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BRPI0409217A - derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona - Google Patents

derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Info

Publication number
BRPI0409217A
BRPI0409217A BRPI0409217-1A BRPI0409217A BRPI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A
Authority
BR
Brazil
Prior art keywords
derivatives
bicycloexylphenyloxazolidinone
analogues
methods
antimicrobial derivatives
Prior art date
Application number
BRPI0409217-1A
Other languages
English (en)
Inventor
Adam Robert Renslo
Mikhail Fedor Gordeev
Dinesh Vinoobhai Patel
Hongwu Gao
Vara Prassad Venkata N Josyula
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0409217A publication Critical patent/BRPI0409217A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS E ANáLOGOS ANTIMICROBIANOS DA ¢3.1.0! BICICLOEXILFENILOXAZOLIDINONA". A presente invenção proporciona alguns derivados ¢3.1.0! bicíclicos de oxazolidinona de Fórmula I ou seus sais ou promedicamentos farmaceuticamente aceitáveis que são agentes antibacterianos, composições farmacêuticas que os contêm, métodos para a sua utilização e métodos para preparar estes compostos.
BRPI0409217-1A 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona BRPI0409217A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46113403P 2003-04-09 2003-04-09
PCT/IB2004/001135 WO2004089943A1 (en) 2003-04-09 2004-03-30 Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues

Publications (1)

Publication Number Publication Date
BRPI0409217A true BRPI0409217A (pt) 2006-03-28

Family

ID=33159819

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409217-1A BRPI0409217A (pt) 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Country Status (7)

Country Link
US (2) US7279494B2 (pt)
EP (1) EP1615916A1 (pt)
JP (1) JP2006522791A (pt)
BR (1) BRPI0409217A (pt)
CA (1) CA2521685A1 (pt)
MX (1) MXPA05010783A (pt)
WO (1) WO2004089943A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05013132A (es) 2003-06-03 2006-05-25 Rib X Pharmaceuticals Inc Compuestos heterociclicos de biarilo y metodos de produccion y su uso.
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
US20060247286A1 (en) * 2003-07-02 2006-11-02 Milton Hammond Oxazolidinone antibiotics and derivatives thereof
JP4607107B2 (ja) * 2003-07-02 2011-01-05 メルク・シャープ・エンド・ドーム・コーポレイション シクロプロピル基置換されたオキサゾリジノン抗生物質およびこれらの誘導体
JP2007514782A (ja) 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
JP5534497B2 (ja) 2005-06-08 2014-07-02 メリンタ セラピューティクス，インコーポレイテッド トリアゾール類の合成方法
JP5662940B2 (ja) 2008-11-20 2015-02-04 パナセア バイオテック リミテッド 新規な抗微生物薬
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物
WO2012042539A2 (en) 2010-09-28 2012-04-05 Panacea Biotec Ltd Novel bicyclic compounds
WO2012059823A1 (en) * 2010-11-03 2012-05-10 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl] - 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester
JP7743829B2 (ja) * 2021-11-05 2025-09-25 小野薬品工業株式会社 Ｋｄｍ５阻害作用を有する化合物を含有する医薬組成物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
KR20010013192A (ko) 1997-05-30 2001-02-26 로렌스 티. 마이젠헬더 티오카보닐 작용기를 갖는 옥사졸리디논 항균제
CN1288462A (zh) 1998-01-23 2001-03-21 法玛西雅厄普约翰美国公司 噁唑烷酮组合库、组合物和制备方法
WO1999064417A2 (en) 1998-06-05 1999-12-16 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
NZ519725A (en) * 1999-12-21 2004-05-28 Upjohn Co Oxazolidinones having a sulfoximine functionality and their use as antimicrobial agents
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
JP2004504321A (ja) 2000-07-17 2004-02-12 ランバクシー　ラボラトリーズ　リミテッド 抗微生物剤としてのオキサゾリジノン誘導体
DE60118241T2 (de) 2000-10-17 2006-12-28 Pharmacia & Upjohn Co. Llc, Kalamazoo Verfahren zur herstellung von oxazolidinonverbindungen
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados

Also Published As

Publication number Publication date
MXPA05010783A (es) 2005-12-12
CA2521685A1 (en) 2004-10-21
WO2004089943A8 (en) 2005-09-29
US20080090884A1 (en) 2008-04-17
WO2004089943A1 (en) 2004-10-21
JP2006522791A (ja) 2006-10-05
EP1615916A1 (en) 2006-01-18
US20050192325A1 (en) 2005-09-01
US7279494B2 (en) 2007-10-09

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.