BRPI0407727A - adjuvante de vacina de linfócito humano - Google Patents
adjuvante de vacina de linfócito humanoInfo
- Publication number
- BRPI0407727A BRPI0407727A BRPI0407727-0A BRPI0407727A BRPI0407727A BR PI0407727 A BRPI0407727 A BR PI0407727A BR PI0407727 A BRPI0407727 A BR PI0407727A BR PI0407727 A BRPI0407727 A BR PI0407727A
- Authority
- BR
- Brazil
- Prior art keywords
- adjuvant
- human lymphocyte
- vaccine adjuvant
- derived
- human
- Prior art date
Links
- 210000004698 lymphocyte Anatomy 0.000 title abstract 4
- 239000012646 vaccine adjuvant Substances 0.000 title abstract 2
- 229940124931 vaccine adjuvant Drugs 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 3
- 229960005486 vaccine Drugs 0.000 abstract 2
- 238000002619 cancer immunotherapy Methods 0.000 abstract 1
- 230000000899 immune system response Effects 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
"ADJUVANTE DE VACINA DE LINFóCITO HUMANO". A presente invenção está relacionada a um adjuvante derivado de linfócitos humanos. O adjuvante pode ser usado em combinação com vacinas tradicionais ou imunoterapia de câncer, para melhorar a resposta do sistema imune do paciente a vacina ou a outro agente imunoterapêutico. O adjuvante é derivado a partir de um sobrenadante coletado de linfócitos ativados cultivados.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44952803P | 2003-02-21 | 2003-02-21 | |
| PCT/US2004/005152 WO2005009397A2 (en) | 2003-02-21 | 2004-02-20 | Human lymphocyte vaccine adjuvant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0407727A true BRPI0407727A (pt) | 2006-05-02 |
Family
ID=34102590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0407727-0A BRPI0407727A (pt) | 2003-02-21 | 2004-02-20 | adjuvante de vacina de linfócito humano |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7745157B2 (pt) |
| EP (1) | EP1599170B1 (pt) |
| JP (1) | JP5010280B2 (pt) |
| KR (1) | KR20060023519A (pt) |
| CN (1) | CN1787835A (pt) |
| AR (1) | AR045416A1 (pt) |
| AU (1) | AU2004258799A1 (pt) |
| BR (1) | BRPI0407727A (pt) |
| CA (1) | CA2516783A1 (pt) |
| CL (1) | CL2004000340A1 (pt) |
| MX (1) | MXPA05008936A (pt) |
| RU (1) | RU2341289C2 (pt) |
| WO (1) | WO2005009397A2 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7818101B2 (en) * | 2005-12-30 | 2010-10-19 | Canadian National Railway Company | System and method for computing rail car switching solutions in a switchyard using an iterative method |
| AU2006342608A1 (en) * | 2006-04-25 | 2007-11-01 | Intercell Ag | HCV vaccinations |
| EP2091334A4 (en) * | 2006-10-31 | 2010-02-03 | Hasumi Internat Res Foundation | TUMOR TREATMENT BY INJECTION OF DENDRITIC CELLS AND CORRESPONDING VACCINE |
| US9907819B2 (en) | 2012-06-27 | 2018-03-06 | Kenichiro Hasumi | Therapy and methods of introducing immature dendritic cells and/or cytotoxic T lymphocyte and anti-TNF antibody for treatment of tumors |
| US20140205609A1 (en) * | 2013-01-24 | 2014-07-24 | Fred T. Valentine | Methods for inducing systemic immune responses to cancer |
| CN104212760B (zh) * | 2013-05-29 | 2017-08-08 | 中国科学院上海生命科学研究院 | 肌肉干细胞体外培养方法及其应用 |
| WO2015077532A1 (en) * | 2013-11-21 | 2015-05-28 | Hasumi International Research Foundation | Therapy and methods of introducing immature dendritic cells and/or cytotoxic t lymphocyte and anti-tnf antibody for treatment of tumors |
| JP6531256B2 (ja) * | 2014-11-14 | 2019-06-19 | 日本赤十字社 | 臍帯血および末梢血の凍結保存方法および凍結保存用溶液 |
| WO2020176880A1 (en) * | 2019-02-28 | 2020-09-03 | University Of Virginia Patent Foundation | Induction of highly efficacious anti-tumor and immune modulating activity: cell-free off the shelf therapeutic modality |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59116224A (ja) * | 1982-10-01 | 1984-07-05 | デイミトリ・アダモポ−ロス | 免疫反応を抑制する組成物およびその製法 |
| ATE260971T1 (de) * | 1992-04-01 | 2004-03-15 | Univ Rockefeller | Verfahren zur in vitro kultivierung dendritischer vorläuferzellen und deren verwendung zur immunogen herstellung |
| US5747024A (en) * | 1993-03-08 | 1998-05-05 | Immunex Corporation | Vaccine adjuvant comprising interleukin-15 |
| US8333996B2 (en) * | 1995-05-19 | 2012-12-18 | Etex Corporation | Calcium phosphate delivery vehicle and adjuvant |
| GB9521568D0 (en) * | 1995-10-20 | 1995-12-20 | Lynxvale Ltd | Delivery of biologically active polypeptides |
| US20020142352A1 (en) * | 1999-03-04 | 2002-10-03 | Heska Corporation | Novel ectoparasite salvia proteins and apparatus to collect such proteins |
| US6063610A (en) * | 1996-11-12 | 2000-05-16 | Heska Corporation | Carboxylesterase nucleic acid molecules, proteins and uses thereof |
| AU4102099A (en) * | 1998-05-29 | 1999-12-13 | Heska Corporation | Canine Interleukin -4 Proteins, Nucleic Acid Molecules, and Uses Thereof |
| EP1086231A2 (en) * | 1998-06-12 | 2001-03-28 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | ENHANCEMENT OF B CELL ACTIVATION AND IMMUNOGLOBULIN SECRETION BY CO-STIMULATION OF RECEPTORS FOR ANTIGEN AND EBV Gp350/220 |
| US6270758B1 (en) * | 1998-10-08 | 2001-08-07 | Duke University | Substantially non-toxic biologically active mucosal adjuvants in vertebrate subjects |
| US6573372B2 (en) * | 1999-01-07 | 2003-06-03 | Heska Corporation | Feline immunoglobulin E molecules and compositions there of |
| US6376246B1 (en) * | 1999-02-05 | 2002-04-23 | Maxygen, Inc. | Oligonucleotide mediated nucleic acid recombination |
| US6416977B1 (en) * | 1999-04-09 | 2002-07-09 | Heska Corporation | Flea chitinase nucleic acid molecules and uses thereof |
| US6406699B1 (en) * | 1999-10-05 | 2002-06-18 | Gary W. Wood | Composition and method of cancer antigen immunotherapy |
| US20020094323A1 (en) * | 2000-10-12 | 2002-07-18 | Kristoffer Hellstrand | Methods and compositions for promoting the maturation of monocytes |
| EP1434603B1 (en) * | 2001-09-28 | 2009-12-16 | Purdue Research Foundation | Method of treatment using ligand-immunogen conjugates |
| US20030124091A1 (en) | 2001-10-26 | 2003-07-03 | Large Scale Biology Corporation | Endothelial cell derived hematopoietic growth factor |
| US7736652B2 (en) * | 2002-03-21 | 2010-06-15 | The Regents Of The University Of California | Antibody fusion proteins: effective adjuvants of protein vaccination |
| AU2003224989B2 (en) * | 2002-04-19 | 2008-12-04 | Endocyte, Inc. | Adjuvant enhanced immunotherapy |
-
2004
- 2004-02-20 CA CA002516783A patent/CA2516783A1/en not_active Abandoned
- 2004-02-20 KR KR1020057015491A patent/KR20060023519A/ko not_active Withdrawn
- 2004-02-20 JP JP2006527211A patent/JP5010280B2/ja not_active Expired - Lifetime
- 2004-02-20 US US10/783,259 patent/US7745157B2/en not_active Expired - Lifetime
- 2004-02-20 RU RU2005129134/13A patent/RU2341289C2/ru active
- 2004-02-20 CN CNA200480008732XA patent/CN1787835A/zh active Pending
- 2004-02-20 MX MXPA05008936A patent/MXPA05008936A/es unknown
- 2004-02-20 BR BRPI0407727-0A patent/BRPI0407727A/pt not_active IP Right Cessation
- 2004-02-20 WO PCT/US2004/005152 patent/WO2005009397A2/en not_active Ceased
- 2004-02-20 AU AU2004258799A patent/AU2004258799A1/en not_active Abandoned
- 2004-02-20 EP EP04775788A patent/EP1599170B1/en not_active Expired - Lifetime
- 2004-02-23 AR ARP040100565A patent/AR045416A1/es unknown
- 2004-02-23 CL CL200400340A patent/CL2004000340A1/es unknown
-
2010
- 2010-06-28 US US12/824,577 patent/US8088397B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004258799A1 (en) | 2005-02-03 |
| RU2005129134A (ru) | 2006-03-27 |
| US20040241183A1 (en) | 2004-12-02 |
| EP1599170A4 (en) | 2007-05-09 |
| RU2341289C2 (ru) | 2008-12-20 |
| AR045416A1 (es) | 2005-10-26 |
| WO2005009397A2 (en) | 2005-02-03 |
| US8088397B2 (en) | 2012-01-03 |
| US7745157B2 (en) | 2010-06-29 |
| JP5010280B2 (ja) | 2012-08-29 |
| CL2004000340A1 (es) | 2005-05-20 |
| WO2005009397A3 (en) | 2005-11-17 |
| EP1599170B1 (en) | 2013-01-16 |
| EP1599170A2 (en) | 2005-11-30 |
| MXPA05008936A (es) | 2006-05-25 |
| JP2007531703A (ja) | 2007-11-08 |
| KR20060023519A (ko) | 2006-03-14 |
| CA2516783A1 (en) | 2005-02-03 |
| CN1787835A (zh) | 2006-06-14 |
| US20100266534A1 (en) | 2010-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |