[go: up one dir, main page]

BR9914399A - Composto de piridopirazina, processo para sua produção e seu uso - Google Patents

Composto de piridopirazina, processo para sua produção e seu uso

Info

Publication number
BR9914399A
BR9914399A BR9914399-2A BR9914399A BR9914399A BR 9914399 A BR9914399 A BR 9914399A BR 9914399 A BR9914399 A BR 9914399A BR 9914399 A BR9914399 A BR 9914399A
Authority
BR
Brazil
Prior art keywords
production
compound
pyridopyrazine
pyridopyrazine compound
solvate
Prior art date
Application number
BR9914399-2A
Other languages
English (en)
Inventor
Norihiko Shimazaki
Masaru Watanabe
Masaharu Ichihara
Nobutaka Kawai
Koji Machiya
Kooji Kagara
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of BR9914399A publication Critical patent/BR9914399A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"COMPOSTO DE PIRIDOPIRAZINA, PROCESSO PARA SUA PRODUçãO E SEU USO". A invenção provê sal composto de piridopirazina novo da fórmula seguinte e seu cristal, que apresentam solubilidade e estabilidade muito satisfatórias. Mais particularmente, são providos o composto da fórmula acima, seu solvato e seus cristais.
BR9914399-2A 1998-09-29 1999-09-22 Composto de piridopirazina, processo para sua produção e seu uso BR9914399A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27444098 1998-09-29
PCT/JP1999/005182 WO2000018768A1 (en) 1998-09-29 1999-09-22 Novel salts of pyridopyrazine compound and crystals thereof

Publications (1)

Publication Number Publication Date
BR9914399A true BR9914399A (pt) 2002-01-22

Family

ID=17541719

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914399-2A BR9914399A (pt) 1998-09-29 1999-09-22 Composto de piridopirazina, processo para sua produção e seu uso

Country Status (13)

Country Link
EP (1) EP1118615A4 (pt)
KR (1) KR20010075287A (pt)
CN (1) CN1328555A (pt)
AU (1) AU5758199A (pt)
BR (1) BR9914399A (pt)
CA (1) CA2345362A1 (pt)
CZ (1) CZ20011164A3 (pt)
HK (1) HK1042896A1 (pt)
HU (1) HUP0103947A3 (pt)
IL (1) IL142147A0 (pt)
TR (2) TR200200971T2 (pt)
WO (1) WO2000018768A1 (pt)
ZA (1) ZA200102566B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
DK2020243T3 (en) * 2002-05-28 2018-11-19 Astrazeneca Ab Pharmaceutical composition which can be applied topically
KR20050043923A (ko) * 2002-09-16 2005-05-11 알콘 매뉴팩츄어링, 리미티드 혈관신생 치료를 위한 ｐｄｅ-ⅳ 저해제의 용도
DE602004023921D1 (de) 2003-03-10 2009-12-17 Nycomed Gmbh Neues verfahren zur herstellung vonroflumilast
US8663694B2 (en) 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
KR20120073300A (ko) * 2009-09-30 2012-07-04 뗑따마르 에스아에스 휴대 가방 또는 조끼

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008864A1 (en) * 1978-08-15 1980-03-19 FISONS plc Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them
KR950011409B1 (ko) * 1986-09-16 1995-10-04 메르크 파텐트 게젤샤프트 미트 베슈랭크터 하프퉁 히드록시인돌 유도체
GB9413975D0 (en) * 1994-07-11 1994-08-31 Fujisawa Pharmaceutical Co New heterobicyclic derivatives

Also Published As

Publication number Publication date
IL142147A0 (en) 2002-03-10
HUP0103947A3 (en) 2002-06-28
EP1118615A1 (en) 2001-07-25
HUP0103947A2 (hu) 2002-04-29
KR20010075287A (ko) 2001-08-09
ZA200102566B (en) 2002-07-18
AU5758199A (en) 2000-04-17
CA2345362A1 (en) 2000-04-06
CZ20011164A3 (cs) 2001-12-12
TR200100893T2 (tr) 2001-11-21
WO2000018768A1 (en) 2000-04-06
CN1328555A (zh) 2001-12-26
TR200200971T2 (tr) 2002-06-21
HK1042896A1 (zh) 2002-08-30
EP1118615A4 (en) 2002-02-27

Similar Documents

Publication Publication Date Title
YU49312B (sh) Kristalni hidratni derivati 3,4,4-trisupstituisanih - peperidinil-n-alkilkarboksilata, njihovi intermedijari i postupak za dobijanje
NL1002835A1 (nl) Synergistisch stabilisatormengsel.
DK0562956T3 (da) Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
NO930517L (no) Benzimidazolylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
NO914092L (no) Nye mercaptoacetylamid-derivater som er anvendbare som inhibitorer for enkefalinase og ace
ES2072627T3 (es) Derivados de piridina y n-oxido de piridina de diarilmetilpiperidinas o piperazinas, composiciones y uso de las mismas.
BR9303993A (pt) Composto, processo para preparar o mesmo e composição farmacêutica
EA200200510A1 (ru) 4-карбоксиамино-2-этил-1,2,3,4-тетрагидрохинолин в кристаллической форме как ингибитор сетр
MX9302214A (es) Derivados de taxol y proceso para su preparacion
NO963370D0 (no) Nye mercaptoacetylamido-1,3,4,5-tetrahydro-benzo[cÅazepin-3-on-disulfidderivater som er anvendbare som inhibitorer av enkefalinase og ACE
DK0659174T3 (da) Derivater af valproinsyre og 2-valproensyreamider samt deres anvendelse som antikonvulsive midler
ES2108371T3 (es) Nuevos derivados de estradieno de 11-benzaldoxima, procedimientos para su produccion y farmacos conteniendo estos compuestos.
ES2097174T3 (es) Derivados de la 2-ciclohexan-1-il amina.
NO991494D0 (no) <beta>-sulfonylhydroksaminsyrer som matriksmetalloproteinaseinhibitorer
ES2123652T3 (es) 7-(2-aminoetil)-benzotiazolonas.
NO954768D0 (no) N-alkyltiopolyaminderivater som radiobeskyttende midler
NO922380D0 (no) Substituerte 4-fenyl-4-piperidinkarboksamider med baade lokal anestetisk og analgetisk effekt samt fremgangsmaater for deres fremstilling
FI934298A0 (fi) Kristallin tiagabine-hydrokloridmonohydrat, dess framstaellning och dess anvaendning
NO954609L (no) Niopecotiske syrederivater som antitrombiske forbindelser
BR9914399A (pt) Composto de piridopirazina, processo para sua produção e seu uso
DK0861250T3 (da) Amindin- og isothiourinstofderivater som inhibitorer for nitrogenmonoxidsyntase
BR0011339A (pt) Composto, uso, e processo para preparar o mesmo, composição farmacêutica, e, método para tratar uma condição de doença mediada por metaloproteinase
PT937043E (pt) Novos derivados tetra-hidropiridinicos substituidos processo para a sua preparacao e as composicoes farmaceuticas que os contem
ATE173471T1 (de) Pyridazinonderivate oder deren salze, verfahren zu ihrer herstellung und diese enthaltende antischockmittel
DK0745081T3 (da) Indan-2-mercaptoacetylamiddisulfidderivater, der er anvendelige som enkephalinase-inhibitorer

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.