BRPI0517684A - soluções de retinóide e formulações feitas a partir das mesmas - Google Patents
soluções de retinóide e formulações feitas a partir das mesmasInfo
- Publication number
- BRPI0517684A BRPI0517684A BRPI0517684-0A BRPI0517684A BRPI0517684A BR PI0517684 A BRPI0517684 A BR PI0517684A BR PI0517684 A BRPI0517684 A BR PI0517684A BR PI0517684 A BRPI0517684 A BR PI0517684A
- Authority
- BR
- Brazil
- Prior art keywords
- retinoid
- same
- formulations made
- completely
- solubilized
- Prior art date
Links
- 150000004492 retinoid derivatives Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 abstract 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 239000004342 Benzoyl peroxide Substances 0.000 abstract 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 235000019400 benzoyl peroxide Nutrition 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- KDLRVYVGXIQJDK-AWPVFWJPSA-N clindamycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@H](C)Cl)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 KDLRVYVGXIQJDK-AWPVFWJPSA-N 0.000 abstract 1
- 229960002227 clindamycin Drugs 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 229940031578 diisopropyl adipate Drugs 0.000 abstract 1
- DLAHAXOYRFRPFQ-UHFFFAOYSA-N dodecyl benzoate Chemical compound CCCCCCCCCCCCOC(=O)C1=CC=CC=C1 DLAHAXOYRFRPFQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
SOLUçõES DE RETINóIDE E FORMULAçõES FEITAS A PARTIR DAS MESMAS. Composições para aplicação tópica para tratamento de um distúrbio da pele (por exemplo, acne) incluindo um retinóide, o qual é solubilizado totalmente em álcool, somente com o auxílio de co-solventes como ésteres (por exemplo, benzoato de alquila, palmitato de isopropila, miristato de isopropila, adipato de diisopropila e seus derivados). Esse retinóide totalmente solubilizado pode ser utilizado para formular um sistema de emulsão ou suspensão de líquido a pó contendo um segundo ativo, como um antibiótico (por exemplo, clindamicina) ou peróxido de benzoila.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/984,630 US7662855B2 (en) | 2004-05-11 | 2004-11-09 | Retinoid solutions and formulations made therefrom |
| US13287705A | 2005-05-19 | 2005-05-19 | |
| PCT/US2005/040510 WO2006053006A2 (en) | 2004-11-09 | 2005-11-09 | Retinoid solutions and formulations made therefrom |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0517684A true BRPI0517684A (pt) | 2008-10-14 |
Family
ID=36190667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0517684-0A BRPI0517684A (pt) | 2004-11-09 | 2005-11-09 | soluções de retinóide e formulações feitas a partir das mesmas |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1809244B1 (pt) |
| JP (1) | JP2008519764A (pt) |
| AT (1) | ATE467411T1 (pt) |
| BR (1) | BRPI0517684A (pt) |
| CA (1) | CA2586798A1 (pt) |
| DE (1) | DE602005021238D1 (pt) |
| ES (1) | ES2344214T3 (pt) |
| MX (1) | MX2007005449A (pt) |
| WO (1) | WO2006053006A2 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018154145A2 (en) * | 2018-03-29 | 2018-08-30 | Symrise Ag | Compounds for skin improvement / treatment |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4275222A (en) | 1978-10-10 | 1981-06-23 | Finetex, Inc. | Benzoate ester compositions |
| US4293544A (en) | 1979-03-07 | 1981-10-06 | Finetex Incorporated | Fluid and semi-fluid compositions including benzoate esters |
| US4278655A (en) | 1979-03-07 | 1981-07-14 | Finetex, Inc. | Antiperspirant composition |
| US4322545A (en) | 1979-09-14 | 1982-03-30 | Finetex, Inc. | Benzoic acid esters |
| US5514672A (en) * | 1981-02-17 | 1996-05-07 | Bazzano; Gail S. | Use of retinoids and compositions containing same for hair growth |
| US4323694A (en) | 1981-04-13 | 1982-04-06 | Finetex, Inc. | Benzoic acid esters |
| US5721275A (en) | 1989-06-07 | 1998-02-24 | Bazzano; Gail S. | Slow release vehicles for minimizing skin irritancy of topical compositions |
| US5260292A (en) * | 1991-03-05 | 1993-11-09 | Marvin S. Towsend | Topical treatment of acne with aminopenicillins |
| RU2134101C1 (ru) * | 1993-07-01 | 1999-08-10 | Яманаухи Эуропе Б.В. | Стабильные местнодействующие ретиноидные композиции |
| FR2710841B1 (fr) * | 1993-10-05 | 1995-11-17 | Oreal | Composition cosmétique ou pharmaceutique pour la peau, anhydre et stable, à base de rétinol et son utilisation en vue du traitement des maladies de la peau. |
| US5632996A (en) | 1995-04-14 | 1997-05-27 | Imaginative Research Associates, Inc. | Benzoyl peroxide and benzoate ester containing compositions suitable for contact with skin |
| US6284234B1 (en) * | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| DE60119693T2 (de) * | 2000-01-31 | 2007-04-26 | Engelhard Corp. | Tensidfreie topische zusammensetzungen und verfahren zur schnellen herstellung davon |
| US6387383B1 (en) * | 2000-08-03 | 2002-05-14 | Dow Pharmaceutical Sciences | Topical low-viscosity gel composition |
| US7060732B2 (en) * | 2000-12-12 | 2006-06-13 | Imaginative Research Associates, Inc. | Antibiotic/benzoyl peroxide dispenser |
| FR2833841B1 (fr) * | 2001-12-21 | 2005-07-22 | Galderma Res & Dev | Gel comprenant au moins un retinoide et du peroxyde de benzoyle |
| JP4400705B2 (ja) * | 2002-03-29 | 2010-01-20 | 株式会社タニ | 内容物の混合構造を有する包装容器 |
| US20030215493A1 (en) * | 2002-04-30 | 2003-11-20 | Patel Pravin M. | Composition and method for dermatological treatment |
| GB0301577D0 (en) * | 2003-01-23 | 2003-02-26 | Edko Pazarlama Tanitim Ltd Sti | Topical pharmaceutical and/or cosmetic dispense systems |
| US7662855B2 (en) * | 2004-05-11 | 2010-02-16 | Imaginative Research Associates, Inc. | Retinoid solutions and formulations made therefrom |
-
2005
- 2005-11-09 EP EP05826137A patent/EP1809244B1/en not_active Expired - Lifetime
- 2005-11-09 DE DE602005021238T patent/DE602005021238D1/de not_active Expired - Lifetime
- 2005-11-09 CA CA002586798A patent/CA2586798A1/en not_active Abandoned
- 2005-11-09 BR BRPI0517684-0A patent/BRPI0517684A/pt not_active IP Right Cessation
- 2005-11-09 JP JP2007540187A patent/JP2008519764A/ja active Pending
- 2005-11-09 ES ES05826137T patent/ES2344214T3/es not_active Expired - Lifetime
- 2005-11-09 MX MX2007005449A patent/MX2007005449A/es unknown
- 2005-11-09 AT AT05826137T patent/ATE467411T1/de not_active IP Right Cessation
- 2005-11-09 WO PCT/US2005/040510 patent/WO2006053006A2/en not_active Ceased
- 2005-11-09 EP EP09005071A patent/EP2145618A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1809244B1 (en) | 2010-05-12 |
| EP2145618A1 (en) | 2010-01-20 |
| ATE467411T1 (de) | 2010-05-15 |
| WO2006053006A9 (en) | 2006-07-27 |
| WO2006053006A2 (en) | 2006-05-18 |
| JP2008519764A (ja) | 2008-06-12 |
| CA2586798A1 (en) | 2006-05-18 |
| MX2007005449A (es) | 2007-12-07 |
| WO2006053006A3 (en) | 2006-09-08 |
| ES2344214T3 (es) | 2010-08-20 |
| DE602005021238D1 (de) | 2010-06-24 |
| EP1809244A2 (en) | 2007-07-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |