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BRPI0416132A - sistema e método para liberação de vacina transdérmica - Google Patents

sistema e método para liberação de vacina transdérmica

Info

Publication number
BRPI0416132A
BRPI0416132A BRPI0416132-7A BRPI0416132A BRPI0416132A BR PI0416132 A BRPI0416132 A BR PI0416132A BR PI0416132 A BRPI0416132 A BR PI0416132A BR PI0416132 A BRPI0416132 A BR PI0416132A
Authority
BR
Brazil
Prior art keywords
microprojections
vaccine
transdermal
iontophoresis
electrode
Prior art date
Application number
BRPI0416132-7A
Other languages
English (en)
Inventor
Janardhanan Subramony
Joseph B Phipps
Michel J N Cormier
Georg Widera
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0416132A publication Critical patent/BRPI0416132A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

"SISTEMA E MéTODO PARA LIBERAçãO, DE VACINA TRANSDéRMICA". Um sistema e método para liberar transdermicamente uma vacina para um paciente, incluindo um dispositivo de liberação de iontoforese que tem um eletrodo doador, um contra-eletrodo, e circuito elétrico para suprir energia de iontoforese para os eletrodos, e um membro de microprojeção não eletroativo que possui uma pluralidade de microprojeções que penetram o estrato córneo estendendo-se a partir dele. A vacina pode estar contida em uma formulação de hidrogel em um reservatório de agente disposto próximo ao eletrodo doador, em um revestimento biocompatível que é disposto sobre as microprojeções ou em ambos.
BRPI0416132-7A 2003-10-31 2004-10-21 sistema e método para liberação de vacina transdérmica BRPI0416132A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51618403P 2003-10-31 2003-10-31
PCT/US2004/034924 WO2005044366A2 (en) 2003-10-31 2004-10-21 System and method for transdermal vaccine delivery

Publications (1)

Publication Number Publication Date
BRPI0416132A true BRPI0416132A (pt) 2007-01-02

Family

ID=34572873

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416132-7A BRPI0416132A (pt) 2003-10-31 2004-10-21 sistema e método para liberação de vacina transdérmica

Country Status (11)

Country Link
US (1) US20050123565A1 (pt)
EP (1) EP1680178A4 (pt)
JP (1) JP2007509704A (pt)
KR (1) KR20060127394A (pt)
CN (1) CN1897920A (pt)
AR (1) AR046922A1 (pt)
AU (1) AU2004287411A1 (pt)
BR (1) BRPI0416132A (pt)
CA (1) CA2543639A1 (pt)
TW (1) TW200528153A (pt)
WO (1) WO2005044366A2 (pt)

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IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
EP1768742A4 (en) * 2004-07-06 2007-10-17 Transpharma Medical Ltd ADMINISTRATION SYSTEM FOR TRANSDERMAL IMMUNIZATION
US8048017B2 (en) 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
AU2006252377A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2006131931A2 (en) * 2005-06-10 2006-12-14 Transpharma Medical, Ltd. Patch for transdermal drug delivery
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
WO2007033015A1 (en) * 2005-09-12 2007-03-22 Alza Corporation Coatable transdermal delivery microprojection assembly
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070083185A1 (en) * 2005-09-30 2007-04-12 Darrick Carter Iontophoretic device and method of delivery of active agents to biological interface
WO2007061781A1 (en) * 2005-11-18 2007-05-31 3M Innovative Properties Company Coatable compositions, coatings derived therefrom and microarrays having such coatings
US7848801B2 (en) * 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US20080287857A1 (en) * 2006-02-11 2008-11-20 Rune Kjeken Device and method for single-needle in vivo electroporation
US10369359B2 (en) * 2006-02-11 2019-08-06 Genetronics, Inc. Device and method for single-needle in vivo electroporation
EP2005990B1 (en) * 2006-04-07 2013-08-28 Hisamitsu Pharmaceutical Co., Inc. Microneedle device and transdermal administration device provided with microneedles
US7687103B2 (en) * 2006-08-31 2010-03-30 Gamida For Life B.V. Compositions and methods for preserving permeation layers for use on active electronic matrix devices
US20080214987A1 (en) 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
JP5298011B2 (ja) * 2007-05-15 2013-09-25 久光製薬株式会社 マイクロニードルのコーティング方法
AU2008302158A1 (en) * 2007-09-20 2009-03-26 Transport Pharmaceuticals, Inc. Method of enhancing iontophoretic delivery of a peptide
WO2009047365A1 (en) * 2007-10-12 2009-04-16 Capsulution Nanoscience Ag Drug delivery system
EP2211918B1 (en) * 2007-10-29 2017-10-18 Syneron Medical Ltd. Vertical patch drying
JPWO2010001671A1 (ja) 2008-06-30 2011-12-15 久光製薬株式会社 マイクロニードルデバイスおよびマイクロニードルデバイスによるインフルエンザワクチンの奏功性を上昇させる方法
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US8781576B2 (en) 2009-03-17 2014-07-15 Cardiothrive, Inc. Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current
EP2408521B1 (en) * 2009-03-17 2014-06-25 Cardio Thrive, Inc External defibrillator
CN102458359B (zh) 2009-06-10 2015-01-28 久光制药株式会社 微针装置
KR101686692B1 (ko) 2009-07-23 2016-12-14 히사미쓰 세이야꾸 가부시키가이샤 마이크로니들 어레이
US20120222979A1 (en) 2011-03-04 2012-09-06 Elwha LLC, a limited liability company of the State of Delaware Glassy compositions
CN103796683A (zh) 2011-04-21 2014-05-14 塔夫茨大学信托人 用于活性试剂稳定化的方法和组合物
KR102171142B1 (ko) * 2011-06-28 2020-10-28 이노비오 파마수티컬즈, 인크. 최소 침습 피부 전기천공 장치
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US10279189B2 (en) 2013-06-14 2019-05-07 Cardiothrive, Inc. Wearable multiphasic cardioverter defibrillator system and method
US10149973B2 (en) 2013-06-14 2018-12-11 Cardiothrive, Inc. Multipart non-uniform patient contact interface and method of use
US9907970B2 (en) 2013-06-14 2018-03-06 Cardiothrive, Inc. Therapeutic system and method using biphasic or multiphasic pulse waveform
US9833630B2 (en) 2013-06-14 2017-12-05 Cardiothrive, Inc. Biphasic or multiphasic pulse waveform and method
US9616243B2 (en) 2013-06-14 2017-04-11 Cardiothrive, Inc. Dynamically adjustable multiphasic defibrillator pulse system and method
FR3024368A1 (fr) 2014-07-29 2016-02-05 Oreal Dispositif d'iontophorese a embout multi-electrodes
KR102552848B1 (ko) * 2016-08-29 2023-07-06 더 리전츠 오브 더 유니버시티 오브 캘리포니아 피부 치료를 위한 이온성 약제에 기초한 국소 제형
RU2762607C2 (ru) 2016-09-13 2021-12-21 Аллерган, Инк. Стабилизированные небелковые композиции клостридиального токсина
AU2017327009A1 (en) 2016-09-19 2019-04-04 Vaxess Technologies, Inc. Vaccine formulations with increased stability
WO2019066113A1 (ko) * 2017-09-29 2019-04-04 한국기계연구원 플렉서블 활성종 발생기 및 이의 용도
US10828500B2 (en) 2017-12-22 2020-11-10 Cardiothrive, Inc. External defibrillator
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WO2003002069A2 (en) * 2001-06-29 2003-01-09 Becton, Dickinson And Company Intradermal delivery of vaccines and gene therapeutic agents via microcannula

Also Published As

Publication number Publication date
KR20060127394A (ko) 2006-12-12
AR046922A1 (es) 2006-01-04
TW200528153A (en) 2005-09-01
EP1680178A4 (en) 2008-01-02
WO2005044366A3 (en) 2006-03-16
CN1897920A (zh) 2007-01-17
US20050123565A1 (en) 2005-06-09
WO2005044366A2 (en) 2005-05-19
CA2543639A1 (en) 2005-05-19
EP1680178A2 (en) 2006-07-19
JP2007509704A (ja) 2007-04-19
AU2004287411A1 (en) 2005-05-19

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADE(S)

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.