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BRPI0516176A - polipeptìdeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou l-citrulina - Google Patents

polipeptìdeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou l-citrulina

Info

Publication number
BRPI0516176A
BRPI0516176A BRPI0516176-2A BRPI0516176A BRPI0516176A BR PI0516176 A BRPI0516176 A BR PI0516176A BR PI0516176 A BRPI0516176 A BR PI0516176A BR PI0516176 A BRPI0516176 A BR PI0516176A
Authority
BR
Brazil
Prior art keywords
amino acid
polypeptide
citrulline
ornithine
arginine
Prior art date
Application number
BRPI0516176-2A
Other languages
English (en)
Inventor
Masato Ikeda
Tetsuo Nakano
Satochi Mitsuhashi
Mikiro Hayashi
Kenji Tanaka
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of BRPI0516176A publication Critical patent/BRPI0516176A/pt
Publication of BRPI0516176B1 publication Critical patent/BRPI0516176B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02008—Acetylglutamate kinase (2.7.2.8)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

POLIPEPTìDEO, DNA, MICROORGANISMO, E, PROCESSO PARA PRODUZIR L-ARGININA, L-ORNITINA OU L-CITRULINA. Pretende-se fornecer um polipeptídeo tendo (i) uma seqüência de aminoácidos derivada da seqüência de aminoácidos representada por SEQ ID NO: 1 por substituição de um ou mais aminoácidos nas seqüências de aminoácidos das posições 20 e 38 a partir do término N, ou (ii) uma seqüência de aminoácidos derivada da seqüência de aminoácidos representada por SEQ ID NO: 1 por substituição de um ou mais aminoácidos nas seqüências de aminoácidos das posições 20 e 38 a partir do término N e deleção, substituição ou adição de um ou mais aminoácidos na seqüência de aminoácidos das posições 1 a 19 ou das posições 39 a 294, e tendo uma atividade de N-acetilglutamato quinase.
BRPI0516176-2A 2004-09-28 2005-09-28 Polipeptídeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou lcitrulina BRPI0516176B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004280855 2004-09-28
JP2004-280855 2004-09-28
PCT/JP2005/017877 WO2006035831A1 (ja) 2004-09-28 2005-09-28 Ｌ－アルギニン、ｌ－オルニチンまたはｌ－シトルリンの製造法

Publications (2)

Publication Number Publication Date
BRPI0516176A true BRPI0516176A (pt) 2008-08-26
BRPI0516176B1 BRPI0516176B1 (pt) 2020-12-29

Family

ID=36118977

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516176-2A BRPI0516176B1 (pt) 2004-09-28 2005-09-28 Polipeptídeo, dna, microorganismo, e, processo para produzir l-arginina, l-ornitina ou lcitrulina

Country Status (9)

Country Link
US (1) US7741081B2 (pt)
EP (1) EP1801206B1 (pt)
JP (1) JP4881739B2 (pt)
CN (1) CN101027389B (pt)
AT (1) ATE462000T1 (pt)
BR (1) BRPI0516176B1 (pt)
DE (1) DE602005020165D1 (pt)
ES (1) ES2340405T3 (pt)
WO (1) WO2006035831A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
US8692070B2 (en) * 2009-11-04 2014-04-08 Iowa Corn Promotion Board Plants with improved nitrogen utilization and stress tolerance
JP5875869B2 (ja) * 2009-12-17 2016-03-02 Ｍｃフードスペシャリティーズ株式会社 アルギニン高含有酵母エキスおよびその製造方法
DE102010003419B4 (de) * 2010-03-30 2019-09-12 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von L-Ornithin
CN101863801A (zh) * 2010-06-12 2010-10-20 徐州医学院 一种光学活性瓜氨酸或高瓜氨酸的制备方法
KR101372635B1 (ko) * 2010-12-08 2014-03-13 씨제이제일제당 (주) 오르니틴 생산능이 향상된 미생물 및 이를 이용하여 오르니틴을 생산하는 방법
WO2012108493A1 (ja) 2011-02-09 2012-08-16 協和発酵バイオ株式会社 発酵法による目的物質の製造法
RU2496867C2 (ru) 2011-04-25 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии
BR112013016373B1 (pt) 2011-11-11 2021-05-18 Ajinomoto Co., Inc método para produzir uma substância alvo
US20150118720A1 (en) * 2012-04-13 2015-04-30 Kyowa Hakko Bio Co., Ltd. Process for producing amino acid
PE20150681A1 (es) 2013-05-13 2015-05-15 Ajinomoto Kk Metodo para producir l-aminoacidos
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
ES2694011T3 (es) 2013-10-21 2018-12-17 Ajinomoto Co., Inc. Método para producir L-aminoácido
BR112016008830B1 (pt) 2013-10-23 2023-02-23 Ajinomoto Co., Inc Método para produzir uma substância alvo
CN104031933A (zh) * 2014-05-08 2014-09-10 江南大学 一株l-鸟氨酸合成菌的构建及其应用方法
KR101835935B1 (ko) 2014-10-13 2018-03-12 씨제이제일제당 (주) L-아르기닌을 생산하는 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌의 제조 방법
US9487764B2 (en) * 2014-12-05 2016-11-08 Synlogic, Inc. Bacteria engineered to treat diseases associated with hyperammonemia
CN105017086B (zh) * 2015-07-01 2017-05-03 滨州市生物技术研究院有限责任公司 一种l‑瓜氨酸分离纯化的方法
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系ｌ−アミノ酸の製造法
CN110195088B (zh) * 2018-02-26 2022-09-27 中国科学院分子植物科学卓越创新中心 一种精氨酸水解酶及其编码基因和应用
CN111394295B (zh) * 2019-11-06 2023-03-10 上海健康医学院 一种制备固定化精氨酸脱亚胺酶及生产[14/15n]-l-瓜氨酸的方法
KR102433234B1 (ko) * 2020-09-29 2022-08-18 대상 주식회사 L-시트룰린 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-시트룰린의 생산 방법
KR20240013961A (ko) * 2022-07-21 2024-01-31 대상 주식회사 L-아르기닌 또는 l-시트룰린 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-아르기닌 또는 l-시트룰린의 생산 방법
WO2025159353A1 (ko) * 2024-01-25 2025-07-31 대상 주식회사 L-시트룰린 또는 l-아르기닌 생산능이 향상된 변이 미생물 및 이를 이용한 l-시트룰린 또는 l-아르기닌의 생산 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0755155B2 (ja) 1986-09-10 1995-06-14 協和醗酵工業株式会社 アミノ酸の製造法
JPH0728749B2 (ja) 1986-09-22 1995-04-05 協和醗酵工業株式会社 Ｌ−アルギニンの製造法
WO2001002583A2 (en) * 1999-07-01 2001-01-11 Basf Aktiengesellschaft Orynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
US7160705B2 (en) * 2000-04-28 2007-01-09 Ajinomoto Co., Inc. Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine
JP2002051790A (ja) * 2000-04-28 2002-02-19 Ajinomoto Co Inc コリネ型細菌のアルギニンリプレッサー欠失株及びｌ−アルギニンの製造法
EP1360298A2 (en) * 2001-02-16 2003-11-12 Degussa AG Nucleotide sequences of the ribosomal protein s12 gene (rpsl) from corynebacterium glutamicum
DE10154292A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Stoffwechselweg-Proteine codieren

Also Published As

Publication number Publication date
CN101027389A (zh) 2007-08-29
US7741081B2 (en) 2010-06-22
EP1801206B1 (en) 2010-03-24
EP1801206A4 (en) 2009-01-14
BRPI0516176B1 (pt) 2020-12-29
EP1801206A1 (en) 2007-06-27
ATE462000T1 (de) 2010-04-15
DE602005020165D1 (de) 2010-05-06
JPWO2006035831A1 (ja) 2008-05-15
ES2340405T3 (es) 2010-06-02
JP4881739B2 (ja) 2012-02-22
WO2006035831A1 (ja) 2006-04-06
US20090123980A1 (en) 2009-05-14
CN101027389B (zh) 2012-09-26

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: KYOWA HAKKO KIRIN CO., LTD. (JP)

Free format text: ALTERADO DE: KYOWA HAKKO KOGYO CO., LTD.

B25A Requested transfer of rights approved

Owner name: KYOWA HAKKO BIO CO., LTD. (JP)

Free format text: TRANSFERIDO DE: KYOWA HAKKO KIRIN CO., LTD.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.2 NA RPI NO 2540 DE 10/09/2019 POR TER SIDO INDEVIDA.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/12/2020, OBSERVADAS AS CONDICOES LEGAIS.

B25A Requested transfer of rights approved

Owner name: PLUMINO PRECISION FERMENTATION JAPAN CO., LTD. (JP)