING LIGANDS
ZA903258B (en) 1989-04-28 1991-02-27 Baylor College Medicine Method of suppressing hiv infection
DK0432249T3 (en) 1989-06-02 1997-02-17 Univ Johns Hopkins Med Monoclonal antibodies to the beta chain of the leukocyte adhesion receptor, methods for producing these antibodies and their use
US5324510A (en) * 1989-09-01 1994-06-28 Boehringer Ingelheim Pharmaceuticals, Inc. Use of antibodies to intercellular adhesion molecule-1 (ICAM-1) in the treatment of asthma
GB9009549D0 (en) 1990-04-27 1990-06-20 Celltech Ltd Recombinant antibody and method
GB9009548D0 (en) 1990-04-27 1990-06-20 Celltech Ltd Chimeric antibody and method
WO1991018011A1 (en) 1990-05-15 1991-11-28 Swinburne Limited Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
GB9115364D0 (en) * 1991-07-16 1991-08-28 Wellcome Found Antibody
WO1993006864A1 (en) 1991-10-01 1993-04-15 The General Hospital Corporation Preventing allograft rejection with antibodies to adhesion molecules
EP0610290B1 (en) * 1991-10-04 1999-05-26 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Manufacture of a medicament for treatment of ocular inflammation by blockage of cell adhesion molecules
US5932448A (en) * 1991-11-29 1999-08-03 Protein Design Labs., Inc. Bispecific antibody heterodimers
GB2266664A (en) 1992-04-28 1993-11-10 Pierre Francois Piguet Monoclonal antibodies for prophylaxis and treatment of pulmonary fibrosis
AU687755B2 (en) * 1992-08-21 1998-03-05 Genentech Inc. Method for treating an LFA-1-mediated disorder
DK0941344T3 (en) * 1996-11-27 2004-09-27 Genentech Inc Humanized anti-CD11a antibodies
US6037454A (en) * 1996-11-27 2000-03-14 Genentech, Inc. Humanized anti-CD11a antibodies
FR2763072B1 (en) 1997-05-12 1999-11-05 Pasteur Merieux Serums Vacc USE OF A MONOCLONAL ANTI-LFA1 ANTIBODY IN RENAL TRANSPLANTATION
CO5140104A1 (en) * 1999-02-16 2002-03-22 Novartis Ag MEVINOLINE DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING THEM
PE20020420A1 (en) * 2000-10-02 2002-06-27 Novartis Ag DERIVATIVES OF DIAZACICLOALKANODIONA AS ANTAGONISTS OF ANTIGEN ASSOCIATED WITH LYMPHOCYTE-1 FUNCTION (LFA-1)

Also Published As

Publication number Publication date
WO2005123777A3 (en) 2006-03-02
AU2005254980A1 (en) 2005-12-29
US7396530B2 (en) 2008-07-08
RU2006146939A (en) 2008-07-20
IL179557A0 (en) 2007-05-15
US20060013818A1 (en) 2006-01-19
EP1756163A2 (en) 2007-02-28
CA2568570A1 (en) 2005-12-29
WO2005123777A2 (en) 2005-12-29
NO20070127L (en) 2007-01-08
MXPA06014354A (en) 2007-02-19
JP2008507592A (en) 2008-03-13

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.