BRPI0416201A - métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis - Google Patents
métodos para purificação de toxina coqueluche e peptìdios neles utilizáveisInfo
- Publication number
- BRPI0416201A BRPI0416201A BRPI0416201-3A BRPI0416201A BRPI0416201A BR PI0416201 A BRPI0416201 A BR PI0416201A BR PI0416201 A BRPI0416201 A BR PI0416201A BR PI0416201 A BRPI0416201 A BR PI0416201A
- Authority
- BR
- Brazil
- Prior art keywords
- purification
- methods
- pertussis toxin
- peptides
- usable
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000000746 purification Methods 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 108010081690 Pertussis Toxin Proteins 0.000 title 1
- 201000005702 Pertussis Diseases 0.000 abstract 2
- 239000003053 toxin Substances 0.000 abstract 2
- 231100000765 toxin Toxicity 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- C07K14/003—Peptide-nucleic acids (PNAs)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MéTODOS PARA PURIFICAçãO DE TOXINA COQUELUCHE E PEPTìDIOS NELES UTILIZáVEIS". A presente invenção se refere a reagentes e métodos para a purificação de toxina Pertussis (PT).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52388103P | 2003-11-20 | 2003-11-20 | |
| PCT/US2004/038700 WO2005051985A2 (en) | 2003-11-20 | 2004-11-18 | Methods for purifying pertussis toxin and peptides useful therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0416201A true BRPI0416201A (pt) | 2006-12-26 |
Family
ID=34632841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0416201-3A BRPI0416201A (pt) | 2003-11-20 | 2004-11-18 | métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8299210B2 (pt) |
| EP (1) | EP1692313A2 (pt) |
| JP (2) | JP4885729B2 (pt) |
| KR (2) | KR101320905B1 (pt) |
| CN (1) | CN1906307B (pt) |
| AU (1) | AU2004292547B9 (pt) |
| BR (1) | BRPI0416201A (pt) |
| CA (1) | CA2546343A1 (pt) |
| IL (3) | IL175630A (pt) |
| WO (1) | WO2005051985A2 (pt) |
| ZA (1) | ZA200604081B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1692313A2 (en) * | 2003-11-20 | 2006-08-23 | Sanofi Pasteur Inc. | Methods for purifying pertussis toxin and peptides useful therefor |
| US7749957B2 (en) | 2006-04-06 | 2010-07-06 | E.I. Du Pont De Nemours And Company | Clay-binding peptides and methods of use |
| SI2379096T1 (sl) | 2008-12-19 | 2020-03-31 | Baxalta GmbH | Zaviralci TFPI in postopki uporabe |
| WO2010131111A1 (en) * | 2009-05-11 | 2010-11-18 | Novartis Ag | Antigen purification process for pertactin antigen |
| CA2793465C (en) * | 2010-03-19 | 2022-06-14 | Baxter International Inc. | Tfpi inhibitors and methods of use |
| NZ724133A (en) | 2012-03-21 | 2020-07-31 | Baxalta Inc | Tfpi inhibitors and methods of use |
| CN105974122B (zh) * | 2016-05-04 | 2018-09-28 | 华东医药(杭州)基因科技有限公司 | 一种检测外泌体gpc1蛋白的方法 |
| CN113933438B (zh) * | 2021-11-11 | 2023-11-10 | 威海华洋药业有限公司 | 一种紫芪克咳口服液的含量测定方法及制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970162A (en) * | 1985-11-13 | 1990-11-13 | The United States Of America As Represented By The Department Of Health And Human Services | Human-mouse hybrid cell line expressing monocyte-macrophage properties |
| US5332583A (en) * | 1987-11-24 | 1994-07-26 | Connaught Laboratories Limited | Vaccine containing genetically-detoxified pertussis holotoxin |
| US5358868A (en) * | 1987-11-24 | 1994-10-25 | Connaught Laboratories Limited | Genetic detoxification of pertussis toxin |
| GB8727489D0 (en) * | 1987-11-24 | 1987-12-23 | Connaught Lab | Detoxification of pertussis toxin |
| US5244657A (en) * | 1987-11-24 | 1993-09-14 | Connaught Laboratories Limited | Genetic detoxification of pertussis toxin |
| US5221618A (en) * | 1987-11-24 | 1993-06-22 | Connaught Laboratories Limited | Genetic detoxification of pertussis toxin |
| GB8807860D0 (en) * | 1988-04-05 | 1988-05-05 | Connaught Lab | Pertussis vaccine |
| US5856122A (en) * | 1993-08-24 | 1999-01-05 | University Of Alberta | Modification of pertussis toxin |
| US6696065B1 (en) * | 1995-05-04 | 2004-02-24 | Aventis Pastuer Limited | Acellular pertussis vaccines and methods of preparation thereof |
