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BR9915323A - Derivados pirimidina e processos para sua preparação - Google Patents

Derivados pirimidina e processos para sua preparação

Info

Publication number
BR9915323A
BR9915323A BR9915323-8A BR9915323A BR9915323A BR 9915323 A BR9915323 A BR 9915323A BR 9915323 A BR9915323 A BR 9915323A BR 9915323 A BR9915323 A BR 9915323A
Authority
BR
Brazil
Prior art keywords
processes
preparation
pyrimidine derivatives
derivatives
ingredient
Prior art date
Application number
BR9915323-8A
Other languages
English (en)
Inventor
Jong Wook Lee
Bong Yong Lee
Chang Seop Kim
Seung Kyu Lee
Song Jin Lee
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of BR9915323A publication Critical patent/BR9915323A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS PIRIMIDINA E PROCESSOS PARA SUA PREPARAçãO" A presente invenção refere-se a novos derivados pirimidina e a sais farmaceuticamente aceitáveis não-tóxicos dos mesmos, que possuem uma excelente atividade inibidora contra secreção de ácido gástrico, uma composição farmacêutica contendo os mesmos como ingrediente ativo e a um processo para preparação dos mesmos.
BR9915323-8A 1998-11-17 1999-11-09 Derivados pirimidina e processos para sua preparação BR9915323A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980049164A KR100272471B1 (ko) 1998-11-17 1998-11-17 신규의 피리미딘 유도체 및 그의 제조방법
PCT/KR1999/000669 WO2000029403A1 (en) 1998-11-17 1999-11-09 Novel pyrimidine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
BR9915323A true BR9915323A (pt) 2001-08-07

Family

ID=36201265

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915323-8A BR9915323A (pt) 1998-11-17 1999-11-09 Derivados pirimidina e processos para sua preparação

Country Status (17)

Country Link
US (1) US6545008B1 (pt)
EP (1) EP1131312B1 (pt)
JP (1) JP2002530280A (pt)
KR (1) KR100272471B1 (pt)
CN (1) CN1159312C (pt)
AT (1) ATE307809T1 (pt)
AU (1) AU762098B2 (pt)
BR (1) BR9915323A (pt)
CA (1) CA2351644A1 (pt)
DE (1) DE69927997T2 (pt)
ES (1) ES2251234T3 (pt)
HK (1) HK1041000B (pt)
HU (1) HUP0104533A3 (pt)
MX (1) MXPA01004457A (pt)
RU (1) RU2236407C2 (pt)
TR (1) TR200101388T2 (pt)
WO (1) WO2000029403A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0110338D0 (en) * 2001-04-27 2001-06-20 Sb Pharmco Inc Novel processes
JP2006528640A (ja) * 2003-07-22 2006-12-21 ニューロジェン・コーポレーション 置換ピリジン−２−イルアミン類縁体
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
NZ566862A (en) * 2005-09-27 2010-12-24 Irm Llc Diarylamine-containing compounds and compositions, and their use as modulators of C-kit receptors
CN102470126A (zh) 2009-07-09 2012-05-23 拉夸里亚创药株式会社 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂
EP2922828B1 (en) 2012-11-21 2020-07-08 PTC Therapeutics, Inc. 4,6-diamino-pyrimidine derivatives as bmi-1 inhibitors for treating cancer
TWI692477B (zh) * 2013-08-30 2020-05-01 美商Ｐｔｃ治療公司 經取代嘧啶ｂｍｉ-１抑制劑
WO2015076800A1 (en) 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors
US12023335B2 (en) 2018-08-17 2024-07-02 Ptc Therapeutics, Inc. Method for treating pancreatic cancer

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
FR2640582B1 (fr) 1988-12-21 1991-08-16 Gerard Megret Procede d'habillage d'elements de boites montees et installation pour la mise en oeuvre de ce procede
ES2081863T3 (es) 1989-03-22 1996-03-16 Ciba Geigy Ag Plaguicidas.
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
HUT64533A (en) 1990-11-06 1994-01-28 Pfizer Method for producing quinazoline derivatives for improving anti-tumoric activity and preparations containing said compounds
CA2108561A1 (en) 1991-04-17 1992-10-18 Jotham W. Coe Pyrimidine derivatives for enhancing antitumor activity
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
ATE163647T1 (de) 1993-08-26 1998-03-15 Ono Pharmaceutical Co 4-aminopyrimidin derivate
RU2153494C2 (ru) 1993-10-12 2000-07-27 Дзе Дюпон Мерк Фармасьютикал Компани 1-n-алкил-n-арилпиримидинамины, способ лечения заболеваний, фармацевтическая композиция
JP2896532B2 (ja) * 1994-08-13 1999-05-31 ユーハン コーポレーション 新規なピリミジン誘導体およびその製造方法
PT900214E (pt) * 1996-05-04 2002-03-28 Yuhan Corp Processo para a preparacao de derivados da pirimidina
BR9712392A (pt) * 1996-10-29 2000-01-25 Yuhan Corp Processos para preparar 5,6-dimetil-2-(4-fluorofenil-amino) -4- (1-metil-1,2,3,4 - tetraidroisoquinolin - 2 -il) pirimidina, 4 - halogeno - 2 - (4 - fluorofenilamino) -5,6 -dimetil-pirimidina e 1-metil-1,2,3,4-tetraidroisoquinolina, e, derivado de pirimidina
IN188411B (pt) 1997-03-27 2002-09-21 Yuhan Corp

Also Published As

Publication number Publication date
JP2002530280A (ja) 2002-09-17
TR200101388T2 (tr) 2001-10-22
CN1326453A (zh) 2001-12-12
RU2236407C2 (ru) 2004-09-20
ES2251234T3 (es) 2006-04-16
DE69927997D1 (de) 2005-12-01
US6545008B1 (en) 2003-04-08
HK1041000A1 (en) 2002-06-28
MXPA01004457A (es) 2004-04-05
CA2351644A1 (en) 2000-05-25
AU762098B2 (en) 2003-06-19
HUP0104533A3 (en) 2003-01-28
ATE307809T1 (de) 2005-11-15
EP1131312B1 (en) 2005-10-26
EP1131312A1 (en) 2001-09-12
DE69927997T2 (de) 2006-07-27
KR20000032633A (ko) 2000-06-15
HK1041000B (zh) 2004-12-31
HUP0104533A2 (hu) 2002-04-29
WO2000029403A1 (en) 2000-05-25
AU1081200A (en) 2000-06-05
KR100272471B1 (ko) 2000-11-15
CN1159312C (zh) 2004-07-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DA 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 1986 DE 27/03/2009.