| NZ306391A (en) * | 1995-05-04 | 1999-03-29 | Connaught Lab | Acellular pertussis vaccines comprising purified toxin, filamentous haemagglutinin, pertactin and fimbrial agglutinogins |
| US5877298A (en) * | 1995-05-04 | 1999-03-02 | Connaught Lab | Acellular pertussis vaccines and methods of preparing thereof |
| AU757955B2 (en) * | 1998-08-17 | 2003-03-13 | Bristol-Myers Squibb Company | Identification of compound-protein interactions using libraries of protein-nucleic acid fusion molecules |
| ES2280131T3 (es) * | 1998-12-02 | 2007-09-01 | Adnexus Therapeutics, Inc. | Fusiones de adn-proteina y utilizaciones de las mismas. |
| JP2003500081A (ja) * | 1999-06-01 | 2003-01-07 | フィロス インク. | 5’核酸−タンパク質結合体の生成法 |
| HK1045334A1 (zh) * | 1999-07-27 | 2002-11-22 | Phylos, Inc. | 缩氨酸受体结紮方法 |
| CA2382545C (en) * | 1999-08-27 | 2013-08-13 | Phylos, Inc. | Methods for encoding and sorting in vitro translated proteins |
| US7115284B2 (en) * | 2003-08-11 | 2006-10-03 | Ayurvedic-Life International, Llc | Compositions for diabetes treatment and prophylaxis |
| EP1692313A2 (en) * | 2003-11-20 | 2006-08-23 | Sanofi Pasteur Inc. | Methods for purifying pertussis toxin and peptides useful therefor |
| WO2007038619A2 (en) * | 2005-09-27 | 2007-04-05 | Amunix, Inc. | Proteinaceous pharmaceuticals and uses thereof |
| US20080241281A1 (en) * | 2007-03-29 | 2008-10-02 | Texas Tech University System | Compositions & methods for activation and inhibition of Staphylococcus aureus biofilm development |
-
2004
- 2004-11-18 EP EP04811416A patent/EP1692313A2/en not_active Withdrawn
- 2004-11-18 US US10/579,655 patent/US8299210B2/en not_active Expired - Fee Related
- 2004-11-18 AU AU2004292547A patent/AU2004292547B9/en not_active Ceased
- 2004-11-18 CA CA002546343A patent/CA2546343A1/en not_active Abandoned
- 2004-11-18 KR KR1020067009867A patent/KR101320905B1/ko not_active Expired - Fee Related
- 2004-11-18 JP JP2006541372A patent/JP4885729B2/ja not_active Expired - Fee Related
- 2004-11-18 KR KR1020127025340A patent/KR101337320B1/ko not_active Expired - Fee Related
- 2004-11-18 WO PCT/US2004/038700 patent/WO2005051985A2/en not_active Ceased
- 2004-11-18 CN CN2004800405572A patent/CN1906307B/zh not_active Expired - Fee Related
- 2004-11-18 BR BRPI0416201-3A patent/BRPI0416201A/pt not_active Application Discontinuation
-
2006
- 2006-05-14 IL IL175630A patent/IL175630A/en not_active IP Right Cessation
- 2006-05-19 ZA ZA200604081A patent/ZA200604081B/en unknown
-
2010
- 2010-04-22 IL IL205274A patent/IL205274A/en active IP Right Grant
- 2010-04-22 IL IL205275A patent/IL205275A/en active IP Right Grant
-
2011
- 2011-05-16 JP JP2011109629A patent/JP5379187B2/ja not_active Expired - Fee Related
-
2012
- 2012-07-30 US US13/561,471 patent/US9145445B2/en not_active Expired - Fee Related
-
2015
- 2015-04-06 US US14/679,503 patent/US20160032258A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2546343A1 (en) | 2005-06-09 |
| AU2004292547B9 (en) | 2012-04-26 |
| KR101337320B1 (ko) | 2013-12-06 |
| KR20060129195A (ko) | 2006-12-15 |
| IL205274A0 (en) | 2011-07-31 |
| IL205275A0 (en) | 2011-07-31 |
| CN1906307A (zh) | 2007-01-31 |
| AU2004292547B2 (en) | 2011-12-22 |
| IL175630A (en) | 2015-10-29 |
| WO2005051985A3 (en) | 2005-09-29 |
| US20160032258A1 (en) | 2016-02-04 |
| US20090215113A1 (en) | 2009-08-27 |
| WO2005051985A2 (en) | 2005-06-09 |
| EP1692313A2 (en) | 2006-08-23 |
| US8299210B2 (en) | 2012-10-30 |
| IL175630A0 (en) | 2006-09-05 |
| HK1099655A1 (en) | 2007-08-17 |
| KR101320905B1 (ko) | 2013-11-06 |
| JP2011173919A (ja) | 2011-09-08 |
| IL205275A (en) | 2013-07-31 |
| US9145445B2 (en) | 2015-09-29 |
| KR20120117942A (ko) | 2012-10-24 |
| JP5379187B2 (ja) | 2013-12-25 |
| ZA200604081B (en) | 2007-09-26 |
| JP4885729B2 (ja) | 2012-02-29 |
| JP2008504802A (ja) | 2008-02-21 |
| AU2004292547A1 (en) | 2005-06-09 |
| US20140187742A1 (en) | 2014-07-03 |
| IL205274A (en) | 2013-07-31 |
| CN1906307B (zh) | 2011-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |